Results 111 to 120 of about 119,198,728 (316)

RBM25 Drives Hepatocellular Carcinoma Progression by Stabilizing YAP Through Regulating Oncogenic Splicing‐switch of MYPT1

Advanced Science, EarlyView.
This study establishes that the RBM25‐PRPF40A interaction modulates MYPT1 splicing, promoting the production of the oncogenic long isoform. This isoform stabilizes YAP by suppressing its phosphorylation and subsequent proteasomal degradation, ultimately accelerating tumor growth.
Wenjing Zhang, Lili Zhi, Tian Huang, Lingya Feng, Chaoqun Chen, Huanhuan Wei, Xiaolong Liu, Lei Chen, Jinrui Zhang, Ge Zhang, Baofeng Zhao, Rong Liu, Dan Chen, Yangfan Qi, Yang Wang   +14 more
wiley   +1 more source

Shifting epidemiology and disease severity: Rethinking India’s hepatitis A strategy in the context of acute liver failure

Journal of Family Medicine and Primary Care
India is, at present, witnessing a significant epidemiological transition in hepatitis A virus (HAV) infection, shifting from high to intermediate endemicity.
Ajeet S. Bhadoria, Prajna Anirvan, Akash Roy, Rishabh Bose, Raman Kumar   +4 more
doaj   +1 more source

A Hepatocyte‐to‐Stellate Cell Axis Couples Alternate‐Day Fasting to Liver Fibrosis Resolution via ATG7 S‐Nitrosylation

Advanced Science, EarlyView.
Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Xueqiang Wang, Mengqi Zeng, Cunxiao Sun, Yuhan Gou, Zhaode Feng, Weiqiang Lv, Chaoying Yan, Hansen Wu, Pengfei Zhang, Jie Xu, Ke Cao, Hao Li, Mingge Ding, Zhongbo Liu, Xing Zhang, Jiankang Liu, Xuan Zou, Zhihui Feng   +17 more
wiley   +1 more source

Surveillance for viral hepatitis \u2014 United States, 2010

As part of CDC\u2019s National Notifiable Disease Surveillance System (NNDSS), viral hepatitis case-reports are received electronically from state health departments via CDC\u2019s National Electronic Telecommunications System for Surveillance (NETSS), a

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IJCM_300A: Clinical medicine and Public health: Is the dichotomy justified? Epidemiological investigation of a Hepatitis A case admitted at a tertiary care hospital

Indian Journal of Community Medicine
Background: Outbreaks of Hepatitis A Virus (HAV) infection have been associated with poor sanitation, inadequate sewage disposal and contamination of food and water.
Deepthi Shibu, M Mridul, S Avinash, KM Akshaya   +3 more
doaj   +1 more source

Stimulation of OGG1 Enhances Oxidative DNA Damage Repair and Protects Against Acute Liver Failure by Acetaminophen

Advanced Science, EarlyView.
Chemical switching of OGG1 by CMM‐98 accelerates oxidative DNA damage repair and enhances hepatocyte resilience during acetaminophen‐induced acute liver injury. By promoting efficient processing of OGG1‐generated repair intermediates, CMM‐98 reduces oxidative damage, preserves cellular integrity, and protects against acute liver failure, identifying ...
Zhenjun Zhao, Rahul Upadhyay, Alice Eddershaw, Chenchen Wang, Yudong Zhao, Olov Wallner, Jinhye Ryu, Nayere Taebnia, Heather Gildie, Emma Scaletti‐Hutchinson, Jonathan R. Davies, Nicole Ziegler, Andreas Krämer, Samantha C. Robinson, Marek Varga, Karolina Singerova, Zuzanna Szaruga, Elisée Wiita, İrşil Güneş, Sheila S. David, Stefan Knapp, Aimo Kannt, Miguel de Vega, Pål Stenmark, Volker M Lauschke, Maurice Michel   +25 more
wiley   +1 more source

Surveillance for viral hepatitis \u2014 United States, 2011

As part of CDC\u2019s National Notifiable Disease Surveillance System (NNDSS), viral hepatitis case-reports are received electronically from state health departments via CDC\u2019s National Electronic Telecommunications System for Surveillance (NETSS), a

core  

Surveillance for Acute Viral Hepatitis : United States, 2006 [PDF]

"Problem/Condition: In the United States, acute viral hepatitis most frequently is caused by infection with three viruses: hepatitis A virus (HAV), hepatitis B virus (HBV), and hepatitis C virus (HCV).

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Assessment the Epidemiological Status of Patients with Acute Liver Hepatitis Referred to Shahid Sadoughi Hospital of Yazd From 2015 to 2018

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2019
Introduction: Acute hepatitis has several causes. Transfusion of non-infected blood to the virus and avoidance of undesirable social contacts have reduced the prevalence of hepatitis B and C transmission.
Hassan i Salmanroghan, Mahmud Baghbanian, , Mohammad Hassan Rouzegari, Mohsen Akhondi Meybodi, MohammadKazem Amirbeigy   +4 more
doaj  

Increase in Adult Acute Hepatitis A Cases Following the Earthquake: An Epidemiological and Clinical Evaluation

Viral Hepatitis Journal
Objectives: Acute hepatitis A continues to be an important public health problem in developing countries. This study aimed to evaluate the epidemiological, clinical, and laboratory characteristics of adult cases of acute hepatitis A observed in Adana and
Özge Tüfek, Tuba Turunç, Tuğba Arslan Gülen   +2 more
doaj   +1 more source