Results 21 to 30 of about 119,198,728 (316)
Relevance. During the ongoing pandemic of a new coronavirus infection (COVID-19), assessment of humoral immunity to vaccine preventable diseases in healthcare workers is crucial to estimate the risk of healthcare-associated infections. Aim. To assess the
O. V. Samodova +2 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Hepatitis A surveillance in England--how many cases are not reported and does it really matter? [PDF]
Underreporting of hepatitis A infection in England may be high and a number of outbreaks have occurred undetected by routine surveillance. We evaluated surveillance of hepatitis A cases by employing capture-recapture analysis on data from two distinct ...
Grant, A +3 more
core +1 more source
Hepatitis A outbreak among men who have sex with men, Shinjuku, Japan, 2018
Objective: In 2018, the Shinjuku City Department of Health detected excess cases of hepatitis A virus (HAV) infection. The objectives of this investigation were to characterize the outbreak, identify transmission routes among inpatient cases and make ...
Mariya Itaki +8 more
doaj +1 more source
Sri Lanka experienced an unprecedented outbreak of hepatitis A in 2009. We extracted data from different sources to get a proper estimate of actual disease incidence during that period.
NJ Dahanayaka, T Kiyohara, SB Agampodi
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Hepatitis A is an acute liver disease caused by the hepatitis A virus (HAV), which can be prevented by means of vaccination. The standard hepatitis A vaccination schedule consists of two doses of inactivated vaccine, but for economic reasons and the ...
Mariya A. Lopatukhina +2 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Investigation of Anti-HCV, Anti-HIV, and Anti-HAV IgG Seroprevalence in HBsAg-positive Patients
Objectives: The objective of this study was to evaluate serologic markers anti-hepatitis C virus (anti-HCV), anti-hepatitis A virus immunoglobulin G (anti-HAV IgG), anti-human immunodeficiency virus antibody (anti-HIV)] associated with HCV, HAV, and HIV ...
Yeşim Çağlar, Enes Dalmanoğlu
doaj +1 more source
To the Editor: Hepatitis A virus (HAV) infection rates are very low in industrialized countries. A noticeable fall in the prevalence of HAV antibodies (anti-HAV) has been reported in southern European and Mediterranean countries such as Spain (1) and Greece (2), reflecting improvements in hygiene standards in the last decades.
D'AMELIO, Raffaele +7 more
openaire +5 more sources

