Results 31 to 40 of about 692,779 (316)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Hepatitis A is an acute liver disease caused by the hepatitis A virus (HAV), which can be prevented by means of vaccination. The standard hepatitis A vaccination schedule consists of two doses of inactivated vaccine, but for economic reasons and the ...
Mariya A. Lopatukhina +2 more
doaj +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Investigation of Anti-HCV, Anti-HIV, and Anti-HAV IgG Seroprevalence in HBsAg-positive Patients
Objectives: The objective of this study was to evaluate serologic markers anti-hepatitis C virus (anti-HCV), anti-hepatitis A virus immunoglobulin G (anti-HAV IgG), anti-human immunodeficiency virus antibody (anti-HIV)] associated with HCV, HAV, and HIV ...
Yeşim Çağlar, Enes Dalmanoğlu
doaj +1 more source
To the Editor: Hepatitis A virus (HAV) infection rates are very low in industrialized countries. A noticeable fall in the prevalence of HAV antibodies (anti-HAV) has been reported in southern European and Mediterranean countries such as Spain (1) and Greece (2), reflecting improvements in hygiene standards in the last decades.
D'AMELIO, Raffaele +7 more
openaire +5 more sources
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Evaluation of Hepatitis A Seroprevalence in Patients Admitted to a University Hospital
Objectives: Hepatitis A virus (HAV) is a ribonucleic acid virus that usually causes acute self-limiting liver disease and is transmitted via the fecal-oral route.
Yunus Emre İbik +2 more
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Introduction: Hepatitis E virus (HEV) is a non-enveloped, single-stranded positive-sense RNA virus. It is one of the most important causes of liver failures and the mortality rate arising from HEV is more common in pregnant women.
SA Sadeghi +6 more
doaj
Fikaden Berhe Hadgu, Henok Temtime Alemu Department of Pediatrics and Child Health, College of Health Sciences, Mekelle University, Tigray, EthiopiaCorrespondence: Fikaden Berhe HadguDepartment of Pediatrics and Child Health, College of Health Sciences ...
Hadgu FB, Alemu HT
doaj

