Results 31 to 40 of about 692,779 (316)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Immunological and epidemiological effectiveness of pediatric vaccination against hepatitis A using a single dose of inactivated vaccine

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии
Hepatitis A is an acute liver disease caused by the hepatitis A virus (HAV), which can be prevented by means of vaccination. The standard hepatitis A vaccination schedule consists of two doses of inactivated vaccine, but for economic reasons and the ...
Mariya A. Lopatukhina   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Investigation of Anti-HCV, Anti-HIV, and Anti-HAV IgG Seroprevalence in HBsAg-positive Patients

open access: yesViral Hepatitis Journal
Objectives: The objective of this study was to evaluate serologic markers anti-hepatitis C virus (anti-HCV), anti-hepatitis A virus immunoglobulin G (anti-HAV IgG), anti-human immunodeficiency virus antibody (anti-HIV)] associated with HCV, HAV, and HIV ...
Yeşim Çağlar, Enes Dalmanoğlu
doaj   +1 more source

Hepatitis A, Italy [PDF]

open access: yesEmerging Infectious Diseases, 2005
To the Editor: Hepatitis A virus (HAV) infection rates are very low in industrialized countries. A noticeable fall in the prevalence of HAV antibodies (anti-HAV) has been reported in southern European and Mediterranean countries such as Spain (1) and Greece (2), reflecting improvements in hygiene standards in the last decades.
D'AMELIO, Raffaele   +7 more
openaire   +5 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Evaluation of Hepatitis A Seroprevalence in Patients Admitted to a University Hospital

open access: yesViral Hepatitis Journal
Objectives: Hepatitis A virus (HAV) is a ribonucleic acid virus that usually causes acute self-limiting liver disease and is transmitted via the fecal-oral route.
Yunus Emre İbik   +2 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Cloning and expression of hepatitis E virus ORF2 as an immunogen protein in baculovirus expression system

open access: yesVaccine Research, 2018
Introduction: Hepatitis E virus (HEV) is a non-enveloped, single-stranded positive-sense RNA virus. It is one of the most important causes of liver failures and the mortality rate arising from HEV is more common in pregnant women.
SA Sadeghi   +6 more
doaj  

Pleural Effusion Associated with Anicteric Hepatitis A Virus Infection – Unusual Manifestation of a Common Disease: A Case Report

open access: yesPediatric Health, Medicine and Therapeutics, 2020
Fikaden Berhe Hadgu, Henok Temtime Alemu Department of Pediatrics and Child Health, College of Health Sciences, Mekelle University, Tigray, EthiopiaCorrespondence: Fikaden Berhe HadguDepartment of Pediatrics and Child Health, College of Health Sciences ...
Hadgu FB, Alemu HT
doaj  

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