Results 151 to 160 of about 276,512 (289)

Preventing First and Further Decompensation in Advanced Chronic Liver Disease

Liver International, Volume 46, Issue 4, April 2026.
ABSTRACT Advanced chronic liver disease (ACLD) remains a major cause of global morbidity and mortality. Preventing hepatic decompensation—both the first event and subsequent recurrences—has become a central therapeutic goal to prolong survival. The transition from the compensated phase (cACLD) to the decompensated phase (dACLD) is driven by clinically ...
Leonardo Corrêa Süffert, Bernardo de Faria Moraes, Guilherme Grossi Lopes Cançado   +2 more
wiley   +1 more source

Post-marketing safety study to evaluate pregnancy outcomes among recipients of hepatitis B vaccines. [PDF]

Hum Vaccin Immunother
Bruxvoort KJ, Sy LS, Slezak J, Ackerson BK, Qian L, Qiu S, Solano Z, Reynolds K.   +7 more
europepmc   +1 more source

Elevated Polyreactive Immunoglobulin G in Immune‐Mediated Liver Injuries With the Need for Immunosuppressive Therapy

Liver International, Volume 46, Issue 4, April 2026.
ABSTRACT Background & Aims The distinction of drug‐induced liver injury (DILI), drug‐induced autoimmune‐like hepatitis (DI‐ALH), and autoimmune hepatitis (AIH) can be challenging due to overlapping clinical characteristics. Recently, polyreactive immunoglobulin G (pIgG) was identified as a novel biomarker in AIH.
Theresa Kirchner, George N. Dalekos, Kalliopi Zachou, Mercedes Robles‐Díaz, Raúl J. Andrade, Marcial Sebode, Ansgar Lohse, Maciej K. Janik, Piotr Milkiewicz, Mirjam Kolev, Nasser Semmo, Tony Bruns, Tom Jg. Gevers, Benedetta Terziroli Beretta‐Piccoli, Heiner Wedemeyer, Elmar Jaeckel, Richard Taubert, Bastian Engel, pIgG study group   +18 more
wiley   +1 more source

Safety of Hepatitis B Vaccines (Monovalent or as Part of Combination) in Preterm Infants: A Systematic Review. [PDF]

Vaccines (Basel)
Tee QW, Odisho R, Purcell E, Purcell R, Buttery J, Nold-Petry CA, Nold MF, Nold MF, Malhotra A.   +8 more
europepmc   +1 more source

Do we need better hepatitis B vaccines? [PDF]

Indian J Med Res, 2017
Gerlich WH.
europepmc   +1 more source

Loss of confidence in vaccines following media reports of infant deaths after hepatitis B vaccination in China.

International Journal of Epidemiology, 2016
Wenzhou Yu, Da-wei Liu, Jing-shan Zheng, Yan-min Liu, Z. An, L. Rodewald, Guomin Zhang, Q. Su, Keli Li, Disha Xu, Fu-zhen Wang, Ping Yuan, Wei-dong Xia, G. Ning, Hui-hui Zheng, Yaozhu Chu, J. Cui, Mengjuan Duan, L. Hao, Yu-qing Zhou, Zhenhua Wu, Xuan Zhang, F. Cui, Li Li, Huaqing Wang   +24 more
semanticscholar   +1 more source

Care Pathways for Metabolic Dysfunction‐Associated Steatotic Liver Disease (MASLD): A State‐of‐The‐Art Review

Liver International, Volume 46, Issue 4, April 2026.
ABSTRACT Metabolic dysfunction‐Associated Steatotic Liver Disease (MASLD) is a growing clinical challenge, necessitating effective diagnostic strategies to identify advanced liver fibrosis while minimising unnecessary referrals of mild cases. Current clinical guidelines recommend care pathways utilising non‐invasive tests (NITs) to stratify patients ...
Kirsi M. A. van Eekhout, Leonard D. Broekman, Vivian D. de Jong, Maurice Michel, Rick Grobbee, Douglas Maya‐Miles, Manuel Romero‐Gómez, Jean Muris, Juan M. Mendive, Yasaman Vali, Oscar H. Franco, Jörn M. Schattenberg, Céline Fournier‐Poizat, Manuel Castro Cabezas, Maarten E. Tushuizen, Adriaan G. Holleboom   +15 more
wiley   +1 more source

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

Advanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche, Andreas Dzierza, Jan Egger, Timo Rheinberger, Christin Weilandt, Frederik R. Wurm, Ivo Nischang, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source

Case‐Based Immunology: B Cells and Systemic Sclerosis Interstitial Lung Disease

Arthritis &Rheumatology, Volume 78, Issue 3, Page 566-581, March 2026.
Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to US Food and Drug Administration–approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of ILDs of other systemic autoimmune
Nina Goldman, Voon Ong, Christopher P. Denton   +2 more
wiley   +1 more source

Neoadjuvant Therapy for Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma: Current Status, Challenges, and Future Perspectives

Cancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Gastric cancer remains a leading cause of cancer‐related mortality worldwide, with locally advanced gastric/gastroesophageal junction adenocarcinoma posing significant therapeutic challenges. Neoadjuvant therapy has emerged as a critical strategy to improve surgical outcomes and long‐term survival by reducing tumor burden and eradicating ...
Jiaqi Zhou, Chengwang Guo, Mingze Zhang, Xi Guo, Jihong Wang, Xiaojun Liu, Peng Nie, Yuntao Ma   +7 more
wiley   +1 more source