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COVID-19 vaccine immunogenicity in Mongolian adults with and without chronic hepatitis [PDF]

BMC Infectious Diseases
Background Mongolia has a high prevalence of liver disease from chronic viral hepatitis infections, which can compromise the immune response. It is unclear whether people with chronic liver disease produce a robust antibody response to the COVID-19 ...
Viviane Callier, Ganbolor Jargalsaikhan, Munguntsetseg Batkhuu, Renee Ridzon, Sally Hunsberger, Irini Sereti, Kathryn Shaw-Saliba, Shera Weyers, Alyson Francis, Naranjaral Dashdorj   +9 more
doaj   +2 more sources

Vaccination Strategies Against Hepatic Diseases: A Scoping Review [PDF]

Vaccines
Background/Objectives: Viral hepatitis remains a significant global cause of chronic liver disease, highlighting the importance of effective vaccination strategies. This review assesses recent evidence on vaccine safety and effectiveness.
Zahra Beyzaei, Bita Geramizadeh, Sara Karimzadeh, Ralf Weiskirchen   +3 more
doaj   +2 more sources

Emerging antiviral drugs and immunotherapy for chronic hepatitis B and associated liver disease [PDF]

Frontiers in Immunology
Chronic hepatitis B virus (HBV) infection is a major global cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Despite current antiviral therapies, functional cure remains elusive due to persistent HBsAg expression and immune ...
Chunting Zhu, Jie Yang, Yu Sheng, Min Fang   +3 more
doaj   +2 more sources

Viral vector- and virus-like particle-based vaccines against infectious diseases: A minireview

Heliyon
To overcome the limitations of conventional vaccines, new platforms for vaccine design have emerged such as those based on viral vectors and virus-like particles (VLPs).
Ruth Henríquez, Isabel Muñoz-Barroso
doaj   +3 more sources

Hepatitis Vaccines: Recent Advances and Challenges [PDF]

Vaccines
Viral hepatitis constitutes a substantial global public health challenge. The etiological agents, referred to as hepatitis viruses, are primarily categorized into five types: hepatitis A virus (HAV), hepatitis B virus (HBV), hepatitis C virus (HCV ...
Mei Lu, Yakun Liu, Lele Li, Xueke Liu, Bin Wu, Yingping Wu   +5 more
doaj   +2 more sources

Phylodynamic Analysis Suggests That Deer Species May Be a True Reservoir for Hepatitis E Virus Genotypes 3 and 4

Microorganisms, 2023
Hepatitis E virus (HEV) genotypes 3 and 4 (HEV-3 and HEV-4) cause zoonotic infection in humans, with domestic pigs and wild boars being the main reservoirs of infection.
Anastasia A. Karlsen, Vera S. Kichatova, Karen K. Kyuregyan, Mikhail I. Mikhailov   +3 more
doaj   +1 more source

Coverage with Timely Administered Vaccination against Hepatitis B Virus and Its Influence on the Prevalence of HBV Infection in the Regions of Different Endemicity

Vaccines, 2021
Universal hepatitis B vaccination of newborns was implemented in Russia starting from 1998. From 1998 to 2019, the incidence of acute hepatitis B reduced from 43.8 to 0.57 cases per 100,000 population.
Karen K. Kyuregyan, Vera S. Kichatova, Olga V. Isaeva, Ilya A. Potemkin, Elena Yu. Malinnikova, Maria A. Lopatukhina, Anastasia A. Karlsen, Fedor A. Asadi Mobarhan, Eugeniy V. Mullin, Olga S. Slukinova, Margarita E. Ignateva, Snezhana S. Sleptsova, Elena E. Oglezneva, Elena V. Shibrik, Maria G. Isaguliants, Mikhail I. Mikhailov   +15 more
doaj   +1 more source

Geographic and Temporal Variability of Hepatitis E Virus Circulation in the Russian Federation

Viruses, 2022
The factors influencing hepatitis E virus (HEV) circulation remain largely unexplored. We investigated HEV seroprevalence in humans and the prevalence of infection in farm pigs and rabbits in different regions of the Russian Federation, as well as the ...
Mikhail I. Mikhailov, Anastasia A. Karlsen, Ilya A. Potemkin, Olga V. Isaeva, Vera S. Kichatova, Elena Yu. Malinnikova, Fedor A. Asadi Mobarkhan, Eugeniy V. Mullin, Maria A. Lopatukhina, Victor A. Manuylov, Elena P. Mazunina, Evgeniia N. Bykonia, Denis A. Kleymenov, Liubov I. Popova, Vladimir A. Gushchin, Artem P. Tkachuk, Andrey D. Polyakov, Ahmed Mohammed Eladly, Sergey A. Solonin, Ilya V. Gordeychuk, Karen K. Kyuregyan   +20 more
doaj   +1 more source

Dynamic Changes in Hepatitis A Immunity in Regions with Different Vaccination Strategies and Different Vaccination Coverage

Vaccines, 2022
The data on hepatitis A virus (HAV) seroprevalence are critical for the implementation of a universal mass vaccination (UMV) strategy. The latter has not been implemented in Russia; however, regional child vaccination programs have been adopted in some ...
Karen K. Kyuregyan, Maria A. Lopatukhina, Fedor A. Asadi Mobarkhan, Vera S. Kichatova, Ilya A. Potemkin, Olga V. Isaeva, Anastasia A. Karlsen, Elena Yu. Malinnikova, Alla N. Kaira, Tatyana V. Kozhanova, Victor A. Manuylov, Elena P. Mazunina, Evgeniia N. Bykonia, Denis A. Kleymenov, Margarita E. Ignateva, Olga E. Trotsenko, Anna V. Kuznetsova, Anna A. Saryglar, Natalia D. Oorzhak, Victor V. Romanenko, Mikhail I. Mikhailov   +20 more
doaj   +1 more source

Transfusion Transmissible Infections in Blood Donors in the Province of Bié, Angola, during a 15-Year Follow-Up, Imply the Need for Pathogen Reduction Technologies

Pathogens, 2021
Transfusion transmissible infections (TTIs), caused by hepatitis B virus (HBV), human immunode-ficiency virus (HIV), hepatitis C virus (HCV), and syphilis, have a high global impact, especially in sub-Saharan Africa.
Luis Baião Peliganga, Vinicius Motta Mello, Paulo Sergio Fonseca de Sousa, Marco Aurelio Pereira Horta, Álvaro Domingos Soares, João Pedro da Silva Nunes, Miguel Nobrega, Lia Laura Lewis-Ximenez   +7 more
doaj   +1 more source