Results 41 to 50 of about 57,071 (293)

Structural Vaccinology for Viral Vaccine Design

open access: yesFrontiers in Microbiology, 2019
Although vaccines have proven pivotal against arrays of infectious viral diseases, there are still no effective vaccines against many viruses. New structural insights into the viral envelope, protein conformation, and antigenic epitopes can guide the ...
Mohd Ishtiaq Anasir, Chit Laa Poh
doaj   +1 more source

Antiviral activity of zinc against hepatitis viruses: current status and future prospects

open access: yesFrontiers in Microbiology, 2023
Viral hepatitis is a major public health concern globally. World health organization aims at eliminating viral hepatitis as a public health threat by 2030.
Shiv Kumar   +4 more
doaj   +1 more source

Viral hepatitis

open access: yesSouth African Family Practice, 2006
The hepatitis A, B, C, D and E viruses primarily target the liver to cause viral hepatitis. Hepatitis A (HAV) and E (HEV) viruses are transmitted by the faecal-oral route and cause acute viral hepatitis.
D. Brink
doaj   +1 more source

Potential of CRISPR/Cas system as emerging tools in the detection of viral hepatitis infection

open access: yesVirology Journal, 2023
Viral hepatitis, the most common cause of inflammatory liver disease, affects hundreds of millions of people worldwide. It is most commonly associated with one of the five nominal hepatitis viruses (hepatitis A–E viruses).
Howra Bahrulolum   +6 more
doaj   +1 more source

Virus-like Particle Vaccines and Platforms for Vaccine Development

open access: yes, 2023
Virus-like particles (VLPs) have gained a lot of interest within the past two decades. The use of VLP-based vaccines to protect against three infectious agents—hepatitis B virus, human papillomavirus, and hepatitis E virus—has been approved ...
Hong Liu   +2 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Coronavirus non-structural protein 1 is a major pathogenicity factor : implications for the rational design of coronavirus vaccines

open access: yes, 2007
Zust, Roland Cervantes-Barragan, Luisa Kuri, Thomas Blakqori, Gjon Weber, Friedemann Ludewig, Burkhard Thiel, Volker 5 R21 AI062246/AI/United States NIAID Research Support, N.I.H., Extramural Research Support, Non-U.S.
Thiel Volker   +26 more
core   +1 more source

Predictions of the emergence of vaccine-resistant hepatitis B in The Gambia using a mathematical model [PDF]

open access: yes, 2000
Vaccine escape variants of hepatitis B virus (HBV) have been identified world-wide. A mathematical model of HBV transmission is used to investigate the potential pattern of emergence of such variants.
Wilson, J. N.   +2 more
core   +1 more source

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

open access: yesAdvanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang   +10 more
wiley   +1 more source

Development of polyepitopic immunogenic contrast against hepatitis C virus 1a-6a genotype by in silico approach

open access: yesBiomedical and Biotechnology Research Journal, 2020
Background: Hepatitis C is a viral disease associated with chronic hepatitis and hepatocellular carcinoma. Hepatitis C virus (HCV) plays a critical role in the pathogenesis of this disease.
Zeinab Dehghan   +6 more
doaj   +1 more source

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