Results 11 to 20 of about 299,195 (309)

Research progress of therapeutic vaccines for treating chronic hepatitis B

Human Vaccines & Immunotherapeutics, 2017
Hepatitis B virus (HBV) is a member of Hepadnavirus family, which leads to chronic infection in around 5% of patients with a high risk of developing liver cirrhosis, liver failure, and hepatocellular carcinoma.
Jianqiang Li, Mengru Bao, Jun Ge, Sulin Ren, Tong Zhou, Fengchun Qi, Xiuying Pu, Jia Dou   +7 more
doaj   +2 more sources

TLR agonists as vaccine adjuvants in the prevention of viral infections: an overview

Frontiers in Microbiology, 2023
Tol-like receptor (TLR) agonists, as potent adjuvants, have gained attention in vaccine research for their ability to enhance immune responses. This study focuses on their application in improving vaccine efficacy against key viral infections, including ...
Mohammad Enamul Hoque Kayesh, Michinori Kohara, Kyoko Tsukiyama-Kohara   +2 more
doaj   +2 more sources

Vaccines for neonatal viral infections: Hepatitis B vaccine

Expert Review of Vaccines, 2004
In many parts of the world, intervention in the neonatal period is required for prevention of hepatitis B virus infection and its consequences.
F T, Cutts, A J, Hall
openaire   +3 more sources

Viral evasion and challenges of hepatitis C virus vaccine development [PDF]

Current Opinion in Virology, 2016
Hepatitis C virus (HCV) is a major global disease burden, often leading to chronic liver diseases, cirrhosis, cancer, and death in those infected. Despite the recent approval of antiviral therapeutics, a preventative vaccine is recognized as the most effective means to control HCV globally, particularly in at-risk and developing country populations ...
Brian G, Pierce, Zhen-Yong, Keck, Steven Kh, Foung   +2 more
openaire   +3 more sources

Features of Effective T Cell-Inducing Vaccines against Chronic Viral Infections

Frontiers in Immunology, 2018
For many years, the focus of prophylactic vaccines was to elicit neutralizing antibodies, but it has become increasingly evident that T cell-mediated immunity plays a central role in controlling persistent viral infections such as with human ...
Eleni Panagioti, Eleni Panagioti, Paul Klenerman, Lian N. Lee, Sjoerd H. van der Burg, Ramon Arens   +5 more
doaj   +2 more sources

The global burden of viral hepatitis from 1990 to 2013: findings from the Global Burden of Disease Study 2013.

Lancet, The, 2016
J. Stanaway, A. Flaxman, M. Naghavi, C. Fitzmaurice, T. Vos, I. Abubakar, L. Abu-Raddad, R. Assadi, N. Bhala, B. Cowie, Mohammad H. Forouzanfour, Justina Groeger, Khayriyyah Mohd Hanafiah, K. Jacobsen, S. James, J. MacLachlan, R. Malekzadeh, N. Martin, A. A. Mokdad, A. Mokdad, C. Murray, D. Plass, S. Rana, David B. Rein, J. Richardus, J. Sanabria, M. Saylan, S. Shahraz, S. So, V. Vlassov, E. Weiderpass, S. Wiersma, M. Younis, Chuanhua Yu, M. El Sayed Zaki, G. Cooke   +35 more
semanticscholar   +3 more sources

Phylodynamic Analysis Suggests That Deer Species May Be a True Reservoir for Hepatitis E Virus Genotypes 3 and 4

Microorganisms, 2023
Hepatitis E virus (HEV) genotypes 3 and 4 (HEV-3 and HEV-4) cause zoonotic infection in humans, with domestic pigs and wild boars being the main reservoirs of infection.
Anastasia A. Karlsen, Vera S. Kichatova, Karen K. Kyuregyan, Mikhail I. Mikhailov   +3 more
doaj   +1 more source

Influenza nucleoprotein delivered with aluminium salts protects mice from an influenza virus that expresses an altered nucleoprotein sequence [PDF]

, 2013
Influenza virus poses a difficult challenge for protective immunity. This virus is adept at altering its surface proteins, the proteins that are the targets of neutralizing antibody.
A Endo, A Portela, AJ McMichael, Alexandria David, Andrew Pekosz, AS McKee, AT Heiny, B Zhou, CJ Wei, CS Ambrose, D Corti, D Grimm, D Zehn, DM Carragher, DT O’Hagan, E de Wit, F Crawford, F Rahman, GA Poland, GE Price, GT Belz, H Hikono, H Hohn, JB Ulmer, JE McElhaney, Jieru Wang, John W. Kappler, JP Christensen, JW Yewdell, K Thueng-in, L Guo, Laura Noges, LE Brown, LL Shu, M Schotsaert, M Wang, Megan K. L. MacLeod, MK MacLeod, MM Cox, MW LaMere, MW Lamere, N Garcon, Niyun Jin, P Marrack, Philippa Marrack, R Sebastian, RA Medina, SL Giannini, T Lambe, TM Wilkinson, U Kees, Y Furuya   +51 more
core   +28 more sources

Coverage with Timely Administered Vaccination against Hepatitis B Virus and Its Influence on the Prevalence of HBV Infection in the Regions of Different Endemicity

Vaccines, 2021
Universal hepatitis B vaccination of newborns was implemented in Russia starting from 1998. From 1998 to 2019, the incidence of acute hepatitis B reduced from 43.8 to 0.57 cases per 100,000 population.
Karen K. Kyuregyan, Vera S. Kichatova, Olga V. Isaeva, Ilya A. Potemkin, Elena Yu. Malinnikova, Maria A. Lopatukhina, Anastasia A. Karlsen, Fedor A. Asadi Mobarhan, Eugeniy V. Mullin, Olga S. Slukinova, Margarita E. Ignateva, Snezhana S. Sleptsova, Elena E. Oglezneva, Elena V. Shibrik, Maria G. Isaguliants, Mikhail I. Mikhailov   +15 more
doaj   +1 more source

Geographic and Temporal Variability of Hepatitis E Virus Circulation in the Russian Federation

Viruses, 2022
The factors influencing hepatitis E virus (HEV) circulation remain largely unexplored. We investigated HEV seroprevalence in humans and the prevalence of infection in farm pigs and rabbits in different regions of the Russian Federation, as well as the ...
Mikhail I. Mikhailov, Anastasia A. Karlsen, Ilya A. Potemkin, Olga V. Isaeva, Vera S. Kichatova, Elena Yu. Malinnikova, Fedor A. Asadi Mobarkhan, Eugeniy V. Mullin, Maria A. Lopatukhina, Victor A. Manuylov, Elena P. Mazunina, Evgeniia N. Bykonia, Denis A. Kleymenov, Liubov I. Popova, Vladimir A. Gushchin, Artem P. Tkachuk, Andrey D. Polyakov, Ahmed Mohammed Eladly, Sergey A. Solonin, Ilya V. Gordeychuk, Karen K. Kyuregyan   +20 more
doaj   +1 more source