Results 181 to 190 of about 131,813 (277)

Geographic and Temporal Variations in Immunization Coverage in Nepal: An Ecological Time‐Trend Analysis

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Immunization remains a vital public health intervention in Nepal, yet significant disparities persist. This study evaluates the performance of Nepal's national immunization program by analyzing district‐level vaccination coverage and dropout rates from 2009 to 2022 to identify trends and disparities across different routine ...
Kritika Rana, Supreme Raj Pandey, Romila Chimoriya, Prakash Poudel, Bhupendra Man Singh Shrestha, Sandeep Kumar Okheda, Ritesh Chimoriya   +6 more
wiley   +1 more source

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

Transfusion, EarlyView.
Thane Kubik, Theodros Mamo, David H. McKenna   +2 more
wiley   +1 more source

Association Between Polymorphisms rs11003125 and rs7096206 of the MBL2 Gene and the Stages of Hepatitis B Progression in Burkina Faso: A Comparative Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Objectives Hepatitis B virus (HBV) infection remains a major global health burden, with disease progression influenced by host genetic and immune factors, including variants in the mannose‐binding lectin 2 (MBL2) gene. This study aimed to evaluate the association between MBL2 polymorphisms and clinical outcomes of HBV infection ...
Minane Nafissa Triande, Lassina Traore, Sidnooma Véronique Zongo, Teega‐Wendé Clarisse Ouedraogo, Mousso Savadogo, Sanata Nadine Kiemde, Tegwindé Rébéca Compaore, Augustin Tozoula Bambara, Roger Arsène Sombie, Patoinewendé Denise Ilboudo, Albert Théophane Yonli, Bolni Marius Nagalo, Florencia Wendkuuni Djigma, Jacques Simpore   +13 more
wiley   +1 more source

Vaccination and transfusion safety at the time of expanding use of live attenuated vaccines

Vox Sanguinis, EarlyView.
Pierre Tiberghien, Pierre Gallian, Virginie de La Taille, Caroline Bacquet, Syria Laperche   +4 more
wiley   +1 more source

Whispers of Pathogens; Social Contagion in Infectious Disease Dynamics: A Review

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Infectious disease dynamics are deeply intertwined with social structures, behaviors, and information systems. This narrative review examines how social factors conceptualized through the integrated lens of “social contagion” within a syndemic framework shape infectious disease patterns from January 2000 to January 2024 ...
Sayed Mortaza Fayez
wiley   +1 more source

Predicting optimal impact interventions in the post‐HPV vaccination world

International Journal of Cancer, Volume 158, Issue 9, Page 2262-2271, 1 May 2026.
Abstract Prophylactic vaccination is a powerful tool that changes exposure to infections and associated morbidity of preventable diseases. We discuss the impact of pneumococci and human papillomavirus (HPV) vaccination on the population biology of the two micro‐organisms and related public health effects.
Matti Lehtinen, Marc Lipsitch, Ville N. Pimenoff, Karin Sundström, Johannes Berkhof, Iacopo Baussano, Simopekka Vänskä, Joakim Dillner   +7 more
wiley   +1 more source

Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications

MedComm, Volume 7, Issue 5, May 2026.
Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang, Xiaoqing Wang, Kai Luo, Tikam Chand Dakal, He Bai, Caiming Xu, Guixin Zhang   +6 more
wiley   +1 more source

Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy

MedComm, Volume 7, Issue 5, May 2026.
Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley   +1 more source

The EUROmediCAT Network and Databases: A Resource for Pharmacovigilance in Pregnancy

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 5, May 2026.
ABSTRACT Background The evidence gap relating to the risk of congenital anomalies (CA) associated with first trimester medication exposure in pregnancy is well recognized. Aims We describe the EUROmediCAT network and databases, and the methodological approach to pregnancy pharmacovigilance.
Helen Dolk, Christine Damase‐Michel, Joan Morris, Amanda Neville, Ester Garne, Sue Jordan, Anke Rissmann, Alessio Coi, Deirdre Folan, Dieuwke Broekstra, Jennifer M. Broughan, Lea Bruneau, Clara Cavero‐Carbonell, Elly den Hond, Miriam Gatt, Mika Gissler, Babak Khoshnood, Anna Latos Bielenska, Hedvig Nordeng, Ljubica Odak, Mary O'Mahony, Isabelle Perthus, J. Luke Richardson, Florence Rouget, Joanna Sichitiu, David Tucker, Natalya Zymak‐Zakutnya, Maria Loane   +27 more
wiley   +1 more source

The Management of Congenital Cytomegalovirus Infection in an Era of Universal Newborn CMV Screening

Reviews in Medical Virology, Volume 36, Issue 3, May 2026.
ABSTRACT The most common infectious disease responsible for paediatric developmental disability is congenital infection with human cytomegalovirus (cCMV). Many serious sequelae are caused by cCMV, including microcephaly, intracranial calcifications, neuronal migration defects, seizure disorders, developmental delay, and sensorineural hearing loss (SNHL)
Emily R. Harrison, W. Charles Huskins, Mark R. Schleiss   +2 more
wiley   +1 more source