Results 211 to 220 of about 80,496 (306)

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, Volume 13, Issue 35, 24 June 2026.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

Neurocognitive Aging Following Acute Illness: Pathobiology and a Framework for Developing Neurotherapeutic Agents

open access: yesBrain and Behavior, Volume 16, Issue 6, June 2026.
In this review, we discuss the scientific basis for how neurocognitive aging occurs after critical illness, including sepsis, trauma, and burns, and the clinical need to develop therapies to reduce inflammation, protect the blood–brain barrier, remove senescent cells, and enhance neuroplasticity.
Errin Lawrence   +14 more
wiley   +1 more source

Long-Term Persistence of Hepatitis A Virus Immunity in Healthcare Workers Upto 25 Years After Vaccination. [PDF]

open access: yesJ Viral Hepat
Noviello C   +11 more
europepmc   +1 more source

Immunogenic Cell Death: Unlocking New Frontiers in Cancer Immunotherapy

open access: yesCancer Innovation, Volume 5, Issue 3, June 2026.
Immunogenic cell death ICD is a specific type of stress‐induced cell death that results in adaptive immune response and generating an immunological memory. The development of strategies that induce ICD are considered highly effective in the treatment of cancer within the bounds of immunotherapy.
Katherine Yaacoub
wiley   +1 more source

Isoniazid‐Related Secondary Drug‐Induced Autoimmune Hepatitis in a Patient Diagnosed With Ankylosing Spondylitis and Tuberculous Lymphadenitis: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Autoimmune hepatitis is a type of chronic hepatitis that is usually progressive, has unknown etiology, and can occur at any age. In the present case, drug‐associated autoimmune hepatitis (DIAIH) was discussed, and DIAIH secondary to isoniazid (INH) was found in two case reports in the literature.
Murat AY, Erhan Bozkurt
wiley   +1 more source

Hepatitis E vaccines

open access: yes, 2008
Robert H. Purcell, Suzanne U. Emerson
openaire   +1 more source

Co‐infection of Hepatitis A and E With Atypical Manifestation: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Hepatitis A virus (HAV) and hepatitis E virus (HEV) are common causes of acute viral hepatitis in developing countries where inadequate sanitation and contaminated water supplies facilitate fecal–oral transmission. Although both infections are usually self‐limiting, co‐infection may result in atypical presentations and pose diagnostic ...
Umaimah Batool Mirza   +4 more
wiley   +1 more source

Brief Report: Hepatitis B Vaccination Histories in Persons With HIV Needing Revaccination. [PDF]

open access: yesJ Acquir Immune Defic Syndr
Kang M   +10 more
europepmc   +1 more source

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