Advanced Science, EarlyView.Calhm6 drives M2 macrophage polarization via the Chp1‐Camk4‐Creb1 axis, suppressing inflammation through calcium‐dependent ectosomal delivery. Calhm6 deficiency enhances M1 responses, boosting bactericidal activity but exacerbating tissue damage. LPS/IFNγ upregulate Calhm6 via Irf1, while IL‐4/Stat6 inhibits it, balancing immune outcomes.
Yanlong Xin +14 more
wiley +1 more source
Revista do Instituto de Medicina Tropical de São Paulo, 1989 Schedule for vaccination against HBV infection has usually been based on three separate injections of 20 meg of the vaccine by intramuscular route. One of the main shortcomings to its use in large scale programs has been its high cost.
Flair José Carrilho +6 more
doaj +1 more source
Viral hepatitis is a term commonly used for several clinically similar yet etiologically and epidemiologically distinct diseases. Hepatitis A (formerly called infectious hepatitis) and hepatitis B (formerly called serum hepatitis) have been recognized as
Hepatitis B
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The Iowa Viral Hepatitis Strategic Plan 2012-2016, August 26, 2014 [PDF]
, 2014 Since the creation of the first viral hepatitis plan in 2004 several documents and advancements have been released that help Iowa plan and prioritize this revision of our hepatitis plan.
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CircSMEK1 Suppresses HCC via the hnRNPK‐IGF2‐AKT Axis: A Diagnostic Biomarker and Therapeutic Target
Advanced Science, EarlyView.CircSMEK1 is downregulated in MASH/HCC and predicts poor prognosis. It suppresses tumor progression by promoting hnRNPK ubiquitination and inhibiting the IGF2/PI3K/AKT axis, while its loss activates immunosuppressive cancer‐associated fibroblasts. Serum circSMEK1 serves as a non‐invasive diagnostic biomarker, and its restoration potently inhibits HCC ...
Peilan Guo +15 more
wiley +1 more source
Polymorphisms in XRCC1 and Glutathione S-Transferase Genes and Hepatitis B-Related Hepatocellular Carcinoma [PDF]
, 2003 Ming‐Whei Yu +9 more
openalex +1 more source
Advanced Science, EarlyView.Hepatocyte‐derived extracellular vesicles deliver miR‐328‐3p to trigger PP2A‐B56δ–mediated p‐NLRP3S295‐dependent metaflammation in macrophages upon microcystin‐LR exposure. 2‐DG, 2‐deoxy‐D‐glucose. B56δ, protein phosphatase 2A‐B56δ. ER, endoplasmic reticulum. iHD‐EV, inducible hepatocyte‐derived extracellular vesicles. IP3R, inositol 1,4,5‐triphosphate
Jia‐Shen Wu +13 more
wiley +1 more source
Hepatitis B Vaccination Coverage among Healthcare Workers and Evaluation of Immune Response by Estimating Anti-HBs Antibody Titers over Time at a Tertiary Care Hospital: A Cross-sectional Study [PDF]
Journal of Clinical and Diagnostic ResearchIntroduction: Healthcare Workers (HCWs) are at a high-risk of acquiring Hepatitis B Virus (HBV) infection. However, this risk can be prevented through Hepatitis B vaccination.
PRIYANKA SONI +6 more
doaj +1 more source
Frequency of hepatitis D virus infection in individuals with hepatitis B surface antigen-positive (HBS Ag) in Ardabil province [PDF]
Frequency of hepatitis D virus infection in individuals with hepatitis B surface antigen-positive (HBS Ag) in Ardabil province Introduction: hepatitis D virus (HDV) and hepatitis B virus (HBV)co-infection is well known to induce a spectrum of acute ...
امانی, فیروز +2 more
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Hepatitis B Virus Reactivation in Patients Receiving Interferon-Free Direct-Acting Antiviral Agents for Chronic Hepatitis C Virus Infection [PDF]
, 2017 Chen‐Hua Liu +7 more
openalex +1 more source