Results 181 to 190 of about 184,721 (306)

Real‐world efficacy and toxicity of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma according to IMDC risk criteria—A multi‐center retrospective analysis on behalf of the GUARDIANS group

open access: yesInternational Journal of Cancer, EarlyView.
What's New? The combination of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma has demonstrated durable response and tolerability in clinical trials. However, inclusion criteria for clinical studies are restrictive, and patients in the real‐world setting tend to have more comorbidities.
Hendrik Dinkel   +21 more
wiley   +1 more source

A mouse hybridoma cell line secreting igg and igm antibodies with specificity for the hepatitis b virus surface antigen

open access: green, 1993
Giuvel Fontirrochi   +7 more
openalex   +1 more source

Exercise serum promotes DNA damage repair and remodels gene expression in colon cancer cells

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Exercise releases bioactive molecules into the bloodstream that can directly slow cancer cell growth. In colon cancer, this may help limit disease progression. Here, using colon cancer cells, the authors investigated the effects of exercise‐conditioned human serum on DNA repair mechanisms. Notably, acute exercise in humans elicited systemic
Samuel T. Orange   +9 more
wiley   +1 more source

Intermittent loss of anti-HBc antibodies in people with multiple sclerosis undergoing disease-modifying therapies. [PDF]

open access: yesBMC Infect Dis
Pasculli P   +12 more
europepmc   +1 more source

PD‐1/PD‐L1 in Hepatocellular Carcinoma (2014–2024): A Combined Macro and Micro Analysis of Immunotherapy Implications

open access: yesiNew Medicine, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) represents a significant global health issue, with the PD‐1/PD‐L1 axis serving a pivotal target for immunotherapy in this malignancy. However, a comprehensive bibliometric analysis of PD‐1/PD‐L1 research in HCC is lacking.
Xingyu Zhu   +4 more
wiley   +1 more source

Tenofovir alafenamide for prevention of HBV reactivation in HBsAg-negative, anti-HBc-positive patients undergoing rituximab-based chemotherapy: A multicenter randomized controlled trial. [PDF]

open access: yesHepatol Commun
Tabataba Vakili S   +19 more
europepmc   +1 more source

Fertility and Early Embryonic Development Toxicity of hzVSF‐v13 in Sprague–Dawley Rats

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Humanized virus suppressing factor–variant 13 (hzVSF‐v13), a monoclonal IgG4 antibody, is a potential therapeutic candidate for COVID‐19. Although fertility and embryonic developmental toxicity studies are crucial for the safety evaluation of new drugs, the toxicological profile of hzVSF‐v13 remains unexplored.
Ji‐Seong Jeong   +10 more
wiley   +1 more source

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