Results 91 to 100 of about 281,611 (124)

Markers for internal neoplasia in the horse

Veterinary Medicine and Science, Volume 9, Issue 1, Page 132-143, January 2023., 2023
The measurement of tumour markers in horses should be performed only in risk groups or in patients with suspicious clinical/laboratory findings (paraneoplastic syndromes). The results should be interpreted with caution as many factors (e.g., young age, pregnancy and inflammation) affect their concentration or activity.
Karolina Drozdzewska, Heidrun Gehlen
wiley   +1 more source

Human sporadic breast carcinoma histotypes driven by the Human Betaretrovirus homologous to Mouse Mammary Tumor Virus

International Journal of Cancer, EarlyView.
What's New? While estrogens, obesity, and alcohol are recognized risk factors for breast cancer, a viral hypothesis has been suggested based on the murine model of Mouse Mammary Tumor Virus (MMTV)‐induced mammary tumors. This study analyzed sequences of the human homolog of MMTV across human breast carcinoma histotypes, detecting the virus in all types
Prospero Civita, Chiara Maria Mazzanti, Francesca Lessi, Caterina Marchiò, Cristian Scatena, Michele Menicagli, Matteo Ghilli, Manuela Roncella, Antonio Giuseppe Naccarato, Anna Sapino, Jacob Hochman, Mauro Pistello, Generoso Bevilacqua   +12 more
wiley   +1 more source

Racing toward the future of chronic hepatitis B management: Achieving functional cure and enhancing hepatocellular carcinoma surveillance through precision medicine

Interdisciplinary Medicine, EarlyView.
Novel biomarker emergence plays a critical role in improving CHB management. Advances in sensitive detection methods, AI, and large‐scale data platforms have independently contributed to biomarkers while driving the development of multi‐omics approaches.
Yaru Shi, Rong Fan
wiley   +1 more source

Roles of nanomagnetic beads on biosensing: From fabrication to application

Interdisciplinary Medicine, EarlyView.
Leveraging their intrinsic superparamagnetic properties and rapid magnetic responsiveness, functionalized nanomagnetic beads have emerged as pivotal platforms in advanced biosensing system. Through surface engineering and structural design, these magnetic nanoparticles demonstrate multi‐capabilities, such as sample separation, signal enhancement, and ...
Junjie Li, Liyang Duan, Qian Chen, Songsong Huang, Weixia Li, Huachu Zuo, Shuang Li, Wei Han, Wei Fu, Shike Hou, Bin Fan, Zetao Chen   +11 more
wiley   +1 more source

A Large‐Scale Retrospective Study of Serum Des‐Gamma‐Carboxy Prothrombin as a Diagnostic Marker of HCC: Effect of Liver Function on Specificity

Journal of Clinical Laboratory Analysis, EarlyView.
Serum DCP may serve as an optimal biomarker for the diagnosis of HCC, but its accuracy appears to be influenced by liver function. The serum DCP may also serve as a biomarker for liver resection and interventional therapy of HCC, but is not promising for systemic treatment. ABSTRACT Background This retrospective multicenter study is aimed at evaluating
Hongying Bu, Weijia Luo, Wenli Tao, Chen Dong, Meifang Wang, Xu Ye, Xi Zeng, Boqing Wang, Chang Liu, Qi Yu, Deliang Cao, Hongyu Deng, Yuemin Nan   +12 more
wiley   +1 more source

Diagnostic Value of Serum Cytokeratin 18 for the Staging of Liver Inflammation and Fibrosis: A Meta‐Analysis

Journal of Clinical Laboratory Analysis, EarlyView.
The cytokeratin 18 (CK18) test has been served as the non‐invasive assessment to detect nonalcoholic steatohepatitis and fibrosis. We performed a meta‐analysis to evaluate the accuracy of CK18 against a liver biopsy in adults. Serum CK18 had moderate diagnostic value in different stages of liver fibrosis and significant inflammation, which may serve as
Jinwen Chen, Jian Hu, Jialin Zhuang, Zhong Li, Se Peng, Xiaoting Huang, Jialing Zhuang   +6 more
wiley   +1 more source

Efanesoctocog Alfa Population Pharmacokinetics and Repeated Time‐To‐Event Analysis of Bleeds in Adults, Adolescents, and Children with Severe Hemophilia A

The Journal of Clinical Pharmacology, EarlyView.
Abstract Efanesoctocog alfa is a first‐in‐class high‐sustained factor VIII (HSF) replacement therapy for treatment of hemophilia A. This article presents population pharmacokinetics (PopPK) of efanesoctocog alfa and repeated time‐to‐event (RTTE) analysis of bleeding episodes in adults/adolescents (≥12 years of age) and children (<12 years).
Nancy Wong, Pratik Bhagunde, Joakim Nyberg, Suresh Katragadda, Marek Demissie, Annemieke Willemze, Craig Benson, Sreeraj Macha   +7 more
wiley   +1 more source

Integrated gross and microanatomical analysis of the periportal lymphatic system in human liver

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
Abstract Background Although animal studies have indicated that the periportal lymphatic system is an important intrahepatic lymphatic route, detailed human studies are scarce. We studied the lymphatic pathways and dynamics around Glisson's capsule in human livers. Methods We performed whole‐mount immunostaining for the liver using podoplanin and CD‐31
Yuto Mitsuhashi, Hiroshi Shimoda, Kotaro Umemura, Takuji Kagiya, Kentaro Sato, Hirokazu Narita, Tomohiro Chiba, Keinosuke Ishido, Norihisa Kimura, Kenichi Hakamada   +9 more
wiley   +1 more source

Trends in resource utilization for new‐onset psychosis hospitalizations at children's hospitals

Journal of Hospital Medicine, EarlyView.
Abstract Background Children with new‐onset psychosis often require hospitalization for medical evaluation. Objectives The goal of this study was to assess variations in the management of children with new‐onset psychosis and characterize trends in resource utilization.
Ankita Gupta, Matt Hall, Benjamin Masserano, Averi Wilson, Katherine Johnson, Clifford Chen, Lasya Challa, Harita Katragadda, Vineeta Mittal   +8 more
wiley   +1 more source

Practices of North American pediatric gastroenterologists in the management of celiac disease—A survey study

JPGN Reports, EarlyView.
Abstract Celiac disease (CD) is a common autoimmune disorder characterized by an immune‐mediated reaction to gluten. We conducted a survey study of the pediatric gastroenterology list server to assess the practices of North American pediatric gastroenterologists in the management of CD. Overall, 160 out of 2400 respondents participated in the study, of
Hamza Hassan Khan, Sanjay Kumar, Hernando Lyons   +2 more
wiley   +1 more source