Results 11 to 20 of about 148,115 (259)

Blocking entry of hepatitis B and D viruses to hepatocytes as a novel immunotherapy for treating chronic infections [PDF]

open access: yes, 2021
Background. Chronic hepatitis B and D virus (HBV/HDV) infections can cause cancer. Current HBV therapy using nucleoside analogues (NAs) is life-long and reduces but does not eliminate the risk of cancer.
Ahlén, G   +13 more
core   +1 more source

Modulation of antigen-specific T-cells as immune therapy for chronic infectious diseases and cancer [PDF]

open access: yes, 2014
Copyright: © 2014 Li, Symonds, Miao, Sanderson and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Abraham   +55 more
core   +6 more sources

Tumour antigen expression in hepatocellular carcinoma in a low-endemic western area [PDF]

open access: yes, 2015
Background: Identification of tumour antigens is crucial for the development of vaccination strategies against hepatocellular carcinoma (HCC). Most studies come from eastern-Asia, where hepatitis-B is the main cause of HCC.
A Ferrandez-Izquierdo   +90 more
core   +5 more sources

MAIT cells come to the rescue in cancer immunotherapy? [PDF]

open access: yes, 2020
Recent progress in immunobiology has led to the observation that, among cells classically categorized as the typical representatives of the adaptive immune system, i.e., T cells, some possess the phenotype of innate cells.
Elewaut, Dirk   +2 more
core   +2 more sources

Assessment of the cross-protective capability of recombinant capsid proteins derived from pig, rat, and avian hepatitis E viruses (HEV) against challenge with a genotype 3 HEV in pigs [PDF]

open access: yes, 2012
Hepatitis E virus (HEV), the causative agent of hepatitis E, is primarily transmitted via the fecal-oral route through contaminated water supplies, although many sporadic cases of hepatitis E are transmitted zoonotically via direct contact with infected ...
Córdoba, Laura   +5 more
core   +1 more source

Modulation of the CD8+-T-cell response by CD4+ CD25+ regulatory T cells in patients with Hepatitis B virus infection [PDF]

open access: yes, 2005
CD4+ CD25+ regulatory T cells have been shown to maintain peripheral tolerance against self and foreign antigens. In this study we analyzed the effect of circulating CD4+ CD25+ T cells on CD8+-T-cell responses of patients with chronic and resolved ...
Bertoletti, A.   +6 more
core   +2 more sources

Fighting viral infections and virus-driven tumors with cytotoxic CD4+ T cells [PDF]

open access: yes, 2017
CD4+ T cells have been and are still largely regarded as the orchestrators of immune responses, being able to differentiate into distinct T helper cell populations based on differentiation signals, transcription factor expression, cytokine secretion, and
Adhikary   +229 more
core   +2 more sources

Hepatitis B Antigen in Saliva

open access: yesThe Tohoku Journal of Experimental Medicine, 1973
Hepatitis B antigen (HB Ag) detectable only by means of rvdioimmnnoassay was found in saliva of 5 out of 36 mentally retarded children in an institution. Electron microscopic study of purified antigen in saliva revealed the presence of tubular and small Dane particles.
Shinobu Matsuda   +5 more
openaire   +4 more sources

Hepatitis B Core-Related Antigen and New Therapies for Hepatitis B [PDF]

open access: yesMicroorganisms, 2021
The hepatitis B core-related antigen (HBcrAg) is an unprecedented novel HBV biomarker that plays an essential role in reflecting covalently closed circular DNA (cccDNA) in chronic hepatitis B (CHB) because its levels correlate with intrahepatic cccDNA and serum HBV DNA.
Takehisa Watanabe   +2 more
openaire   +3 more sources

Apoptotic epitope-specific CD8+ T cells and interferon signaling intersect in chronic hepatitis C virus infection [PDF]

open access: yes, 2015
CD8(+) T cells specific to caspase-cleaved antigens derived from apoptotic T cells represent a principal player in chronic immune activation (CIA). Here, we found that both apoptotic epitope (AE)-specific and hepatitis C virus (HCV)-specific CD8(+) T ...
Accapezzato, Daniele   +18 more
core   +1 more source

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