Abstract Efanesoctocog alfa is a first‐in‐class high‐sustained factor VIII (HSF) replacement therapy for treatment of hemophilia A. This article presents population pharmacokinetics (PopPK) of efanesoctocog alfa and repeated time‐to‐event (RTTE) analysis of bleeding episodes in adults/adolescents (≥12 years of age) and children (<12 years).
Nancy Wong+7 more
wiley +1 more source
Glycoengineering of the hepatitis C virus E2 glycoprotein improves biochemical properties and enhances immunogenicity. [PDF]
Kulakova L+20 more
europepmc +1 more source
Integrated gross and microanatomical analysis of the periportal lymphatic system in human liver
Abstract Background Although animal studies have indicated that the periportal lymphatic system is an important intrahepatic lymphatic route, detailed human studies are scarce. We studied the lymphatic pathways and dynamics around Glisson's capsule in human livers. Methods We performed whole‐mount immunostaining for the liver using podoplanin and CD‐31
Yuto Mitsuhashi+9 more
wiley +1 more source
High prevalence of co-infections with latent tuberculosis, syphilis and hepatitis B and C among people with HIV in Ghana: a call for integrating screening into routine care. [PDF]
Lamptey H+14 more
europepmc +1 more source
Hepatitis B antigen in black patients with hepatocellular carcinoma.Correlation between orcein stained liver sections and serology [PDF]
Cynthia Cohen+2 more
openalex +1 more source
Trends in resource utilization for new‐onset psychosis hospitalizations at children's hospitals
Abstract Background Children with new‐onset psychosis often require hospitalization for medical evaluation. Objectives The goal of this study was to assess variations in the management of children with new‐onset psychosis and characterize trends in resource utilization.
Ankita Gupta+8 more
wiley +1 more source
Immunogenicity of an Intranasal Dual (Core and Surface)-Antigen Vaccine Against Hepatitis B Virus Enhanced by Carboxyl-Vinyl Polymer Excipients. [PDF]
Rashid MHO+15 more
europepmc +1 more source
Concentration and Purification of Hepatitis B Antigen with Polyethylene Glycol and Polyelectrolyte 60, a Cross-Linked Copolymer of Isobutylene Maleic Anhydride [PDF]
Edda de Rizzo+3 more
openalex +1 more source
Abstract Graft versus host disease (GVHD) is a complication that frequently occurs after haematopoietic stem cell transplantation and concerns many children in paediatric haematology‐oncology and bone marrow transplantation departments. It can affect various organs, with the skin, gastrointestinal tract and liver being the most commonly involved.
Marina Vincent+12 more
wiley +1 more source
Hepatitis B virus infection after immunization: How serious it is? An updated review. [PDF]
Marjani A+6 more
europepmc +1 more source