Results 271 to 280 of about 501,321 (365)

Exosome‐Based Theranostic for Gastrointestinal Cancer: Advances in Biomarker Discovery and Therapeutic Engineering

Small Methods, Volume 9, Issue 7, July 19, 2025.
This review explores the dual roles of exosomes in gastrointestinal (GI) cancers as diagnostic biomarkers and therapeutic agents. It highlights advancements in exosomal miRNAs, lncRNAs, circRNAs, and proteins for cancer detection and prognosis. The study also examines engineering strategies for exosome‐based drug delivery systems, their potential to ...
Mohit J. Mehta, Dongjun Shin, Hyun Sung Park, Jun Su An, Seong Il Lim, Hyun Jin Kim, Seungpyo Hong, Jiyoon Bu   +7 more
wiley   +1 more source

Humanized mouse model reveals the immunogenicity of Hepatitis B Virus vaccine candidates produced in CRISPR/Cas9-edited <i>Nicotiana benthamiana</i>. [PDF]

Front Immunol
Caras I, Ionescu IE, Pantazica AM, van Eerde A, Steen H, Heldal I, Haugslien S, Tucureanu C, Chelmus RE, Tofan VC, Costache A, Onu A, Su H, Branza-Nichita N, Liu-Clarke J, Stavaru C.   +15 more
europepmc   +1 more source

Plasma POSTN Derived From Bile Proteome Is a Promising Biomarker for Cholangiocarcinoma With Efficacy Comparable and Complementary to CA19.9

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background Cholangiocarcinoma presents a global health challenge due to its increasing incidence and poor prognosis, primarily resulting from delayed diagnosis. There is an urgent need for a reliable biomarker to enhance early detection. Materials and Methods Patients with cholangiocarcinoma were enrolled into three cohorts: a discovery set (n 
Lichieh Julie Chu, Chia‐Jung Tsai, Chun‐Chun Chien, Yung‐Chin Hsiao, Jau‐Song Yu, Jun‐Yi Tsai, Ta‐Sen Yeh   +6 more
wiley   +1 more source

Hepatitis B virus exposure among adolescents living with HIV: a cross-sectional study of samples referred to the national viral load and early infant diagnosis reference laboratory in Uganda. [PDF]

BMC Infect Dis
Turyamubona A, Muwanda F, Nanvuma A, Ocan M, Kafufu B, Mugalula F, Ssewanyana I, Castelnuovo B, Nabatanzi R, Bagaya BS.   +9 more
europepmc   +1 more source

The regulatory effects and applications of TIGIT/CD155 on the tumor microenvironment in HCC

VIEW, EarlyView.
Background The interaction between TIGIT and CD155 compromises immune cell efficacy in tumor targeting, potentially driving hepatocellular carcinoma (HCC) progression through diverse molecular pathways. What Was Done This study investigates the interplay between CD155 and TIGIT in regulating CD8+ T cell function and elucidates its implications in HCC ...
Wenting Li, Yukun Li, Yao Li, Mingqi Yang, Haichuan Peng, Hongwei Sun, Ping Jiang, Yizhun Zhu, Qiang Chen, Xiaobing Duan, Wei Zhao   +10 more
wiley   +1 more source

Evaluation of hepatitis A virus recombinant proteins for detecting anti-HAV IgM and IgG antibodies. [PDF]

Microbiol Spectr
Hunderkar S, Ganorkar N, Walimbe A, Lole K.   +3 more
europepmc   +1 more source

Epidemiological-clinical correlates of hepatitis B antigen subtypes.

, 1974
Gary R. Zuckerman, Edward Hacker, Richard D. Aach   +2 more
openalex  

Implications of Tobacco Use on Pathogen‐Driven Diseases: A Public Health and Policy Perspective

World Medical &Health Policy, EarlyView.
ABSTRACT The tobacco epidemic remains one of the most significant global public health challenges, responsible for over 8 million deaths annually, with a substantial portion occurring among non‐smokers exposed to second‐hand smoke. While cigarette smoking remains the most prevalent form of tobacco use worldwide, the rise of electronic nicotine delivery
Nadine Kabbani, James L. Olds
wiley   +1 more source

A Multivalent mRNA Therapeutic Vaccine Exhibits Breakthroughs in Immune Tolerance and Virological Suppression of HBV by Stably Presenting the Pre-S Antigen on the Cell Membrane. [PDF]

Pharmaceutics
Liu S, Wang J, Li Y, Wang M, Du P, Zhang Z, Li W, Sun R, Fan M, Yang M, Yin H.   +10 more
europepmc   +1 more source

Dynamic changes of serum cytokines and their prognostic values in patients with hepatocellular carcinoma treated by thermal ablation

Surgical Practice, EarlyView.
Abstract Background Thermal ablation is effective for early‐stage hepatocellular carcinoma (HCC). It can induce a host immune response through dynamic changes in serum cytokines. It is unknown whether this host immune response correlates with tumour recurrence.
Kelvin K. C. Ng, Charing C. N. Chong, Chun‐Kwok Wong, Nathalie Wong   +3 more
wiley   +1 more source