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Mathematical Analysis of Autonomous and Nonautonomous Hepatitis B Virus Transmission Models [PDF]

, 2023
This study presents an improved mathematical model for Hepatitis B Virus (HBV) transmission dynamics by investigating autonomous and nonautonomous cases. The novel model incorporates the effects of medical treatment, allowing for a more comprehensive understanding of HBV transmission and potential control measures.
arxiv   +1 more source

Modulation of the CD8+-T-cell response by CD4+ CD25+ regulatory T cells in patients with Hepatitis B virus infection [PDF]

, 2005
CD4+ CD25+ regulatory T cells have been shown to maintain peripheral tolerance against self and foreign antigens. In this study we analyzed the effect of circulating CD4+ CD25+ T cells on CD8+-T-cell responses of patients with chronic and resolved ...
Bertoletti, A., Franzese, O., Gehring, A.J., Gotto, J., Kennedy, P.T.F., Maini, M.K., Williams, R.   +6 more
core   +2 more sources

Detection of hepatitis B surface antigen, hepatitis B core antigen, and hepatitis B virus DNA in parotid tissues [PDF]

International Journal of Infectious Diseases, 2009
To examine the presence of hepatitis B surface antigen (HBsAg), hepatitis B core antigen (HBcAg), and hepatitis B virus (HBV) DNA in parotid tissues from patients with positive serum HBV markers.HBsAg and HBcAg were examined in parotid biopsy tissues from patients with suspected parotid tumor and positive serum HBV markers by immunocytochemistry, and ...
Fuqiang Liu, Shi Wu Wen, Xue-Gong Fan, Tom Wong, J. Wu, Nengzhi Chen, Lizhang Chen, Jian-Ming Gao   +7 more
openaire   +3 more sources

New virologic tools for management of chronic hepatitis B and C.: New Virological Tools [PDF]

, 2012
International audienceMolecular biology techniques are routinely used to diagnose and monitor treatment of patients with chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. These tools can detect and quantify viral genomes and analyze
Chevaliez, Stéphane, Pawlotsky, Jean-Michel, Rodriguez, Christophe   +2 more
core   +2 more sources

Baseline quantitative HBcAb strongly predicts undetectable HBV DNA and RNA in chronic hepatitis B patients treated with entecavir for 10 years

Scientific Reports, 2021
The predictive effect of quantitative anti-hepatitis B core on double-negative HBV DNA and RNA remains unstudied. We observed dynamic changes in this measure in chronic hepatitis B patients receiving entecavir for 10 years, evaluating its predictive ...
Xi Zhang, Xiaocui An, Lei Shi, Xueliang Yang, Yunru Chen, Xiaojing Liu, Jianzhou Li, Feng Ye, Shumei Lin   +8 more
doaj   +1 more source

Dynamical analysis of a generalized hepatitis B epidemic model and its dynamically consistent discrete model [PDF]

arXiv, 2021
The aim of this work is to study qualitative dynamical properties of a generalized hepatitis B epidemic model and its dynamically consistent discrete model.
arxiv  

Changes in the Hepatitis B Surface Antigen Level According to the HBeAg Status and Drug Used in Long-term Nucleos(t)ide Analog-treated Chronic Hepatitis B Patients

The Korean Journal of Gastroenterology, 2021
Background/Aims: The HBsAg levels have been used to monitor the chronic hepatitis B (CHB) treatment response to antiviral therapy. On the other hand, it is unclear if the HBsAg quantification levels at each treatment point differ according to the HBeAg ...
Jong Hwa Na, Jeong Han Kim, Won Hyeok Choe, So Young Kwon, Byung Chul Yoo   +4 more
doaj   +1 more source

The effects of symmetry on the dynamics of antigenic variation [PDF]

J. Math. Biol. 66, 115-137 (2013), 2012
In the studies of dynamics of pathogens and their interactions with a host immune system, an important role is played by the structure of antigenic variants associated with a pathogen. Using the example of a model of antigenic variation in malaria, we show how many of the observed dynamical regimes can be explained in terms of the symmetry of ...
arxiv   +1 more source

Apoptotic epitope-specific CD8+ T cells and interferon signaling intersect in chronic hepatitis C virus infection [PDF]

, 2015
CD8(+) T cells specific to caspase-cleaved antigens derived from apoptotic T cells represent a principal player in chronic immune activation (CIA). Here, we found that both apoptotic epitope (AE)-specific and hepatitis C virus (HCV)-specific CD8(+) T ...
Accapezzato, Daniele, Barnaba, Vincenzo, Calvo, Ludovica, Cavallari, EUGENIO NELSON, Citro, Alessandra, Coccia, Eliana M, D'Ettorre, Gabriella, DE MARZIO, Paolo, DI FILIPPO, Simona, Grazi, Gian Luca, Labbadia, Giancarlo, Martini, Helene, Martire, Carmela, Piconese, Silvia, Rizzo, Fabiana, Sette, Alessandro, Severa, Martina, Sidney, John, Vullo, Vincenzo   +18 more
core   +1 more source

Current diagnosis of occult or cryptic hepatitis B [PDF]

Einstein (São Paulo), 2005
The present article presents a kind of hepatitis B in patients whodo not have the surface antigen (HbsAg) detectable in sera. It hasbeen described in different parts of the world and is known todayas “occult or criptic hepatitis B” and its importance has
João Renato Rebello Pinho
doaj