Results 151 to 160 of about 54,525 (278)

Real‐World Impact of a Simplified ‘Test and Treat’ Strategy for In‐Hospital HCV Micro‐Elimination

Journal of Viral Hepatitis, Volume 33, Issue 3, March 2026.
ABSTRACT Hepatitis C virus (HCV) micro‐elimination faces challenges from fragmented care pathways, particularly in high‐prevalence regions with complex genotypes and socioeconomic barriers. This study evaluated a simplified ‘Test and Treat’ (TNT) strategy to enhance in‐hospital HCV micro‐elimination by reducing delays and improving linkage to care ...
Chunfang You, Yuting Diao, Juan Tang, Jing Tang, Wei Deng, Chunqi Zheng, Dongxia Liao, Dan Song, Jie Wang, Yangyang Pu   +9 more
wiley   +1 more source

Detection of anti-hepatitis C virus antibodies by ELISA using synthetic peptides [PDF]

, 1993
A novel ELISA assay for the detection of anti-hepatitis C virus antibodies in the sera of infected individuals is described. This assay is based on a mixture of three 15-amino acid synthetic peptides encompassing regions of core and NS4 proteins of ...
Berasain, C. (Carmen), Borras-Cuesta, F. (Francisco), Civeira, M.P. (María Pilar), Garcia-Granero, M. (Marta), Prieto, J. (Jesús), Riezu-Boj, J.I. (José Ignacio)   +5 more
core  

Novel Long‐Read Sequencing Method for Characterisation of Hepatitis B Transcripts Show High Expression of Chimeric HBV/Human RNA

Liver International, Volume 46, Issue 3, March 2026.
ABSTRACT Background Hepatitis B virus (HBV) genomes integrated into human DNA significantly contribute to surface antigen (HBsAg) production and may drive hepatocellular carcinoma (HCC). Long‐read sequencing methods like Nanopore offer advantages over short‐read next‐generation sequencing (NGS) by providing continuous reads of whole transcripts, but ...
Joakim Bedner Stenbäck, Johan Ringlander, Maria Andersson, Jakob Holm Dalsgaard Thomsen, Sanna Abrahamsson, Gustaf E. Rydell, Magnus Lindh   +6 more
wiley   +1 more source

Indeterminate Phase/Grey Zone of Chronic Hepatitis B: Clinical Features, Outcomes and Molecular Insights

Liver International, Volume 46, Issue 3, March 2026.
ABSTRACT Chronic hepatitis B virus (HBV) infection remains a global public health challenge, with a high risk of complications such as cirrhosis, hepatocellular carcinoma (HCC) and death. As outlined in current international society guidelines, antiviral therapies are aimed at preventing progression of liver disease to life‐threatening complications ...
Maria Stella Franzè, Teresa Pollicino, Jean‐Michel Pawlotsky, Vincent Leroy, Giovanni Raimondo, Giuliana Amaddeo   +5 more
wiley   +1 more source

Central blood volume in cirrhosis [PDF]

, 1993
Bendtsen, Flemming, Gerbes, Alexander L., Henriksen, Jens H.   +2 more
core   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, Volume 13, Issue 7, 3 February 2026.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Emerging studies indicate that microbes are present in tumor cells and immune cells. Intratumoral microbiota (ITM) constitute an important component of the tumor immune microenvironment (TIME) and have an important impact on tumor progression and treatment. Objective Through the general elaboration of ITM represented by bacteria and
Fengxue Li, Lili Qiao, Xinquan Liang, Yingying Zhang, Ning Liang, Jian Xie, Guodong Deng, Yuying Hao, Pingping Hu, Xue Wu, Fangjie Ding, Can Feng, Yiming Mu, Jiandong Zhang   +13 more
wiley   +1 more source

Disseminated Invasive Aspergillosis in a Young Patient With Chronic Alcohol Use and Seemingly Preserved Immunocompetence: A Case Report

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Invasive aspergillosis, though typically seen in immunocompromised patients, can also affect immunocompetent individuals and mimic pulmonary malignancy. This case highlights the importance of considering fungal infections in the differential diagnosis of chronic respiratory symptoms, particularly in patients with risk factors such as heavy ...
Kumail Khandwala, Hiba Sawliha Syed, Shayan Sirat Maheen Anwar, Sehar Suleman, Khabab Abbasher Hussien Mohamed Ahmed   +4 more
wiley   +1 more source

Comprehensive tumour‐immune profiling reveals TREM2+ tumour‐associated macrophages facilitating lymph node metastasis in head and neck squamous cell carcinoma

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
(1) TREM2+ TAMs promote CD8+ T cell exhaustion by upregulating BHLHE40 through the SPP1–CD44 axis, contributing to a suppressive tumour immune microenvironment in HNSCC. (2) CD8+ Tex induced by TREM2+ TAMs facilitates immune escape and promotes tumour cell metastasis via the lymphangion.
Zhuokai Wu, Chixing Cheng, Zhaoxin Li, Minyi Ren, Hongxi Cao, Weijie Huang, Jun Wang, Lixian Wu, Tingyi Lee, Sien Zhang, Hanhao Zheng, Yixi Wang   +11 more
wiley   +1 more source

Genetic variants underlying precancerous conditions of hepatocellular carcinoma

International Journal of Cancer, Volume 158, Issue 3, Page 488-502, 1 February 2026.
Abstract Hepatocellular carcinoma (HCC) is the most common form of liver cancer, accounting for 80% of cases worldwide. While chronic hepatitis B and C infections remain primary risk factors, emerging evidence highlights the increasing contributions of metabolic dysfunction‐associated steatotic liver disease (MASLD) and alcohol‐associated liver disease
Jonathan Jaime G. Guerrero, Paolo C. Encarnacion, Mark Angelo S. del Rosario, Matthew Aldren S. Ora, Jiayan Zhou, Kin Israel Notarte, Wan‐Chun Li, Ching‐Wen Chang   +7 more
wiley   +1 more source