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Hepatitis B surface antigen in late hepatitis B infection

Journal of Medical Virology, 2014
Hepatitis B surface antigen (HBsAg) levels are used to evaluate and monitor clinical phases of chronic hepatitis B infection but their clinical significance is unclear in the late complications, cirrhosis of the liver and hepatocellular carcinoma. This study aimed to evaluate HBsAg levels across the whole natural history of hepatitis B virus infection,
Jing Dong   +7 more
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Serum Hepatitis B Surface Antigen Levels Predict Surface Antigen Loss in Hepatitis B e Antigen Seroconverters

Gastroenterology, 2011
Loss of hepatitis B surface antigen (HBsAg) usually indicates that hepatitis B virus (HBV) infection has been cured. However, little is known about factors predicting HBsAg loss in patients who spontaneously clear hepatitis B e antigen (HBeAg).We studied 390 Taiwanese HBeAg-positive patients with chronic hepatitis who had spontaneously cleared HBeAg ...
Chia-Chi Wang   +7 more
openaire   +3 more sources

Comparison of two immunoassays for quantification of hepatitis B surface antigen in Chinese patients with concomitant hepatitis B surface antigen and hepatitis B surface antibodies

Archives of Virology, 2014
Two commercial quantitative immunoassay platforms are currently available for the detection of hepatitis B surface antigen (HBsAg) within a wide range of concentrations: the Architect HBsAg assay and the Elecsys HBsAg II. However, there are limited data concerning their performance in patients who are positive for both HBsAg and anti-HBs antibodies. In
Xinyu Wang   +4 more
openaire   +3 more sources

Hepatitis B Surface Antigen Seroclearance: Relationship to Hepatitis B e-Antigen Seroclearance and Hepatitis B e-Antigen-Negative Hepatitis

American Journal of Gastroenterology, 2014
The objective of this study was to determine factors associated with hepatitis B surface antigen (HBsAg) seroclearance after hepatitis B e-antigen (HBeAg) seroclearance.This is a cohort study of HBeAg-positive patients with HBeAg seroclearance. Factors associated with subsequent HBsAg seroclearance were examined.A total of 775 patients were included ...
Fung, JYY   +5 more
openaire   +5 more sources

Antibodies to Hepatitis B Surface Antigen

Annals of Internal Medicine, 1985
Excerpt To the editor: The article by Kessler and colleagues (1) is of general interest because it shows, once again, that antibodies to hepatitis B surface antigen (anti-HBs), at least as they are...
openaire   +3 more sources

Thyroxine Binding by Hepatitis B Surface Antigen

Journal of Infectious Diseases, 1975
Thyroxine and triiodothyronine binding sites are present on the 20-nm spherical particles associated with hepatitis B surface antigen (HBsAg). Thyroxine-treated HBsAg has a buoyant density of 1.26 g/cm-3 in CsCl and appears under the electron microscope as a hexagonal particle with a center-to-vertex distance of 10 nm.
A. R. Neurath   +4 more
openaire   +3 more sources

Hepatitis B surface antigen in spinal fluid

Medical and Pediatric Oncology, 1980
AbstractHepatitis B surface antigen (HBsAg) was detected in the cerebrospinal fluid (CSF) of five of nine leukemia patients with HBsAg‐positive sera. These five CSF samples were shown to be free of occult blood using a sensitive hemoglobin extraction technique.
Robert J. Spiegel   +3 more
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The Detection of Hepatitis B Surface Antigen by Radioimmunoassay

Pathology, 1975
A comparative study was performed to assess the sensitivity and specificity of counterimmunoelectrophoresis (CIEP) and radioimmunoassay (RIA) for the detection of hepatitis B surface antigen. The 8,823 sera examined included selected reference panels and sera collected from populations with low, moderate and high rates of chronic antigen carriage ...
Ian D. Gust, Noreen I. Lehmann
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Thermal Inactivation of Hepatitis B Surface Antigen

The Journal of Immunology, 1978
Abstract Thermal inactivation of hepatitis B surface antigen (HBs Ag) was investigated under various experimental conditions by means of a quantitative radioimmunoassay. No decrease of HBs Ag immunologic reactivity could be detected at -80°C, up to 24 months of storage, whereas at -20 and 4°C survival of serum HBs Ag after 6 months was ...
openaire   +3 more sources

The incidence of hepatitis B surface antigen in Nigeria

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1979
We have determined the incidence of hepatitis B surface antigen (HBsAg) in an urban (Enugu) and a rural (Okpatu) population groups in Nigeria. There were no statistically significant differences between the incidence in the two populations. Contrary to earlier reports we did not observe any significant age-related differences in the incidence rates ...
G.O. Okafor, G.O. Obi, W.O. Chukwudebelu
openaire   +3 more sources

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