Results 241 to 250 of about 97,023 (309)

Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications

MedComm, Volume 7, Issue 5, May 2026.
Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang, Xiaoqing Wang, Kai Luo, Tikam Chand Dakal, He Bai, Caiming Xu, Guixin Zhang   +6 more
wiley   +1 more source

Combination therapy with tobevibart and elebsiran potently reduces hepatitis B virus surface antigen levels in preclinical <i>in vivo</i> models. [PDF]

Antimicrob Agents Chemother
Noack J, Anglero-Rodriguez Y, Gall J, Zhou J, LeBlanc S, Liebow A, Bakardjiev A, Hebner CM, Purcell LA, Jadhav V, Corti D, Lempp FA.   +11 more
europepmc   +1 more source

HBV RNA at 6 months after nucleos(t)ide analogues treatment can predict antiviral efficacy in chronic hepatitis B patients. [PDF]

BMC Gastroenterol
Xie Y, Zhang X, Yang X, Zheng S, Zhang S, Zhang X, Kang H, Duan X, Cai W, Yin P, Ma X, Liu J, Lu F, Dai L, Feng B.   +14 more
europepmc   +1 more source

Distribution of domestic cat hepatitis B virus in cholangiocarcinoma and non-neoplastic liver tissue. [PDF]

J Vet Med Sci
Dosaka H, Kato NX, Taga K, Yamamoto S, Kondo K, Ringo RS, Kaneko Y, Hirai T, Saito A, Fuke N.   +9 more
europepmc   +1 more source

Generation of virus specific cytotoxic T cells in vitro [PDF]

, 1979
Greber, D., Koszinowski, Ulrich H., Neuschaefer-Rube, I.   +2 more
core  

A retrospective study of preoperative HBsAg levels predicting recurrence after curative resection in patients with HBV-associated hepatocellular carcinoma. [PDF]

Medicine (Baltimore)
Xu R, Su Q, Liao X, Zhu G, Su H, Han C, Wei Y, Zhou X, Ye X, Peng T.   +9 more
europepmc   +1 more source

Xenotransplantation: principles and practice [PDF]

, 1996
Fung, JJ, Starzl, TE, Todo, S, Valdivia, L   +3 more
core  

MAIT Cells in Liver Disease. [PDF]

Cells
Azad AI, Gutierrez F, Gores GJ.
europepmc   +1 more source

Tenofovir Alafenamide Fumarate Reduces Virological Replication in HBeAg-Negative Patients With Normal Alanine Aminotransferase: A 48-Week Randomised Controlled Trial. [PDF]

J Viral Hepat
Luo Q, Xu W, Zhang Y, Li X, Lai J, Li J, Zheng X, Deng H, Chen L, Zhu X, Xie C, Peng L.   +11 more
europepmc   +1 more source

Vaccine expression systems and maternal/neonatal factors: Impacts on hepatitis B immunization efficacy in preterm infants. [PDF]

Hum Vaccin Immunother
Shen L, Xie Y, Zhu Z, Wang J, Qian Y, Liu H, Yu Y, Tang W.   +7 more
europepmc   +1 more source