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Hepatitis B surface antigen monitoring and management of chronic hepatitis B

Journal of Viral Hepatitis, 2011
Summary.  Serum hepatitis B surface antigen (HBsAg) levels reflect intrahepatic hepatitis B virus (HBV) covalently closed circular DNA and may be a valuable addition to HBV DNA in the management of patients with chronic hepatitis B (CHB). Among HBeAg‐negative CHB patients with low HBV DNA levels, HBsAg quantification may help distinguish those with ...
Sonneveld, Milan   +2 more
openaire   +2 more sources

Hepatitis B caused by a hepatitis B surface antigen escape mutant

Journal of Gastroenterology, 2008
Amino acid substitutions within the S gene involving the major antigenic a determinant of the hepatitis B virus (HBV) surface antigen (HBsAg) have been detected in cases of failure of immunization against the virus. Our report showed development of clinical hepatitis in presence of antibody to HBsAg in a healthy individual.
Eiji, Kajiwara   +6 more
openaire   +2 more sources

Antibodies. to Hepatitis B Core Antigen in Hepatitis B Surface Antigen-Positive and -Negative Chronic Hepatitis

Journal of Infectious Diseases, 1977
Antibody to hepatitis B core antigen (anti-HBc) is a sensitive indicator of hepatitis B virus (HBV) infection. However, anti-HBc has been found in only a few patients with chronic hepatitis. Therefore, we tested for anti-HBc in 124 sera from 67 patients with histologically proven chronic hepatitis by the indirect fluorescent antibody technique.
M A, Gerber   +3 more
openaire   +2 more sources

Comparison of two immunoassays for quantification of hepatitis B surface antigen in Chinese patients with concomitant hepatitis B surface antigen and hepatitis B surface antibodies

Archives of Virology, 2014
Two commercial quantitative immunoassay platforms are currently available for the detection of hepatitis B surface antigen (HBsAg) within a wide range of concentrations: the Architect HBsAg assay and the Elecsys HBsAg II. However, there are limited data concerning their performance in patients who are positive for both HBsAg and anti-HBs antibodies. In
Weiwei, Liu   +4 more
openaire   +2 more sources

Quantification of hepatitis B surface antigen can help predict spontaneous hepatitis B surface antigen seroclearance

European Journal of Gastroenterology & Hepatology, 2012
The clinical outcomes of hepatitis B virus (HBV) carriers are favorable following hepatitis B surface antigen (HBsAg) seroclearance. The aim of this study was to investigate the clinical course of spontaneous HBsAg seroclearance and the factors predicting it.A total of 423 patients who tested positive for HBsAg and were referred to Chiba University ...
Makoto, Arai   +5 more
openaire   +2 more sources

Antigenicity of the Major Polypeptides of Hepatitis B Surface Antigen (HBsAg)

The Journal of Immunology, 1978
Abstract The major polypeptides (P-1, P-2, and P-6) of HBsAg were isolated from purified preparations of 22-nm HBsAg particles, iodinated, and analyzed by double-antibody radioimmunoprecipitation assays for the presence of hepatitis B virus (HBV)-specific antigens.
J W, Shih, P L, Tan, J L, Gerin
openaire   +2 more sources

Origin of salivary hepatitis B surface antigen

European Journal of Oral Sciences, 1980
Abstract –Low titers of hepatitis B surface antigen (HBsAg) is often found in mixed saliva of antigenemic individuals. In the present study the occurrence of antigen in saliva was correlated to the content of albumin, which is not synthesized by the salivary glands, but represents a leakage into the oral cavity due to hemorrhage, exudation or ...
openaire   +2 more sources

Surveillance for hepatitis B surface antigen mutants

Journal of Medical Virology, 2006
Hepatitis B viral (HBV) mutants can emerge in patients as a result of selection pressure from treatment options. Some mutations that occur in the immunodominant "a" determinant of hepatitis B surface antigen (HBsAg) can present as false negative results in HBsAg immunoassays.
openaire   +2 more sources

Dual-label vertical flow-based electrochemical immunosensor for rapid and simultaneous detection of hepatitis B surface and e virus antigens

Sensors and Actuators B: Chemical, 2023
Sakda Jampasa   +2 more
exaly  

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