Results 1 to 10 of about 14,427,656 (303)

Evaluation of fully automated chemiluminescent enzyme immunoassays for hepatitis B core-related antigen components, phosphorylated and non-phosphorylated hepatitis B core antigens: clinical significance and dynamics during hepatitis B e antigen seroconversion [PDF]

Journal of Clinical Microbiology
To assess the performance and clinical relevance of three assays—hepatitis B core-related antigen (HBcrAg), hepatitis B core antigen (HBcAg), and phosphorylated HBcAg (pHBcAg)—in quantifying HBcrAg, a critical biomarker of hepatitis B virus (HBV ...
Takanori Suzuki, Chiharu Ohue, Osamu Arai, Yuka Inose, Katsuya Nagaoka, Shintaro Ogawa, Takako Inoue, Kentaro Matsuura, Katsumi Aoyagi, Shintaro Yagi, Yasuhito Tanaka   +10 more
doaj   +2 more sources

Expression of Hepatocyte Hepatitis B Core Antigen and Hepatitis B Surface Antigen as a Marker in the Management of Chronic Hepatitis B Patients

Gut and Liver, 2017
Background/AimsWe aimed to clarify the association of hepatitis B surface antigen (HBsAg)/hepatitis B core antigen (HBcAg) with the disease status and treatment response in patients with chronic hepatitis B (CHB).Methods : We investigated 171 biopsy ...
Sun Young Yim, Tae Hyung Kim, Suh Sang Jun, Eun Sun Kim, Bora Keum, Yeon Seok Seo, Hyung Joon Yim, Yoon Tae Jeen, Hoon Jai Chun, Hong Sik Lee, Soon Ho Um, Chang Duck Kim, Nam Hee Won, Ho Sang Ryu   +13 more
doaj   +4 more sources

Characterization of Hepatitis B Precore/Core-Related Antigens

Journal of Virology, 2021
Chronic hepatitis B virus (HBV) infection afflicts approximately 257 million people, who are at high risk of progressing to chronic liver diseases, including fibrosis, cirrhosis, and hepatocellular carcinoma. Current therapies rarely achieve cure of HBV infection due to the persistence of the HBV episome, the covalently closed circular DNA (cccDNA), in
Renae Walsh, Jianming Hu, Xupeng Hong
exaly   +4 more sources

Community-Based Screening for Hepatitis B and C Infectivity Using Two Quantitative Antigens to Identify Endemic Townships

Viruses, 2022
Screening and linkage to care are essential to achieve viral hepatitis elimination before 2030. The accurate identification of endemic areas is important for controlling diseases with geographic aggregation.
Wei-Cheng Huang, Yu-Chen Lin, Po-Ju Chen, Nien-Tzu Hsu, Chia-Ling Tu, Te-Sheng Chang, Chao-Hung Hung, Kwong-Ming Kee, Wen-Hua Chao, Sheng-Nan Lu   +9 more
doaj   +3 more sources

Protein Priming Followed by a Replication-Competent VSV-GP Vector Boost Induces Sustained Immune Control in Therapeutic Hepatitis B Vaccination [PDF]

Vaccines
Background/Objectives: Eliciting robust immune responses against the hepatitis B virus (HBV) through therapeutic vaccination holds promise for curing chronic hepatitis B.
Jinpeng Su, Anna D. Kosinska, Susanne Miko, Edanur Ates Öz, Dorothee von Laer, Janine Kimpel, Ulrike Protzer   +6 more
doaj   +2 more sources

Correction for Suzuki et al., “Evaluation of fully automated chemiluminescent enzyme immunoassays for hepatitis B core-related antigen components, phosphorylated and non-phosphorylated hepatitis B core antigens: clinical significance and dynamics during hepatitis B e antigen seroconversion” [PDF]

Journal of Clinical Microbiology
Takanori Suzuki, Chiharu Ohue, Osamu Arai, Yuka Inose, Katsuya Nagaoka, Shintaro Ogawa, Takako Inoue, Kentaro Matsuura, Katsumi Aoyagi, Shintaro Yagi, Yasuhito Tanaka   +10 more
doaj   +2 more sources

Hepatitis B Core-Related Antigen and New Therapies for Hepatitis B [PDF]

Microorganisms, 2021
The hepatitis B core-related antigen (HBcrAg) is an unprecedented novel HBV biomarker that plays an essential role in reflecting covalently closed circular DNA (cccDNA) in chronic hepatitis B (CHB) because its levels correlate with intrahepatic cccDNA and serum HBV DNA.
Takehisa Watanabe, Takako Inoue, Yasuhito Tanaka   +2 more
openaire   +3 more sources

Nuclear Expression of Hepatitis B Virus X Protein Is Associated with Recurrence of Early-Stage Hepatocellular Carcinomas: Role of Viral Protein in Tumor Recurrence [PDF]

Journal of Pathology and Translational Medicine, 2016
Background: Hepatitis B virus (HBV) plays well-known roles in tumorigenesis of hepatocellular carcinoma (HCC) in infected patients. However, HBV-associated protein status in tumor tissues and the relevance to tumor behavior has not been reported.
Jing Jin, Hae Yoen Jung, Kyu Ho Lee, Nam-Joon Yi, Kyung-Suk Suh, Ja-June Jang, Kyoung-Bun Lee   +6 more
doaj   +1 more source

The Relationship of Hepatits B Core Antibody Positivity with Demographic and Laboratory Parameters in Hemodialysis Patients

Haseki Tıp Bülteni, 2021
Aim:The presence of hepatitis B core antibody (HBcAb) is an indication of exposure to hepatitis B virus infection. We aimed to investigate the rates of positive HBcAb and its’ association with demographical and laboratory parameters among patients ...
Ilter Bozaci, Selma Tosun
doaj   +1 more source

Baseline quantitative HBcAb strongly predicts undetectable HBV DNA and RNA in chronic hepatitis B patients treated with entecavir for 10 years

Scientific Reports, 2021
The predictive effect of quantitative anti-hepatitis B core on double-negative HBV DNA and RNA remains unstudied. We observed dynamic changes in this measure in chronic hepatitis B patients receiving entecavir for 10 years, evaluating its predictive ...
Xi Zhang, Xiaocui An, Lei Shi, Xueliang Yang, Yunru Chen, Xiaojing Liu, Jianzhou Li, Feng Ye, Shumei Lin   +8 more
doaj   +1 more source