Results 11 to 20 of about 14,427,656 (303)
Vaccines, 2022 Nasvac (HeberNasvac®) is a novel therapeutic vaccine for chronic hepatitis B (CHB). This product is a formulation of the core (HBcAg) and surface (HBsAg) antigens of the hepatitis B virus (HBV), administered by nasal and subcutaneous routes, in a ...
Julio Cesar Aguilar +2 more
doaj +1 more source
Programmable Nanobody-Targeting Chimeras Enable Intracellular Viral Protein Degradation. [PDF]
Adv Sci (Weinh)Nab‐TAC enables targeted degradation of HBV surface antigen (HBsAg) in vivo. By fusing nanobody‐based recognition domains with programmable proteasome‐recruiting degradation signals, Nab‐TAC reduces HBsAg levels in a hydrodynamic HBV mouse model. ABSTRACT Chronic hepatitis B virus (HBV) infection remains a major global health challenge, largely because
Pan MY +11 more
europepmc +2 more sources
The Role of Hepatitis B Core-Related Antigen [PDF]
Genes, 2019 Hepatitis B virus (HBV) cannot be completely eliminated from infected hepatocytes due to the existence of intrahepatic covalently closed circular DNA (cccDNA). Serological biomarkers reflect intrahepatic viral replicative activity as non-invasive alternatives to liver biopsy.
Inoue, Takako, Tanaka, Yasuhito
openaire +2 more sources
BMC Research Notes, 2022 Objective Use of dried blood spots (DBS) for detection of hepatitis B virus (HBV) markers of infection has the potential to facilitate diagnosis of HBV infection especially in resource-limited countries.
Minami Kikuchi +5 more
doaj +1 more source
VelcroVax: a “Bolt-On” Vaccine Platform for Glycoprotein Display
mSphere, 2023 Having varied approaches to the design and manufacture of vaccines is critical in being able to respond to worldwide needs and newly emerging pathogens.
Natalie J. Kingston +19 more
doaj +1 more source
Predominance of HBV Genotype B and HDV Genotype 1 in Vietnamese Patients with Chronic Hepatitis
Viruses, 2021 Hepatitis delta virus (HDV) coinfection will additionally aggravate the hepatitis B virus (HBV) burden in the coming decades, with an increase in HBV-related liver diseases.
Nghiem Xuan Hoan +14 more
doaj +1 more source
Modulation of the CD8+-T-cell response by CD4+ CD25+ regulatory T cells in patients with Hepatitis B virus infection [PDF]
, 2005 CD4+ CD25+ regulatory T cells have been shown to maintain peripheral tolerance against self and foreign antigens. In this study we analyzed the effect of circulating CD4+ CD25+ T cells on CD8+-T-cell responses of patients with chronic and resolved ...
Gotto, J +19 more
core +1 more source
Non-responsiveness to hepatitis-B vaccination: revaccination and immunogenetic typing [PDF]
, 1988 Krämer A, Herth D, von Keyserlingk H, et al. Non-responsiveness to hepatitis-B vaccination: revaccination and immunogenetic typing. Klinische Wochenschrift.
Sommer, D. +7 more
core +1 more source
Monoclonal Antibodies Specific for Hepatitis B e Antigen and Hepatitis B Core Antigen
Hybridoma, 2011 Despite effective vaccination programs in many countries, HBV infection is still a serious health problem throughout the world; more than 2 billion people have been infected with Hepatitis B virus (HBV). The serologic markers are crucial indicators in clinical diagnosis of HBV infection. The persistent presence of anti-HBc is associated with chronicity,
Sogut, Ibrahim +3 more
openaire +4 more sources
Detection of hepatitis B surface antigen, hepatitis B core antigen, and hepatitis B virus DNA in parotid tissues [PDF]
International Journal of Infectious Diseases, 2009 To examine the presence of hepatitis B surface antigen (HBsAg), hepatitis B core antigen (HBcAg), and hepatitis B virus (HBV) DNA in parotid tissues from patients with positive serum HBV markers.HBsAg and HBcAg were examined in parotid biopsy tissues from patients with suspected parotid tumor and positive serum HBV markers by immunocytochemistry, and ...
Chen, Lizhang +7 more
openaire +2 more sources