Results 11 to 20 of about 15,346,844 (86)

Modulation of the CD8+-T-cell response by CD4+ CD25+ regulatory T cells in patients with Hepatitis B virus infection [PDF]

, 2005
CD4+ CD25+ regulatory T cells have been shown to maintain peripheral tolerance against self and foreign antigens. In this study we analyzed the effect of circulating CD4+ CD25+ T cells on CD8+-T-cell responses of patients with chronic and resolved ...
Gotto, J, Ornella Franzese, Antonio Bertoletti, Maini, Mk, Franzese, O., Williams, R., Adam J. Gehring, Gehring, A.J., Roger Williams, Gehring, Aj, Gotto, J., Bertoletti, A., Kennedy, P.T.F., Williams, R, Maini, M.K., Patrick T. F. Kennedy, Kennedy, Ptf, Jim Gotto, Mala K. Maini, FRANZESE, ORNELLA   +19 more
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Characterization and Application of Precore/Core‐Related Antigens in Animal Models of Hepatitis B Virus Infection

, 2021
The hepatitis B core-related antigen (HBcrAg), a composite antigen of precore/core gene including classical hepatitis B core antigen (HBc) and e antigen (HBeAg), and additionally, the precore-related antigen PreC, retaining the N-terminal signal peptide,
Luckenbaugh, Laurie, Stefan F. Wieland, Perlman, David, David Perlman, Hu, Jianming, Menne, Stephan, Jianming Hu, Laurie Luckenbaugh, Peter A. Revill, Stephan Menne, Hong, Xupeng, Revill, Peter A., Wieland, Stefan F., Xupeng Hong   +13 more
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Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus infection [PDF]

, 2002
Deletion, anergy, and a spectrum of functional impairments can affect virus-specific CD8 cells in chronic viral infections. Here we characterize a low frequency population of CD8 cells present in chronic hepatitis B virus (HBV) infection which survive in
Antonio Bertoletti, Brown, D., Dusheiko, G., Geoff Dusheiko, Williams, R., George J.M. Webster, Webster, G.J.M., David Brown, Mala K. Maini, Stephanie Reignat, King, A., Suranjith L. Seneviratne, Roger Williams, Bertoletti, A., Reignat, S., Maini, M.K., Graham S. Ogg, Abigail King, Ogg, G.S., Seneviratne, S.L.   +19 more
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Non-responsiveness to hepatitis-B vaccination: revaccination and immunogenetic typing [PDF]

, 1988
Krämer A, Herth D, von Keyserlingk H, et al. Non-responsiveness to hepatitis-B vaccination: revaccination and immunogenetic typing. Klinische Wochenschrift.
Sommer, D., Ludwig, W. D., Hampl, Hartmut, Riecken, Ernst-Otto, Krämer, Alexander ; https://orcid.org/, Hahn, E. G., von Keyserlingk, H., Herth, D., W. -D. Ludwig, E. O. Riecken, D. Sommer, H. Hampl, A. Krämer, H. -J. Keyserlingk, E. G. Hahn, D. Herth   +15 more
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Immunological aspects of persistent hepatitis B in children [PDF]

, 2001
We studied the immunological status of 203 children having persistence Hepatitis B (positive HBsAg) ranging in age from 6 to 14 years in Semarang Municipality.
Notoatmojo, Harsoyo
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Viral adaptation to host immune responses occurs in chronic hepatitis B virus (HBV) infection, and adaptation is greatest in HBV e antigen-negative disease [PDF]

, 2012
Hepatitis B virus (HBV)-specific T-cell responses are important in the natural history of HBV infection. The number of known HBV-specific T-cell epitopes is limited, and it is not clear whether viral evolution occurs in chronic HBV infection. We aimed to
Chopra, A., Gordon, A, Scott Bowden, Pfafferott, K, Desmond, P.V., Ian R. James, Revill, P.A., Chopra, A, Mallal, SA, Silvana Gaudieri, Anna Ayres, Lewin, S.R., Thompson, AJ, Desmond, C.P., Jennifer Audsley, James, IR, Locarnini, SA, Stephen A. Locarnini, Sharon R. Lewin, James, I.R., Locarnini, S.A., Chivers, S., Christopher P. Desmond, Desmond, PV, Thompson, A.J., Stuart K. Roberts, Audsley, J, Revill, PA, Lau, GK, Gaudieri, S, Gaudieri, S., Audsley, J., Day, C, Caroline Day, Ayres, A, Day, C., Paul V. Desmond, Pfafferott, K., Gordon, A., Roberts, SK, Peter A. Revill, Alexander J. Thompson, Ayres, A., Desmond, CP, Sarah Chivers, Katja Pfafferott, Bowden, S., George K. Lau, Simon A. Mallal, Lewinb, SR, Lau, G.K., Roberts, S. K., Abha Chopra, Bowden, S, Mallal, S.A., Adam Gordon, Chivers, S   +56 more
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Evidence for hepatitis B and other virus infection in HBsAg-negative chronic active hepatitis.

, 1980
Antibody to the hepatitis B core antigen (anti-HBc) was detected in sera from 6 (19%) of 32 patients with HBsAg-negative chronic active hepatitis. In three cases with the highest anti-HBc titers, core antigen was detected in liver cell nuclei and in one ...
Williams R., Portmann B, VILLA, Erica, Eddleston AL, Jenkins P   +4 more
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Action Mechanisms and Scientific Rationale of Using Nasal Vaccine (HeberNasvac) for the Treatment of Chronic Hepatitis B

, 2022
Nasvac (HeberNasvac®) is a novel therapeutic vaccine for chronic hepatitis B (CHB). This product is a formulation of the core (HBcAg) and surface (HBsAg) antigens of the hepatitis B virus (HBV), administered by nasal and subcutaneous routes, in a ...
Aguiar, Jorge Agustin, Jorge Aguiar, Sheikh Akbar, Julio Aguilar, Aguilar, Julio Cesar, Akbar, Sheikh Mohammad Fazle   +5 more
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Peptides that inhibit the association of the surface and core antigens of hepatitis B virus

, 2001
This invention relates to isolation of high affinity binding phages carrying the fusion peptides which bind specifically to hepatitis B core antigen. A synthetic peptide derived from of the fusion peptides inhibits the association of hepatitis B surface ...
Seow, Heng Fong, Ho, Kok Lian, Yusoff, Khatijah, Tan, Wen Siang   +3 more
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Tracking the source of the hepatitis B virus-specific CD8 T cells during lamivudine treatment [PDF]

, 2003
Lamivudine treatment in chronic hepatitis B leads to the reconstitution of virus-specific T cells in the circulation, but it is not clear whether this is the preferential result of T cell efflux from the liver or lymph nodes.
Gotto, J, Williams, R, Webster, GJM, Dusheiko, GM, Bertoletti, A, Malacarne, F, Reignat, S, Behboudi, S, Burroughs, AK   +8 more
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