Results 31 to 40 of about 14,427,656 (303)

Immunological aspects of persistent hepatitis B in children [PDF]

open access: yes, 2001
We studied the immunological status of 203 children having persistence Hepatitis B (positive HBsAg) ranging in age from 6 to 14 years in Semarang Municipality.
Notoatmojo, Harsoyo
core   +1 more source

Hepatitis B testing practices at a tertiary care centre and their associated costs: A retrospective analysis.

open access: yesPLoS ONE, 2019
BackgroundHepatitis B is a viral infection requiring specific serologic testing to diagnose the stage of the disease. There are many tests which can be ordered in a variety of combinations.
Alexander Lawandi   +2 more
doaj   +1 more source

Does limited virucidal activity of biocides include duck hepatitis B virucidal action? [PDF]

open access: yes, 2012
BACKGROUND: There is agreement that the infectivity assay with the duck hepatitis B virus (DHBV) is a suitable surrogate test to validate disinfectants for hepatitis B virucidal activity.
Wutzler, Peter   +11 more
core   +2 more sources

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

open access: yesHepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog   +12 more
wiley   +1 more source

Hepatitis associated with hepatitis B virus in broilers

open access: yesJournal of Integrative Agriculture, 2016
Infection by hepatitis B virus (HBV) results in acute and chronic liver damages in humans. Liver products of broilers as a primary food consumed in our daily life have a close connection with public health. The prevalence of the virus in livers and serum
Yue ZHAO   +10 more
doaj   +1 more source

Serum hepatitis B core-related antigen as a surrogate marker of hepatitis B e antigen seroconversion in chronic hepatitis B

open access: yesWorld Journal of Gastroenterology, 2021
Quantitative hepatitis B core-related antigen (qHBcrAg) has a better correlation with intrahepatic hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) than HBV DNA or hepatitis B e antigen (HBeAg), but data are still lacking for its clinical application.The aim was to investigate serum qHBcrAg levels in patients with chronic hepatitis B and
Chi, Xiu-Mei   +7 more
openaire   +2 more sources

Inhibition of HBV Expression in HBV Transgenic Mice Using AAV-Delivered CRISPR-SaCas9

open access: yesFrontiers in Immunology, 2018
The chronic production of hepatitis B viral (HBV) antigens could cause inflammation and necrosis, leading to elevation of liver enzymes from necrotic hepatocytes, hepatitis, cirrhosis, hepatocellular carcinoma, and liver failure.
Hao Li   +14 more
doaj   +1 more source

HBV Vaccines: Advances and Development

open access: yesVaccines, 2023
Hepatitis B virus (HBV) infection is a global public health problem that is closely related to liver cirrhosis and hepatocellular carcinoma (HCC). The prevalence of acute and chronic HBV infection, liver cirrhosis, and HCC has significantly decreased as ...
Faisal Mahmood   +9 more
doaj   +1 more source

Role of B cells in antigen presentation of the hepatitis B core [PDF]

open access: yesProceedings of the National Academy of Sciences, 1997
The hepatitis B virus (HBV) nucleocapsid or core antigen (HBcAg) is extremely immunogenic during infection and after immunization. For example, during many chronic infections, HBcAg is the only antigen capable of eliciting an immune response, and nanogram amounts of HBcAg elicit antibody production in mice.
D R, Milich   +5 more
openaire   +2 more sources

A whole recombinant yeast-based therapeutic vaccine elicits HBV X, S and Core specific T cells in mice and activates human T cells recognizing epitopes linked to viral clearance.

open access: yesPLoS ONE, 2014
Chronic hepatitis B infection (CHB) is characterized by sub-optimal T cell responses to viral antigens. A therapeutic vaccine capable of restoring these immune responses could potentially improve HBsAg seroconversion rates in the setting of direct acting
Thomas H King   +18 more
doaj   +1 more source

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