Immune response to hepatitis B surface antigen [PDF]
A total of 69 persons were investigated for assessment of cell-mediated and humoral immunity to hepatitis B surface antigen (HBsAg). Three groups, each consisting of 20 normal persons, 20HBsAg carriers, and 20 convalescent hepatitis B patients, were studied for HBsAg, anti-HBs, and leukocyte migration inhibition with purified HBsAg. Sequential sampling
A B, Ibrahim, G N, Vyas, H A, Perkins
openaire +2 more sources
HBsAg-vectored DNA vaccines elicit concomitant protective responses to multiple CTL epitopes relevant in human disease. [PDF]
Vaccines capable of controlling neoplastic and infectious diseases which depend on the cellular immune response for their resolution, have proven difficult to develop.
Allan Gould +7 more
core +1 more source
Evolution of hepatitis B virus liver disease after hepatic replacement. Practical and theoretical considerations [PDF]
The morphologic evolution of hepatitis B virus (HBV) liver disease in 45 hepatic allograft recipients who were HBV surface-antigen positive (HBs-Ag+) at the time of liver replacement and who survived for more than 60 days was studied by routine ...
Demetris, AJ +8 more
core +1 more source
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang +9 more
wiley +1 more source
Predictive value of HBeAg titer dynamics for HBsAg clearance in pediatric chronic hepatitis B
IntroductionAchieving functional cure of chronic hepatitis B (CHB), characterized by the loss of HBV DNA and HBsAg, remains challenging in adults but demonstrates higher success rates in children.
Sukjin Hong +8 more
doaj +1 more source
Population, sexual and reproductive health, rights and sustainable development: forging a common agenda. [PDF]
This article suggests that sexual and reproductive health and rights activists seeking to influence the post-2015 international development paradigm must work with sustainable development advocates concerned with a range of issues, including climate ...
Campbell, D. M. +11 more
core +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Serosurveillance of vaccine preventable diseases and hepatitis C in healthcare workers from Lao PDR. [PDF]
BACKGROUND AND AIMS:Healthcare workers (HCW) have an increased risk of exposure to infectious diseases and are a potential source of infections for their patients.
Antony P Black +5 more
doaj +1 more source
HDV can constrain HBV genetic evolution in hbsag: Implications for the identification of innovative pharmacological targets [PDF]
Chronic HBV + HDV infection is associated with greater risk of liver fibrosis, earlier hepatic decompensation, and liver cirrhosis hepatocellular carcinoma compared to HBV mono-infection.
Andreoni, Massimo +34 more
core +2 more sources
Free‐Form Microfluidic Microneedle Array Patches
Microfluidic microneedle array patches (MAPs) integrate hollow microneedles with embedded microfluidic channels, fabricated using high‐resolution 3D printing, to enable controlled transdermal delivery of liquid, mixed, or reconstituted therapeutics.
Ian A. Coates +11 more
wiley +1 more source

