Results 41 to 50 of about 470,387 (242)

Using Enzyme-Linked Aptamer Assay to Detect Hepatitis B Surface Antigen in Comparison to Enzyme-Linked Immunosorbent Assay

مجله دانشکده پزشکی اصفهان, 2018
Background: Clinical diagnostic kits for detecting hepatitis B are based on antibodies, and have inefficient sensitivity, stability, and cost. Therefore, researches about aptamers and using them instead of antibodies may make these defects up.
Hamidreza Mianesaz, Hossein Khanahmad, Mina Mirian, Maryam Boshtam, Seyed Nezamoddin Hoseini   +4 more
doaj   +1 more source

Carbohydrate Composition of Hepatitis B Surface Antigen

Journal of General Virology, 1977
The content and composition of carbohydrate in hepatitis B surface antigen HBsAg) were clarified by gas chromatography. A value of 75-8 microgram carbohydrate per mg of protein was obtained. The main components were N-acetylglucosamine, mannose, galactose and sialic acid and the minor one was fucose. No N-acetyl-galactosamine was detected.
H. Shiraishi, Nakao Ishida, T. Kohama, R. Shirachi   +3 more
openaire   +3 more sources

Hepatitis B Surface Antigen Quantification across Different Phases of Chronic Hepatitis B Virus Infection Using an Immunoradiometric Assay

Gut and Liver, 2015
Background/AimsQuantification of hepatitis B surface antigen (HBsAg) is an emerging serologic test and may be useful for identifying treatment strategies for chronic hepatitis B (CHB).
doaj   +1 more source

Action Mechanisms and Scientific Rationale of Using Nasal Vaccine (HeberNasvac) for the Treatment of Chronic Hepatitis B

Vaccines, 2022
Nasvac (HeberNasvac®) is a novel therapeutic vaccine for chronic hepatitis B (CHB). This product is a formulation of the core (HBcAg) and surface (HBsAg) antigens of the hepatitis B virus (HBV), administered by nasal and subcutaneous routes, in a ...
Julio Cesar Aguilar, Jorge Agustin Aguiar, Sheikh Mohammad Fazle Akbar   +2 more
doaj   +1 more source

Molecular detection of hepatitis delta virus in blood donors with RT-PCR

Medical Laboratory Journal, 2015
Background and Objective: Hepatitis delta virus is an imperfect virus with RNA and its activity depends on the presence of hepatitis B virus. This virus can lead to acute and chronic diseases in the liver.
Malekpour, B., Tajbakhsh, E, Khamesipour, F, Rahimi, A   +3 more
doaj  

Randomised controlled trial: effect of metformin add-on therapy on functional cure in entecavir-treated patients with chronic hepatitis B

Annals of Hepatology, 2022
Introduction and Objectives: Hepatitis B surface antigen (HBsAg) clearance, indicating functional cure or resolved chronic hepatitis B (CHB), remains difficult to achieve via nucleos(t)ide analogue monotherapy.
Wei Zhang, Yuan-Yuan Li, Qing-Hua Shang, Lin Qi, Mi-Mi Sun, Gang Chen, Yong An, Jing-Xin Li, Wang-Ping Jia, Zhong-An Sun, Hui-Bin Xu, Qing-Mei Gao, Li Tang, Xiao-Wen Wang, Ji-Yuan Zhang, Yi-Ming Mu, Fu-Sheng Wang   +16 more
doaj  

A simple-to-use score system for predicting HBsAg clearance to peginterferon alfa-2b in nucleoside analogs-experienced chronic hepatitis B patients

Frontiers in Medicine, 2023
ObjectivePatients with chronic hepatitis B (CHB) often fail to achieve clearance of the hepatitis B surface antigen (HBsAg) with peginterferon treatment.
Kaimin Song, Dawu Zeng, Yijuan Zheng, Huatang Zhang, Zhangyan Weng, Yongjun Zhou, Zhijun Su, Xueping Yu   +7 more
doaj   +1 more source

Establishment of a yeast-based VLP platform for antigen presentation

Microbial Cell Factories, 2018
Background Chimeric virus-like particles (VLP) allow the display of foreign antigens on their surface and have proved valuable in the development of safe subunit vaccines or drug delivery.
David Wetzel, Theresa Rolf, Manfred Suckow, Andreas Kranz, Andreas Barbian, Jo-Anne Chan, Joachim Leitsch, Michael Weniger, Volker Jenzelewski, Betty Kouskousis, Catherine Palmer, James G. Beeson, Gerhard Schembecker, Juliane Merz, Michael Piontek   +14 more
doaj   +1 more source

Chemiluminescent Optical Fiber Immunosensor Combining Surface Modification and Signal Amplification for Ultrasensitive Determination of Hepatitis B Antigen

Sensors, 2020
Optical fiber based immunosensors are very attractive for biomarker detection. In order to improve the sensor response, we propose a promising strategy which combines porous-layer modification of the fiber surface and streptavidin-biotin-peroxidase nano ...
Xuexue Xu, Rongbin Nie, Jingwen Huang, Li Yang   +3 more
doaj   +1 more source

Atopological Model for Hepatitis B Surface Antigen

Intervirology, 1992
A model of hepatitis B surface antigen has been derived, based on extensive sequence analysis and biochemical data. The surface antigen sequences of the human, woodchuck, ground squirrel and duck hepadnaviruses were examined using hydrophobicity, hydrophobic moments, flexibility and secondary structure prediction.
Janet M. Thornton, C R Howard, H.J. Stirk   +2 more
openaire   +2 more sources