Increased neonatal vaccine dose or booster immunization prevents hepatitis B vaccine breakthrough infection in children from HBsAg and HBeAg positive mothers. [PDF]
Pan Y +8 more
europepmc +1 more source
ABSTRACT Objective To assess whether antivirals are associated with a reduced incidence of uveitis following COVID‐19. Methods We conducted a multi‐institutional, population‐based retrospective cohort study of adults (≥ 18 years) diagnosed with COVID‐19 between 2022 and 2024. Patients who received antiviral agents (Paxlovid, Molnupiravir, or Remdesivir)
Hou‐Ting Kuo +14 more
wiley +1 more source
Predicting optimal impact interventions in the post‐HPV vaccination world
Abstract Prophylactic vaccination is a powerful tool that changes exposure to infections and associated morbidity of preventable diseases. We discuss the impact of pneumococci and human papillomavirus (HPV) vaccination on the population biology of the two micro‐organisms and related public health effects.
Matti Lehtinen +7 more
wiley +1 more source
Assessing the psychometric properties of a modified vaccine hesitancy scale for measuring hepatitis B vaccine hesitancy among healthcare workers in Southern Ghana. [PDF]
Senoo-Dogbey VE +4 more
europepmc +1 more source
ABSTRACT The disease course of severe enterovirus (EV) infection with hepatic necrosis is usually fulminant and fatal. Coxsackievirus (CVB3) is the emerging and important serotype of newborn EV inducing hepatic necrosis. Calcium (Ca2+) regulates host immunity, type I interferon (IFN‐I), and viral infections.
Yi‐Ling Hsiao +3 more
wiley +1 more source
Hepatitis B vaccine coverage in health care students: a cross-sectional study in Vietnam. [PDF]
Vo LT +6 more
europepmc +1 more source
Abstract Objectives Patients with inflammatory bowel disease (IBD) are at increased risk of vaccine‐preventable diseases. However, vaccination coverage in this population is often suboptimal. This retrospective study assessed the vaccination status and vaccine serology of children diagnosed with IBD in a high‐income country with broad vaccine access ...
Clara Noble +4 more
wiley +1 more source
Heplisav-B vs Standard Hepatitis B Vaccine Booster for Health Care Workers. [PDF]
Williams AL, Newman RS.
europepmc +1 more source
Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications
Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang +6 more
wiley +1 more source
Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy
Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley +1 more source

