Results 211 to 220 of about 94,533 (302)

Polysaccharide Adjuvants as Innate Immune Trainers: Bridging Pattern Recognition Receptor (PRR) Activation and Metabolic Reprogramming for Synthetic Vaccine Design

open access: yesAdvanced Science, Volume 12, Issue 48, December 29, 2025.
Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon   +8 more
wiley   +1 more source

Identifying Key Questions and Challenges in Microchimerism Biology

open access: yesAdvanced Science, Volume 12, Issue 48, December 29, 2025.
This study identifies key unanswered questions about microchimerism, the presence of cells from one individual living in another. Experts highlight how these cells may affect health, pregnancy, and disease. This study outlines research priorities and challenges in detecting and studying these rare microchimeric cells, aiming to guide future discoveries
Kristine J. Chua   +31 more
wiley   +1 more source

Fish Pathogens and Associated Zoonotic Risks in Aquaculture: A Global One Health Perspective

open access: yesAquaculture, Fish and Fisheries, Volume 5, Issue 6, December 2025.
ABSTRACT Aquaculture sector is a key contributor to global food and nutritional security, yet its rapid intensification has heightened concerns about the emergence and spread of zoonotic fish pathogens that threaten human, animal and environmental health.
Fredrick Juma Syanya   +7 more
wiley   +1 more source

One-year vaccination against hepatitis B virus with a MPL-vaccine in liver transplant patients for HBV-related cirrhosis

open access: green, 2010
Daniele Di Paolo   +8 more
openalex   +2 more sources

Innate immunity stimulation effects on biofluid/imaging biomarkers and cognition in a non‐human primate model of sporadic AD pathology

open access: yesAlzheimer's &Dementia, Volume 21, Issue S5, December 2025.
Abstract Background Non‐human primates (NHPs) are becoming a critical component of brain aging research, since many aspects of aging cannot be properly modeled in rodents. Our earlier published study utilizing a NHP model of sporadic AD‐related pathology that develops abundant CAA, the squirrel monkey (SQM), indicated that treatment with TLR9 agonist ...
Noor Salaymeh   +12 more
wiley   +1 more source

Efficacy of Hepatitis B vaccine in those who lost Hepatitis B surface antigen during follow-up: Efficacy of HBV vaccine in those who lost HBsAg.

open access: green, 2011
Hassan Taheri   +4 more
openalex   +1 more source

Silica Nanoparticles as Multifunctional Platforms for Vaccine Delivery and Immune Modulation in Infectious Diseases

open access: yesAdvanced NanoBiomed Research, Volume 5, Issue 12, December 2025.
Overview of the use of silica nanoparticles in vaccines against pathogens. Different kinds of vaccines against infectious diseases are currently using solid or mesoporous silica nanoparticles in their formulation. Silica microparticles and nanoparticles (SiNPs) have been studied as vehicles for vaccines.
Noe Juvenal Mendoza‐Ramírez   +3 more
wiley   +1 more source

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