Results 231 to 240 of about 94,533 (302)

Recent Utilization of Pediatric Extrapolation and Modeling and Simulation Approaches in Pediatric Drug Development in Japan

The Journal of Clinical Pharmacology, Volume 65, Issue 12, Page 1889-1899, December 2025.
Abstract In Japan, the percentage of approved drugs with pediatric indications increased to 30% in 2010‐2015, but no further increase was observed through 2020. The Ministry of Health, Labor, and Welfare in Japan presented draft future directions to promote pediatric drug development, where the modeling and simulation (M&S) approach was introduced as a
Akinori Nakashima, Akihide Tsujimoto, Masako Saito, Jun Takeda, Makiko Natori, Satoshi Shoji   +5 more
wiley   +1 more source

Long‐Term Safety Profile of Ruxolitinib in Chronic Myeloproliferative Neoplasms: A Comprehensive Real‐World Analysis

eJHaem, Volume 6, Issue 6, December 2025.
ABSTRACT Introduction Ruxolitinib is a key therapeutic option for patients with myeloproliferative neoplasms. Its short‐term toxicity profile is well‐established, but long‐term safety data remains scarce. Methods We aimed to evaluate toxicity associated with long‐term exposure to ruxolitinib (defined as 3 years or longer) through a dual‐cohort ...
Alberto Blanco‐Sánchez, Rosa Ayala, Gonzalo Carreño‐Tarragona, Rafael Colmenares, Nieves López‐Muñoz, Adolfo Sáez, María Luisa Palacios‐Berraquero, Julia Hernández, Joaquín Martínez‐López   +8 more
wiley   +1 more source

Systematic Review of Postvaccination Ocular Adverse Events: A Comprehensive Analysis of Published Reports

Journal of Medical Virology, Volume 97, Issue 12, December 2025.
ABSTRACT Ocular adverse events following COVID‐19 vaccination are well described; however, systematic analyses of non‐COVID antiviral vaccines remain limited. This review aimed to evaluate ocular complications associated with non‐COVID antiviral immunizations, including influenza, varicella‐zoster (VZV), human papillomavirus (HPV), and hepatitis B (HBV)
Yaru Zou, Koju Kamoi, Yuan Zong, Jing Zhang, Mingming Yang, Kyoko Ohno‐Matsui   +5 more
wiley   +1 more source

Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.

, 2013
Alireza Janbakhsh, Feizollah Mansouri, Siavash Vaziri, Babak Sayad, Mandana Afsharian, Mehrali Rahimi, Karoon Shahebrahimi, Salari Farham   +7 more
openalex   +1 more source

Optimising Vaccination Status in a Belgian Dermatological Immune‐Mediated Inflammatory Disease Population: An Education‐Based Pro‐Active Patient‐Centred Approach

JEADV Clinical Practice, Volume 4, Issue 5, Page 1033-1038, December 2025.
ABSTRACT Background Patients with dermatological immune mediated inflammatory diseases (IMIDs) are increasingly treated with immunosuppressive and ‐modulating drugs. Some of these drugs increase the risk of acquiring infections and more complications can arise during an infection while treated with these agents.
Femke Lieten, Tine Vanhoutvin, Dorien Hunin, Céline Vanvelk, Liesbeth Gilissen, Petra De Haes, An Van Laethem, Francisca Castelijns, Tom Hillary   +8 more
wiley   +1 more source

Introducing adjuvant-loaded particulate hepatitis B core antigen as an alternative therapeutic hepatitis B vaccine component. [PDF]

JHEP Rep
Su J, Harati Taji Z, Kosinska AD, Ates Oz E, Xie Z, Bielytskyi P, Shein M, Hagen P, Esmaeili S, Steiger K, Protzer U, Schütz AK.   +11 more
europepmc   +1 more source

Hepatitis B vaccine uptake and associated factors among adults of Gulu city in Northern Uganda: A community-based cross-sectional study. [PDF]

PLoS One
Aber JO, Bongomin F, Opio SL, Ochola E.
europepmc   +1 more source

Health Facility Capacity and Health-care Worker Knowledge, Attitudes, and Practices of Hepatitis B Vaccine Birth-dose and Maternal Tetanus-Diphtheria Vaccine Administration in Nigeria: A Baseline Assessment.

Ann Afr Med
Uba BV, Mohammed Y, Nwokoro UU, Fadahunsi R, Adewole A, Ugbenyo G, Simple E, Wisdom MO, Waziri NE, Michael CA, Okeke LA, Kanu F, Ikwe H, Sandhu HS, Asekun A, Tohme RA, Freeland C, Minta A, Bashir SS, Isa A, Vasumu JJ, Bahuli AU, Ugwu GO, Obi EI, Ismail BA, Okposen BB, Bolu OO, Shuaib F.   +27 more
europepmc   +1 more source