Results 231 to 240 of about 364,170 (283)

Escherichia coli in the production of biopharmaceuticals

Biotechnology and Applied Biochemistry, Volume 72, Issue 2, Page 528-541, April 2025.
Abstract Escherichia coli has shouldered a massive workload with the discovery of recombinant DNA technology. A new era began in the biopharmaceutical industry with the production of insulin, the first recombinant protein, in E. coli and its use in treating diabetes. After insulin, many biopharmaceuticals produced from E. coli have been approved by the
İbrahim İncir, Özlem Kaplan
wiley   +1 more source

Hepatitis B vaccine effectiveness among vaccinated children in Africa: a systematic review and meta-analysis. [PDF]

BMC Pediatr
Geta M, Yizengaw E, Manyazewal T.
europepmc   +1 more source

Dual‐Stage Cross‐Flow Filtration: Integrated Capture and Purification of Virus‐Like Particles

Biotechnology and Bioengineering, Volume 122, Issue 4, Page 884-894, April 2025.
An innovative dual‐stage cross‐flow filtration (CFF) setup is presented to capture and purify virus‐like particles (VLP). Coupling two CFF units and using a 2 µm/300 kDa MWCO membrane configuration allows for selective VLP precipitation and washing of the precipitate in the first membrane stage combined with subsequent, simultaneous recovery, isolation,
Annabelle Dietrich, Luca Heim, Jürgen Hubbuch   +2 more
wiley   +1 more source

The Role of Cholesterol Metabolism and Its Regulation in Tumor Development

Cancer Medicine, Volume 14, Issue 7, April 2025.
ABSTRACT Background Within the tumor microenvironment, tumor cells undergo metabolic reprogramming of cholesterol due to intrinsic cellular alterations and changes in the extracellular milieu. Furthermore, cholesterol reprogramming within this microenvironment influences the immune landscape of tumors, facilitating immune evasion and consequently ...
Yongmei Wu, Wenqian Song, Min Su, Jing He, Rong Hu, Youbo Zhao   +5 more
wiley   +1 more source

Advances in the Prevention of Cervical Cancer by Anti‐Human Papillomavirus Agents

Cancer Medicine, Volume 14, Issue 7, April 2025.
ABSTRACT Background Cervical cancer remains a major global health threat for women, primarily driven by human papillomavirus (HPV) infection. While HPV vaccination serves as the cornerstone of prevention, disparities in vaccine accessibility persist across low‐income countries.
Hangdi Chen, Kai Guo, Zhihao Bai, Liuyi Lu, Bin Liu, Jiali Zhang, Meiyin Zhong, Changfen Xu, Wanghuan Chen, Aiwu Huang, Yuemin Ding   +10 more
wiley   +1 more source

Immune response to hepatitis B vaccine among children under 5 years in Africa: a meta-analysis. [PDF]

Trop Med Health
Olakunde BO, Ifeorah IM, Adeyinka DA, Olakunde OA, Ogundipe T, Olawepo JO, Ezeanolue EE.   +6 more
europepmc   +1 more source

Fulminant Type 1 Diabetes Mellitus With Concomitant Coxsackievirus B6 Antibody Elevation and RNA‐Based COVID‐19 Vaccination: A Case Report and Review of the Literature

Clinical Case Reports, Volume 13, Issue 4, April 2025.
ABSTRACT Fulminant type 1 diabetes is a rare but severe condition that can develop rapidly, often in association with viral infections. In this case, coxsackievirus B6 antibody levels were elevated after disease onset, though its significance remains unclear.
Hisaka Minami, Shinya Furukawa, Teruki Miyake, Keisho Kurokawa, Yasuhiro Sasaki, Masayuki Nakaishi, Kensuke Nagamatsu, Hiroka Yamago, Naozumi Shibata, Yoichi Hiasa, Bunzo Matsuura   +10 more
wiley   +1 more source

Considerations for hepatitis B as part of a combination vaccine

, 2001
David P. Greenberg
openalex   +1 more source

Current Advancements in Serum Protein Biomarkers for Hepatitis B Virus‐Associated Hepatocyte Remodeling and Hepatocellular Carcinoma

Immunity, Inflammation and Disease, Volume 13, Issue 4, April 2025.
ABSTRACT Background Hepatitis B virus (HBV)‐related liver cancer is the third most common cause of cancer‐related death globally. Hepatocyte remodeling, also known as hepatocyte transformation and immortalization, and hepatocellular carcinoma (HCC), are brought on by persistent inflammation caused by HBV in the host hepatocytes.
Adane Adugna, Gashaw Azanaw Amare, Mohammed Jemal   +2 more
wiley   +1 more source

Hepatitis B Vaccine Refusal Trends in Washington, DC, Newborns, 2017-2022.

JAMA Netw Open
Yang YT, Leslie TF, Delamater PL.
europepmc   +1 more source