Results 241 to 250 of about 364,170 (283)

Knowledge of hepatitis B infection, hepatitis B vaccine, and vaccination status with its associated factors among healthcare workers in Kampot and Kep Provinces, Cambodia. [PDF]

BMC Infect Dis
Sok S, Chhoung C, Sun B, Ko K, Sugiyama A, Akita T, Fukuma S, Tanaka J.   +7 more
europepmc   +1 more source

Altered Circulating Cytokine Profile Among mRNA‐Vaccinated Young Adults: A Year‐Long Follow‐Up Study

Immunity, Inflammation and Disease, Volume 13, Issue 4, April 2025.
ABSTRACT Objectives This longitudinal study aimed to assess the impact of COVID‐19 vaccination on cytokine profile. Methods A total of 84 Saudi subjects (57.1% females) with mean age of 27.2 ± 12.3 participated in this longitudinal study. Anthropometric data and fasting blood samples were obtained at baseline and after final vaccination, with an ...
Amani Alghamdi, Syed Danish Hussain, Kaiser Wani, Shaun Sabico, Abdullah M. Alnaami, Osama Emam Amer, Nasser M. Al‐Daghri   +6 more
wiley   +1 more source

Risk of Serious Infections in Patients Treated With Biologic or Targeted‐synthetic Disease Modifying Antirheumatic Drugs in Qatar

Immunity, Inflammation and Disease, Volume 13, Issue 4, April 2025.
This study investigates the risk of serious infections (SIs) in patients treated with biologic or targeted‐synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) in Qatar. Out of 1092 patients, 86 (7.9%) experienced SIs, with adalimumab and infliximab associated with higher SI rates.
Sreethish Sasi, Hamad Abdel Hadi, Masautso Chaponda, Reem El Ajez, Mohamed Ataelmanan, Sief Khasawneh, Hind Saqallah, Maisa Ali, Nabeel Abdulla, Javed Iqbal, Ali S. Omrani, Muna Al Maslamani, Abdullatif Al‐Khal   +12 more
wiley   +1 more source

Immune Checkpoint Molecules: A Review on Pathways and Immunotherapy Implications

Immunity, Inflammation and Disease, Volume 13, Issue 4, April 2025.
Immune checkpoint molecules are today's leading targets for immunotherapy, especially in the field of cancer. This review summarizes the most important and recent advances in this field and in different types of cancer. ABSTRACT Background Today, treating cancer patients with monoclonal antibodies (mAbs), by targeting immune checkpoints, is one of the ...
Erfan Rezazadeh‐Gavgani, Reza Majidazar, Parisa Lotfinejad, Tohid Kazemi, Ali Shamekh   +4 more
wiley   +1 more source

Real World Management of Cytopenias and Infections in Patients With Myelofibrosis Treated With Ruxolitinib

eJHaem, Volume 6, Issue 2, April 2025.
ABSTRACT Introduction Ruxolitinib was the first JAK2 inhibitor approved for the treatment of primary and secondary myelofibrosis. It is currently used worldwide as first‐line therapy for advanced disease (intermediate‐2 and high‐risk) and is effective in polycythaemia vera (PV) and essential thrombocythaemia (ET), but not funded for this indication in ...
Liesl A. Butler, Cecily Forsyth, Claire Harrison, Andrew C. Perkins   +3 more
wiley   +1 more source

Beyond Childhood: Adult and Adolescent Sickle Cell Disease and Outcomes in Northern Ghana

eJHaem, Volume 6, Issue 2, April 2025.
ABSTRACT Background Adults and adolescents face different barriers to healthcare utilization compared to children. Objective To describe adult and adolescent sickle cell disease (SCD) and outcomes in northern Ghana. Methods This was a retrospective cohort study of SCD patients aged 13 years and above, admitted between January 1, 2021 and December 31 ...
Kwadwo Faka Gyan, Solomon Gyabaah, Eunice Agyeman Ahmed, Lesley Osei, Mohammed Najeeb Naabo, Michael Asiedu Owiredu, Yaw Obeng Opare‐Addo, Jessey Mahama Holu, Ohene Kwaku Opare‐Sem   +8 more
wiley   +1 more source

Age‐Stratified Treg Responses During Viral Infections of the Central Nervous System: A Literature Review

Journal of Medical Virology, Volume 97, Issue 4, April 2025.
ABSTRACT Regulatory T cells (Tregs) play a vital role in limiting inflammation and resolving the immune response after a viral infection. Within the central nervous system (CNS), Tregs are especially important for the protection of neurons, which have limited regenerative capacity, and the preservation of myelin sheaths, which support neuronal function
Vivek R. Singh, Lauren A. O'Donnell
wiley   +1 more source

A Phase I Study Evaluating Safety and Tolerability of Viral‐Specific T Cells Against BK‐Virus in Adult Kidney Transplant Recipients

Journal of Medical Virology, Volume 97, Issue 4, April 2025.
ABSTRACT BK polyomavirus (BKPyV) poses a significant threat to kidney transplant recipients (KTR). Current management primarily involves reducing immunosuppression, which increases the risk of rejection. Cell‐based immunotherapy with virus‐specific T cells (VST) has emerged as an alternative approach for treating BKPyV in KTRs. This single‐center phase
Lucy Ptak, Ross O. Meyers, Olga Radko‐Ganz, Kimberly A. McDowell, Margaret Jorgenson, Maggie Chilsen, Didier Mandelbrot, Jacques Galipeau, Sandesh Parajuli   +8 more
wiley   +1 more source

Hepatitis B vaccine uptake and associated factors among adults of Gulu city in Northern Uganda: A community-based cross-sectional study. [PDF]

PLoS One
Aber JO, Bongomin F, Opio SL, Ochola E.
europepmc   +1 more source

Development and launch of a regional learning network to improve physical and mental health outcomes

Learning Health Systems, Volume 9, Issue 2, April 2025.
Abstract Background Care gaps in routine and preventive care are common among youth. To close care gaps, health systems should take a population health approach and create opportunities for partnership, collaboration, shared learning, and scale via learning networks (LNs).
Ndidi Unaka, Jeff Steller, Sarah Eaton, Brandy Seger, Jessica M. McClure, Mona Mansour, Kate Rich, Andrew F. Beck, Mary Carol Burkhardt, Nicole Lacasse, Crystal Robinson, Jeff Anderson   +11 more
wiley   +1 more source