Results 251 to 260 of about 387,869 (336)

Early IL‐1 Inhibition in Still's Disease: A Window of Opportunity for Improving Outcomes

open access: yesACR Open Rheumatology, Volume 7, Issue 10, October 2025.
Objective Still's disease is a complex, multisystemic disorder requiring prompt diagnosis and treatment. This study provides a general assessment of a Still's disease cohort aiming to evaluate the efficacy of early intervention with interleukin‐1 inhibitors (IL‐1i) in achieving clinical inactive disease (CID) and reducing glucocorticoid use in patients
Sara Bindoli   +5 more
wiley   +1 more source

Immune response to hepatitis B vaccine among children under 5 years in Africa: a meta-analysis. [PDF]

open access: yesTrop Med Health
Olakunde BO   +6 more
europepmc   +1 more source

From Lab to Market: Paper‐Based CRISPR Diagnostics and Commercialization Pathways

open access: yesAdvanced Sensor Research, Volume 4, Issue 10, October 2025.
Paper‐based CRISPR diagnostics represents one of the most widely commercialized CRISPR assay technologies, yet challenges remain for broader point‐of‐care use. Abstract The global health landscape is continually challenged by infectious diseases that can swiftly escalate into pandemics, underscoring the need for rapid, accurate, and cost‐effective ...
Selen Dalgan, Qingshan Wei
wiley   +1 more source

Hepatitis B Vaccine Refusal Trends in Washington, DC, Newborns, 2017-2022.

open access: yesJAMA Netw Open
Yang YT, Leslie TF, Delamater PL.
europepmc   +1 more source

NamiRNA‐Enhancer Network: The Changing Era Challenge and Chance of miRNA

open access: yesAdvanced Science, Volume 12, Issue 39, October 20, 2025.
MiRNAs (miRNAs) regulate diverse biological processes across species. Unlike canonical miRNA‐mediated gene repression, Nuclear Activating miRNAs (NamiRNAs) can efficiently upregulate gene expression by targeting enhancers. This review systematically summarizes recent advances in NamiRNA research, elucidates the theory of NamiRNA‐Enhancer‐mediated Gene ...
Lu Chen   +13 more
wiley   +1 more source

Neopterin as a Tool for Primate Ecoimmunology: Current Knowledge, Practical Application, and New Directions From Captivity to the Wild

open access: yesAmerican Journal of Primatology, Volume 87, Issue 10, October 2025.
Neopterin is a sensitive and specific biomarker of intracellular pathogen infection and chronic inflammation, and affected by environmental, life‐history, and sex‐contextual factors. This review offers best‐practice guidelines and practical advice on sample collection, storage, and analysis in primates when used for ecoimmunological conservation and ...
Verena Behringer, Caroline Deimel
wiley   +1 more source

A Case of Vitreous Hemorrhage Possibly Attributable to Retinal Arterial Microaneurysm Following SARS‐CoV‐2 Vaccination

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Vitreous hemorrhage caused by a ruptured retinal arterial microaneurysm can occur in patients with diabetic retinopathy after severe acute respiratory syndrome coronavirus 2 vaccination.
Tatsuya Sakamoto   +8 more
wiley   +1 more source

CRISPR‐driven diagnostics: Molecular mechanisms, clinical efficacy and translational challenges

open access: yesClinical and Translational Medicine, Volume 15, Issue 10, October 2025.
The CRISPR/Cas system has emerged as a transformative tool in the field of molecular diagnosis, offering unprecedented sensitivity, specificity and rapid detection capabilities. This review further examines the molecular mechanisms of CRISPR tools, compares their clinical efficacy with traditional methods and highlights cutting‐edge innovations such as
Zilong Wang   +7 more
wiley   +1 more source

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