Results 61 to 70 of about 397,978 (363)

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

Prediction of strain engineerings that amplify recombinant protein secretion through the machine learning approach MaLPHAS

open access: yesEngineering Biology, Volume 6, Issue 4, Page 82-90, December 2022., 2022
Abstract This article presents a discussion of the process of precision fermentation (PF), describing the history of the space, the expected 70% growth over the next 5 years, various applications of precision fermented products, and the markets available to be disrupted by the technology. A range of prokaryotic and eukaryotic host organisms used for PF
Evgenia A. Markova   +2 more
wiley   +1 more source

Harnessing Nanohybridized Niclosamide for Precision Mpox Therapeutics

open access: yesAdvanced Healthcare Materials, EarlyView.
This study investigates the potential of nanohybridized niclosamide as a therapeutic agent for Mpox, focusing on enhanced bioavailability, improved antiviral efficacy, and controlled drug release achieved through nanoengineering. The research emphasizes significant advancements in formulation strategies, mechanistic insights, and therapeutic outcomes ...
N. Sanoj Rejinold   +2 more
wiley   +1 more source

Enhanced vaccine control of epidemics in adaptive networks [PDF]

open access: yes, 2009
We study vaccine control for disease spread on an adaptive network modeling disease avoidance behavior. Control is implemented by adding Poisson distributed vaccination of susceptibles. We show that vaccine control is much more effective in adaptive networks than in static networks due to an interaction between the adaptive network rewiring and the ...
arxiv   +1 more source

BlockColdChain: Vaccine Cold Chain Blockchain [PDF]

open access: yesarXiv, 2021
In this paper, we propose a blockchain-based cold chain technology for vaccine cooling track. The COVID-19 pandemic has caused the death of millions of people. An important step towards ending the pandemic is vaccination. Vaccines must be kept under control temperature during the whole process, from fabrication to the hands of the health professionals ...
arxiv  

Vaccine Policy in India [PDF]

open access: yes, 2005
India enjoyed early initial successes in vaccine development and indigenous production of vaccines in the public sector.
Bhargava   +8 more
core   +3 more sources

Universal Prophylactic Antitumor Vaccination Using Stem Cell Membrane‐Coated Nanoparticles

open access: yesAdvanced Materials, EarlyView.
Induced pluripotent stem cell membrane is coated onto adjuvant‐loaded nanoparticle cores to create a universal cancer vaccine. The formulation utilizes oncofetal antigens present on the cell membrane to elicit broadly protective immune responses in vivo.
Nishta Krishnan   +10 more
wiley   +1 more source

Vitamin D—A prominent immunomodulator to prevent COVID‐19 infection

open access: yesInternational Journal of Rheumatic Diseases, Volume 26, Issue 1, Page 13-30, January 2023., 2023
Abstract COVID‐19 remains a life‐threatening infectious disease worldwide. Several bio‐active agents have been tested and evaluated in an effort to contain this disease. Unfortunately, none of the therapies have been successful, owing to their safety concerns and the presence of various adverse effects.
Sumel Ashique   +13 more
wiley   +1 more source

Removing N-terminal sequences in pre-S1 domain enhanced antibody and B-cell responses by an HBV large surface antigen DNA vaccine. [PDF]

open access: yesPLoS ONE, 2012
Although the use of recombinant hepatitis B virus surface (HBsAg) protein vaccine has successfully reduced global hepatitis B infection, there are still a number of vaccine recipients who do not develop detectable antibody responses.
Guohong Ge   +5 more
doaj   +1 more source

Semiparametric logistic regression for inference on relative vaccine efficacy in case-only studies with informative missingness [PDF]

open access: yesarXiv, 2023
We develop semiparametric methods for estimating subgroup-specific relative vaccine efficacy against multiple viral strains in a partially vaccinated population. Focusing on observational case-only studies, we address informative missingness in strain type due to vaccination status, pre-vaccination characteristics, and post-infection factors such as ...
arxiv  

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