Results 81 to 90 of about 127,319 (303)

Comorbidities in aging patients with sickle cell disease. [PDF]

, 2018
Sickle cell disease (SCD) in general and sickle cell anemia in particular is a highly complex disorder both at the molecular and clinical levels. Although the molecular lesion is a single-point mutation, the sickle gene is pleiotropic in nature causing ...
Ballas, Samir K.
core   +2 more sources

A Multivalent mRNA Therapeutic Vaccine Exhibits Breakthroughs in Immune Tolerance and Virological Suppression of HBV by Stably Presenting the Pre-S Antigen on the Cell Membrane

Pharmaceutics
Background/Objectives: In chronic hepatitis B infection (CHB), the hepatitis B surface antigen (HBsAg) continuously exhausts the hepatitis B surface antibody (HBsAb), which leads to the formation of immune tolerance.
Shang Liu, Jie Wang, Yunxuan Li, Muhan Wang, Pei Du, Zhijie Zhang, Wenguo Li, Rongchen Sun, Mingtao Fan, Meijia Yang, Hongping Yin   +10 more
doaj   +1 more source

Problems of the Current Vaccination Strategy against Hepatitis B

Эпидемиология и вакцинопрофилактика, 2017
Accumulation of escape mutants of hepatitis B virus (HBV) occur in the many countries at the conditions of wide-scale vaccination against hepatitis B, especially among vaccinated children.
M. V. Konopleva, V. N. Borisova, T. A. Semenenko, M. A. Krymskij   +3 more
doaj   +1 more source

Long-term moderate calorie restriction inhibits inflammation without impairing cell-mediated immunity: A randomized controlled trial in non-obese humans [PDF]

, 2016
Calorie restriction (CR) inhibits inflammation and slows aging in many animal species, but in rodents housed in pathogen-free facilities, CR impairs immunity against certain pathogens.
Bhapkar, Manjushri, Das, Sai K, Dixit, Vishwa D, Fontana, Luigi, Fuss, Paul J, Gupta, Alok K, Holloszy, John O, Huang, Megan, Klein, Sam, Lewis, Michael R, Meydani, Simin N, Pieper, Carl F, Roberts, Susan B, Villareal, Dennis T   +13 more
core   +2 more sources

Completion of multiple-dose travel vaccine series and the availability of pharmacist immunizers: A retrospective analysis of administrative data in Alberta, Canada.

PLoS ONE, 2019
Pharmacists in a number of countries are being trained in the administration of injections with the aim of improving access and adherence to vaccinations.
Sherilyn K D Houle, Dean T Eurich
doaj   +1 more source

Recombinant Flag-tagged E1E2 glycoproteins from three hepatitis C virus genotypes are biologically functional and elicit cross-reactive neutralizing antibodies in mice [PDF]

, 2018
Hepatitis C virus (HCV) is a globally disseminated human pathogen for which no vaccine is currently available. HCV is highly diverse genetically and can be classified into 7 genotypes and multiple sub-types. Due to this antigenic variation, the induction
Bieńkowska-Szewczyk, Krystyna, Chmielewska, Alicja, Krapchev, Vasil B., Patel, Arvind H., Rychłowska, Malgorzata, Zimmer, Karolina   +5 more
core   +1 more source

Supra and subgingival application of antiseptics or antibiotics during periodontal therapy

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero, Jorge Serrano, Nicole Birgit Arweiler, Thorsten Mathias Auschill, Ali Gürkan, Gülnur Emingil   +5 more
wiley   +1 more source

Booster Vaccination Against Invasive Pneumococcal Disease and Hepatitis B in Previously Vaccinated Solid Organ Transplant Recipients Without Seroprotection

Vaccines
Background: Despite pre-transplantation vaccination against invasive pneumococcal disease (IPD) and hepatitis B virus (HBV), most solid organ transplant (SOT) recipients are without post-transplantation seroprotection against IPD and HBV.
Julie Sejerøe-Olsen, Moises Alberto Suarez-Zdunek, Thomas Helbo, Lise Bank Hornung, Charlotte Sværke Jørgensen, Kasper Rossing, Michael Perch, Allan Rasmussen, Sebastian Rask Hamm, Susanne Dam Nielsen   +9 more
doaj   +1 more source

Vaccination in the setting of sexually transmitted infections consultation

Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2023
Sexually transmitted infections (STIs) are a significant public health concern across the globe. Vaccines have played a crucial role in mitigating the burden of infectious diseases and are the most effective candidates for preventing STIs.
Lanyu Sun, Claúdia Brazão, Dora Mancha, Diogo de Sousa, João Borges-da-Costa   +4 more
doaj  

Modern View on the Problem of Choosing a Vaccine against Hepatitis B

Эпидемиология и вакцинопрофилактика, 2017
The problem of the discrepancy between serotypes of the circulating strains of hepatitis B virus and serotype of the HBsAg in the vaccine is discussed. The results of published scientific studies show that hepatitis B vaccines containing HBsAg serotype ...
V. P. Chulanov, T. A. Semenenko, I. V. Karandashova, S. V. Komarova, D. S. Kostyushev, A. P. Suslov, E. V. Volchkova   +6 more
doaj   +1 more source