Results 71 to 80 of about 130,240 (311)
PreHevbrio: the first approved 3-antigen hepatitis B vaccine
Introduction Hepatitis B remains a major cause of death and morbidity worldwide. Universal childhood immunization programs have been very successful, but many adults remain unprotected or are not optimally protected.
Timo Vesikari +3 more
doaj +1 more source
Comorbidities in aging patients with sickle cell disease. [PDF]
Sickle cell disease (SCD) in general and sickle cell anemia in particular is a highly complex disorder both at the molecular and clinical levels. Although the molecular lesion is a single-point mutation, the sickle gene is pleiotropic in nature causing ...
Ballas, Samir K.
core +2 more sources
Prevention of hepatocellular carcinoma: a concise review of contemporary issues
Hepatocellular carcinoma (HCC) is the fifth most common cancer and the second leading cause of cancer deaths in men. Due to differences in the prevalence of viral hepatitis, the incidence of HCC in low and middle income countries is much higher than that
Vincent Wai-Sun Wong +1 more
doaj +1 more source
What's New? This study quantified the cancer burden attributable to modifiable risk factors in Guangdong, the most populous and economically advanced province in southern China. By evaluating 15 modifiable risk factors, the study reveals that over one‐third of cancer cases and two‐fifths of cancer deaths in the region could potentially be prevented ...
Xiaolan Wen +17 more
wiley +1 more source
Recombinant Flag-tagged E1E2 glycoproteins from three hepatitis C virus genotypes are biologically functional and elicit cross-reactive neutralizing antibodies in mice [PDF]
Hepatitis C virus (HCV) is a globally disseminated human pathogen for which no vaccine is currently available. HCV is highly diverse genetically and can be classified into 7 genotypes and multiple sub-types. Due to this antigenic variation, the induction
Bieńkowska-Szewczyk, Krystyna +5 more
core +1 more source
Еhe announcement of the east European expert group for vaccine prevention presents position of the leading specialists of Russia, Belarus, Ukraine and Kazakhstan on key issues of the national pre vention immunization schedule.
A.A. Baranov +10 more
doaj +2 more sources
Fertility and Early Embryonic Development Toxicity of hzVSF‐v13 in Sprague–Dawley Rats
ABSTRACT Humanized virus suppressing factor–variant 13 (hzVSF‐v13), a monoclonal IgG4 antibody, is a potential therapeutic candidate for COVID‐19. Although fertility and embryonic developmental toxicity studies are crucial for the safety evaluation of new drugs, the toxicological profile of hzVSF‐v13 remains unexplored.
Ji‐Seong Jeong +10 more
wiley +1 more source
Factors Associated with Immunization Opinion Leadership among Men Who Have Sex with Men in Los Angeles, California [PDF]
We sought to identify the characteristics of men who have sex with men (MSM) who are opinion leaders on immunization issues and to identify potential opportunities to leverage their influence for vaccine promotion within MSM communities.
Bednarczyk, Robert +9 more
core +3 more sources
ABX203, a novel therapeutic vaccine for chronic hepatitis B patients
Despite the existence of effective prophylactic vaccines, chronic hepatitis B remains a major public health problem, with more than 350 million people infected worldwide.
Y. Lobaina Mato +2 more
doaj +1 more source
Abstract In Japan, the percentage of approved drugs with pediatric indications increased to 30% in 2010‐2015, but no further increase was observed through 2020. The Ministry of Health, Labor, and Welfare in Japan presented draft future directions to promote pediatric drug development, where the modeling and simulation (M&S) approach was introduced as a
Akinori Nakashima +5 more
wiley +1 more source

