Results 71 to 80 of about 397,978 (363)

Teenagers’ understandings of and attitudes towards vaccines and vaccine-preventable diseases: a qualitative study [PDF]

, 2013
<p>Background: To examine immunisation information needs of teenagers we explored understandings of vaccination and vaccine-preventable diseases, attitudes towards immunisation and experiences of immunisation.
Barbour, Bedford, Bloor, Bond, Brabin, Brownlie, Butler, Bynum, C. Patterson, Clark, Crocker, Duffell, E. Smith, Finn, Flynn, Gellin, Gordon, H. Bedford, Hilton, Hilton, Hilton, Hinds, Hobson-West, K. Hunt, Kale, Kitzinger, Lashkari, Maple, Marlow, Miller, Paranthaman, Pareek, Parrella, Peckham, Pelucchi, Pollard, Poltorak, Ramsay, Ritchie, S. Hilton, Slonim, Smailbegovic, Smith, Sporton, Streefland, Stretch, Woodhall, Yarwood, Zimet   +48 more
core   +1 more source

Achieving Optimal Health With Host‐Directed Therapies (HDTs) in Infectious Diseases—A New Horizon

Advanced Therapeutics, EarlyView.
Host‐directed therapies (HDTs) represent a transformative approach in infectious disease management by targeting host factors to enhance immune responses and inhibit viral replication. This innovative strategy leverages advanced genomics and gene editing technologies, offering promising avenues for improved patient outcomes and a new horizon in ...
Amol D. Gholap, Pankaj R. Khuspe, Sagar R. Pardeshi, Md Jasim Uddin, Ushasi Das, Navnath T. Hatvate, Satish Rojekar, Prabhanjan Giram, Mohammad Khalid, Yahya E. Choonara, Md. Faiyazuddin   +10 more
wiley   +1 more source

Het Rijksvaccinatieprogramma in Nederland. Ontwikkelingen in 2006 [PDF]

, 2007
In 2006 several changes were made in the Dutch National Immunisation Programme (NIP): Hepatitis B vaccination at birth was added for children born to mothers positive for hepatitis B surface antigen; a new vaccine for diphtheria, tetanus, pertussis (a ...
Abbink F, Avoort HGAM van der, Berbers WAM, Binnendijk RS van, Boot HJ, Duynhoven YTHP van, Geraedts JLE, Gerritsen AAM, Greeff SC de, Hahne SJM, Hofhuis A, Kemmeren JM, Kimman TG, Klein MR, Koedijk FDH, Koopmans MPG, Kremer K, Maas NAT van der, Mangen MJJ, Meijer A, Mooi FR, Mylius SD, Notermans DW, Op de Coul ELM, Sande MAB van der, Schouls LM, Soolingen D van, Steenbergen JE van, Vermeer-de Bondt PE, Wallinga J, Wit GA de   +30 more
core  

Immunogenicity and immunization costs of adjuvanted versus non-adjuvanted hepatitis B vaccine in chronic kidney disease patients [PDF]

, 2016
Hepatitis B virus (HBV) vaccination is recommended for all susceptible chronic pre-hemodialysis and hemodialysis patients. This study assessed the immunogenicity of HBV vaccines (adjuvanted and non ...
Aldea, Marta, Bayas Rodríguez, José María, García-Basteiro, Alberto L., Sequera, Víctor Guillermo, Sicuri, Elisa, Velasco Muñoz, César, Vilajeliu, Alba   +6 more
core   +1 more source

Insights into the Dynamics and Binding Mechanisms of the Alkhumra Virus NS2B/NS3 Protease: A Molecular Dynamics Study

Advanced Theory and Simulations, EarlyView.
The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak, Shivananda Kandagalla, Ramesh Sistla   +2 more
wiley   +1 more source

Combination vaccines

Journal of Global Infectious Diseases, 2011
The combination of diphtheria, tetanus, and pertussis vaccines into a single product has been central to the protection of the pediatric population over the past 50 years.
David AG Skibinski, Barbara C Baudner, Manmohan Singh, Derek T O′Hagan   +3 more
doaj   +1 more source

Antigen‐Targeting Inserted Nanomicelles Guide Pre‐Existing Immunity to Kill Head and Neck Cancer

Advanced Science, EarlyView.
This study introduces a tumor‐targeted nanomicelle platform (preS1‐pHLIP) that exploits pre‐existing antiviral immunity to combat heterogeneous cancers. By delivering viral antigens to label tumors as virus‐like targets, the nanomicelles activate antiviral B and T cells, triggering in situ tumor lysis.
Lizhuo Zhang, Qingqing Feng, Chuanming Zheng, Yuanqiang Li, Xinyang Ge, Tiefeng Jin, Gaofeng Hu, Zhuo Tan, Jiafeng Wang, Jiajie Xu, Liehao Jiang, Dan Wang, Zhangguo Ying, Xiao Zhao, Keman Cheng, Qinglin Li, Minghua Ge   +16 more
wiley   +1 more source

Hepatitis B virus movement through the hepatocyte: An update

Biology of the Cell, Volume 114, Issue 12, Page 325-348, December 2022., 2022
Model of intracellular trafficking routes of progeny hepatitis B virus (HBV) viral and subviral particles through the liver cell involving nucleocytoplasmic shuttling, movement through the ER/Golgi secretory pathway, and budding and release through the multivesicular body (MVB) and/or secretory autophagosomes (sAP) axis.
Reinhild Prange
wiley   +1 more source

CpG‐Based Nanovaccines Enhance Ovarian Cancer Immune Response by Gbp2‐Mediated Remodeling of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CpG‐based nanovaccines bolster ovarian cancer immunotherapy via the Gbp2‐Pin1‐NFkB pathway‐mediated reprogramming of tumor‐associated macrophages (TAMs.) Moreover, this nanovaccine can alleviate chemotherapy‐induced immunosuppression by augmenting the proportion of M1‐like TAMs, enhancing the infiltration of CD8+ T cells, and downregulating the ...
Jiaqiang Xiong, Juyuan Huang, Hanxiao Xu, Qiuji Wu, Jiahui Zhao, Yurou Chen, Guanlan Fan, Haotong Guan, Rourou Xiao, Zhaojin He, Siqi Wu, Wenliang Ouyang, Shixuan Wang, Lu Zhang, Peng Xia, Wei Zhang, Meng Wu   +16 more
wiley   +1 more source

Current progress in the development of therapeutic vaccines for chronic hepatitis B virus infection [PDF]

Iranian Journal of Basic Medical Sciences, 2016
Chronic hepatitis B is still a major public health issue despite the successful prophylactic vaccination attempts. Chronicity of hepatitis B virus(HBV) is mainly due to its ability to debilitate host's immune system.
Faezeh Ghasemi, Sina Rostami, Majid Ghayour-Mobarhan, Zahra Meshkat   +3 more
doaj