Results 101 to 110 of about 606,113 (313)

Occult hepatitis B infection among vaccinated cohort [PDF]

, 2013
BACKGROUND: Occult hepatitis B is characterized by undetectable levels of surface antigen, but detectable levels of viral DNA and is becoming a major global threat due to: (i) the effect on the health of children born to carrier mothers despite the ...
A. Malik, Yasmin, Mohammed Harmal, Nabil Saad, Mohd Taib, Niazlin, Sekawi, Zamberi, Shuaibu, Hudu Abdullahi   +4 more
core   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

Liver disease during pregnancy: acute viral hepatitis

Annals of Hepatology, 2006
Acute viral hepatitis is the most common cause of jaundice in pregnancy. The course of most viral hepatitis infections (e.g., hepatitis A, B, C and D) is unaffected by pregnancy, however, a more severe course of viral hepatitis in pregnancy has been ...
Silvia Sookoian
doaj   +1 more source

Reversion of anergy signatures in clonal CD21low B cells of mixed cryoglobulinemia after clearance of HCV viremia. [PDF]

, 2017
Hepatitis C virus (HCV) causes mixed cryoglobulinemia (MC) by driving clonal expansion of IgM+CD27+ B cells. These cells display both the features of anergy induced by continual engagement of the B cell receptor (BCR), such as high expression of ...
Casato, Milvia, Colantuono, Stefania, DEL PADRE, Martina, Fiorilli, Massimo, Marrapodi, Ramona, Mitrevski, Milica, Todi, Laura, Visentini, Marcella   +7 more
core   +1 more source

Conversion of Transplanted Mature Hepatocytes into Afp+ Reprogrammed Cells for Liver Regeneration After Injury

Advanced Science, EarlyView.
Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang, Chao Yang, Hua Qiu, Yuan Du, Xicheng Wang, Yuting Li, Mingyang Xu, Changcheng Liu, Xiuhua Li, Na Guo, Jun Shi, Wencheng Zhang, Zhiying He   +12 more
wiley   +1 more source

Hepatitis B and C infections, and co-infections screening among patients attending a tertiary hospital in Addis Ababa, Ethiopia: a retrospective database study

BMC Gastroenterology
Background Hepatitis B and C virus infection is a continuous public health problem in Ethiopia, with the prevalence of the disease significantly varying across administrative regions.
Balew Arega, Ermiyas Tefera, Kibrom Mesfin, Daniel Achame, Dawit Tolossa, Abenezer Worku, Ermias Kibru, Nebyu Tafasse, Amdemeskel Mersha   +8 more
doaj   +1 more source

Viral hepatitis in female sex workers using the Respondent-Driven Sampling

Revista de Saúde Pública
OBJECTIVE To estimate the prevalence of hepatitis B virus and C virus infections and their genotypes and analyze the risk factors for the markers of exposure to hepatitis B virus in female sex workers in a region of intense sex trade.
Marcos André de Matos, Divânia Dias da Silva França, Megmar Aparecida dos Santos Carneiro, Regina Maria Bringel Martins, Lígia Regina Franco Sansigolo Kerr, Karlla Antonieta Amorim Caetano, Raquel Silva Pinheiro, Lyriane Apolinário de Araújo, Rosa Maria Salani Mota, Marcia Alves Dias de Matos, Ana Rita Coimbra Motta-Castro, Sheila Araújo Teles   +11 more
doaj   +1 more source

Central obesity and advanced liver stiffness in Hepatitis B: Result from golestan hepatitis B cohort study [PDF]

, 2015
Background: Chronic infection with the hepatitis B virus and obesity may both contribute synergistically to liver disease, although relatively few studies have investigated this hypothesis.
Besharat, S., Freedman, N.D., Malekzadeh, R., Merat, S., Mohamadkhani, A., Poustchi, H., Roshandel, G.   +6 more
core  

CLINICAL RELEVANCE OF PRECORE MUTATIONS OF HEPATITIS B VIRUS IN CHRONIC LIVER DISEASE [PDF]

, 2014
Introduction: Hepatitis B is one of the most frequent etiological factors for chronic liver diseases worldwide. Recent studies have suggested the important role of the genetic diversity of the virus on natural course of hepatitis B. Hepatitis B e-antigen
Chaloska Ivanova Viktorija, Curakova Elena, Genadieva Dimitrova Magdalena, Koloska Valentina, Todorovska Beti   +4 more
core   +2 more sources

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, EarlyView.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source