Results 121 to 130 of about 13,643,530 (312)

Real-time PCR quantitation of hepatitis B virus DNA using automated sample preparation and murine cytomegalovirus internal control [PDF]

, 2005
Quantitation of circulating hepatitis B virus (HBV) DNA is important for monitoring disease progression and for assessing the response to antiviral therapy. Several commercial and 'in house' assays for HBV DNA quantitation have been described but many of
Tedder, RS, Ayliffe, U, Grant, PR, Ferns, RB, Garson, JA   +4 more
core  

Transformer‐Based Multitask Framework Integrating Habitat and Deep Learning for Predicting Early Disease Control and Survival in Immunotherapy‐Treated Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study developed ECOS‐Net, a transformer‐based multitask framework integrating CT‐derived habitat and 2.5D deep learning features to simultaneously predict early disease control and overall survival in hepatocellular carcinoma patients treated with immune checkpoint inhibitors.
Xiaona Fu, Yusheng Guo, Bingxin Gong, Jie Lou, Ning Wang, Xuejun Chen, Hongtao Hu, Rundong Wang, Xiaofang Guo, Shanmei Li, Yangyang Xie, Shichao Long, Mengsi Li, Shubo Pan, Wen Shen, Zhaogang Zhang, Zifang Song, Pengchen Liang, Xiaoyun Liang, Peng Sun, Guilin Zhang, Shanshan Jiang, Jinxiang Zhang, Lian Yang   +23 more
wiley   +1 more source

Incidence of Hepatitis B and HIV Virus at Cadaver of IV Drug Abusers in Tehran [PDF]

Injection drug use has been the most growing rout of drug abuse in Iran in the past decade and it has been responsible for the transmission of HIV virus in more than two third of cases.
اخلاقی, میترا, توفیقی زواره, حسن, قربانی, مظاهر, مصطفی زاده, بابک, محقق, علیرضا, یغمائی, اسدلله, فرزانه, اسماعیل   +6 more
core  

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

Angewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma, Komal Sharma, Anku Sharma, Kamya Rao, Rahul Jain, Brett VanVeller   +5 more
wiley   +2 more sources

The overlapping coinfection of hepatitis B virus and anti-hepatitis C virus antibody in tuberculosis patients: Unraveling co-infection patterns and clinical implications

SAGE Open Medicine
Aims: Viral hepatitis and tuberculosis are major public health concerns with shared risk factors, especially in marginalized communities. Despite this, routine hepatitis B and C viruses screening in tuberculosis patients is uncommon.
Malihe Naderi, Seyed Masoud Hosseini, Seyed Amir Soltani, Vahideh Hamidi Sofiani, Abdolvahab Moradi   +4 more
doaj   +1 more source

Hepatitis B Virus and Hepatitis C Virus Co-infection: An Evaluation of Eighty-Two Patients

Viral Hepatitis Journal, 2017
Objective: In this study, we aimed to investigate the characteristics and treatment results of 82 co-infected patients with hepatitis B virus (HBV)/hepatitis C virus (HCV).Materials and Methods: Four university hospitals evaluated HBV/HCV co-infection ...
Bilgehan AYGEN, Özgür GÜNAL, Orhan YILDIZ, Mustafa Kemal ÇELEN, Sila AKHAN, Sener BARUT, Celal AYAZ   +6 more
doaj   +1 more source

USP4‐Dependent CHAF1B Stabilization Regulates Distinct SETDB1 Ubiquitin States Linked to AKT T308 Signaling and Lipogenic Remodeling in HCC

Advanced Science, EarlyView.
USP4 stabilizes CHAF1B by limiting K48‐linked ubiquitination. Stabilized CHAF1B supports UHRF1‐associated K63‐linked SETDB1 ubiquitination and cytoplasmic redistribution, whereas CHAF1B loss favors VHL‐dependent K11‐associated degradative ubiquitination and proteasomal loss of SETDB1.
Saiyan Bian, Yun Tong, Wenkai Ni, Zhangzhi Tang, Weiting Chen, Kexin Ma, Lihan Jiang, Jiayu Shao, Xuyang He, Wenjie Zheng   +9 more
wiley   +1 more source

NAFLD‐related hepatocellular carcinoma: The growing challenge

Hepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison   +2 more
wiley   +1 more source

Factors associated with testing for hepatitis C in an internet-recruited sample of men who have sex with men.

, 2001
BACKGROUND: Nearly 4 million individuals in the United States (1.8%) have been infected with hepatitis C virus, yet few are aware of their infection. GOAL: To identify correlates associated with hepatitis C virus testing among a sample of men who have ...
Diclemente, RJ, Hergenrather, KC, Rhodes, SD, Yee, LJ, KENNETH C. HERGENRATHER, SCOTT D. RHODES, LELAND J. YEE, RALPH J. DICLEMENTE   +7 more
core   +1 more source

An Adenoviral‐Vectored Tp0326 Vaccine Elicits Robust Functional Antibodies to Prevent Treponema pallidum Dissemination in a Rabbit Model

Advanced Science, EarlyView.
Vaccination promotes cellular infiltration into primary lesions and effectively inhibits T. pallidum dissemination to distal organs. Notably, transfer of lesion tissue from immunized animals fails to establish infection in naive recipients, confirming specific protective immunity.
Yinbo Jiang, Xinyuan Li, Lixia Huang, Xiangcai Zhang, Wujian Ke   +4 more
wiley   +1 more source