Harnessing Nanohybridized Niclosamide for Precision Mpox Therapeutics
This study investigates the potential of nanohybridized niclosamide as a therapeutic agent for Mpox, focusing on enhanced bioavailability, improved antiviral efficacy, and controlled drug release achieved through nanoengineering. The research emphasizes significant advancements in formulation strategies, mechanistic insights, and therapeutic outcomes ...
N. Sanoj Rejinold+2 more
wiley +1 more source
DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding+5 more
wiley +1 more source
Maternal pre-pregnancy infection with hepatitis B virus and the risk of preterm birth: a population-based cohort study [PDF]
Background Preterm birth is the leading cause of child death in children younger than 5 years. Large cohort studies in developed countries have shown that maternal hepatitis B virus infection is associated with preterm birth, but there is little ...
Liu, Jue+5 more
core +1 more source
Specific and Nonhepatotoxic Degradation of Nuclear Hepatitis B Virus cccDNA
Clearance of Chronic Virus The family of mRNA-editing enzymes, APOBEC, restricts hepatitis B virus (HBV) replication. Lucifora et al. (p. 1221, published online 20 February; see the Perspective by Shlomai and Rice) provide evidence that specific APOBECs ...
J. Lucifora+23 more
semanticscholar +1 more source
Modeling the dynamics of the Hepatitis B virus via a variable-order discrete system [PDF]
We investigate the dynamics of the hepatitis B virus by integrating variable-order calculus and discrete analysis. Specifically, we utilize the Caputo variable-order difference operator in this study. To establish the existence and uniqueness results of the model, we employ a fixed-point technique.
arxiv +1 more source
General Epidemiological Parameters of Viral Hepatitis A, B, C, and E in Six Regions of China: A Cross-Sectional Study in 2007 [PDF]
BACKGROUND: Viral hepatitis is a serious health burden worldwide. To date, few reports have addressed the prevalence of hepatitis A, B, C, and E in China. Therefore, the general epidemiological parameters of viral hepatitis remain unknown.
Bi, Shengli+10 more
core +3 more sources
Universal Prophylactic Antitumor Vaccination Using Stem Cell Membrane‐Coated Nanoparticles
Induced pluripotent stem cell membrane is coated onto adjuvant‐loaded nanoparticle cores to create a universal cancer vaccine. The formulation utilizes oncofetal antigens present on the cell membrane to elicit broadly protective immune responses in vivo.
Nishta Krishnan+10 more
wiley +1 more source
Re-cycling of DNA-containing Capsids Enhances Hepatitis B Virus Infection [PDF]
Hepatitis B virus infection is a deadly liver disease. A part of newly produced HBV DNA-containing capsids are reused as a core particle in HBV replication. It is investigated that the recycling of HBV capsids greatly affects the intracellular dynamics of HBV infection.
arxiv
Hepatitis B Virus Screening and Vaccination [PDF]
Hepatitis B is a virus that mostly affects the liver, it could be asymptomatic and if left untreated or undetected, could lead to liver cancer, cirrhosis or even death. When Hepatitis B virus enters the body, it could be detected as early as 30 days post
Umeh, Uwaezu J
core +1 more source
Orthotopic liver transplantation for patients with hepatitis B virus–related liver disease [PDF]
Fifty‐nine patients with prior hepatitis B virus infection underwent orthotopic liver transplantation. During the first 2 mo, mortality was not significantly different in the hepatitis B virus–infected group (25.5%) vs. a hepatitis B virus–immune control
Corman+19 more
core +1 more source