Results 211 to 220 of about 14,611,152 (262)

Virological and pathological characterization of an outbreak of domestic cat hepatitis B virus infection in a cat shelter in Japan. [PDF]

J Vet Med Sci
Kato NX, Dosaka H, Adachi Y, Kaneko Y, Hirai T, Sekiguchi S, Fuke N, Saito A.   +7 more
europepmc   +1 more source

Tofacitinib Regulates β‐Catenin Nuclear Translocation to Inhibit FLS Migration and Alleviate Clinical Symptoms of RA

iNew Medicine, EarlyView.
ABSTRACT Objective Tofacitinib is a Janus kinase (JAK) inhibitor approved for the treatment of moderate‐to‐severe rheumatoid arthritis (RA). However, its synovium‐related molecular mechanisms, particularly its regulatory effect on fibroblast‐like synoviocyte (FLS) migration, remain incompletely understood.
Shuqi Fang, Tianjing Zhang, Ling Hu, Ruijin Liu, Leyi Jia, Menglin Bai, Jiale Dong, Yuchen Zhao, Han Wang, Lei Zhang, Tao Li, Youcai Deng, Xianzheng Zhang, Lingling Zhang   +13 more
wiley   +1 more source

An umbrella review navigating the nationwide burden of hepatitis B virus infection in Ethiopia: A call for action on vaccination, safe blood, and infection prevention. [PDF]

PLoS One
Demeke AD, Tsegaye A, Bayable A, Tamir T, Mekuriaw BY, Gebremeskele BT, Demeke A, Abebe M, Gessesse AD, Yehualashet DE, Gebrie H, Amede ES.   +11 more
europepmc   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

National Prevalence and Risk Factors of Hepatitis B Virus Infection in Tunisia Two Decades After Vaccine Introduction. [PDF]

Vaccines (Basel)
Fourati A, Ben Hadj M, Dhaouadi S, Hechaichi A, Letaief H, Safer M, Cherif A, Saffar F, Chelly S, Bouguerra H, Bahrini A, Talmoudi K, Chouki T, Hazgui O, Hannachi N, Bahri O, Bouafif É P Ben Alaya N.   +16 more
europepmc   +1 more source

Development of a Machine Learning Algorithm for Differential Diagnosis Between Primary Immune Thrombocytopenia and Connective Tissue Disease‐Related Thrombocytopenia in Pediatric Patients

Journal of Clinical Laboratory Analysis, EarlyView.
Primary immune thrombocytopenia (ITP) and connective tissue disease‐related thrombocytopenia (CTD‐TP) share overlapping initial presentations in children, often leading to delayed diagnosis and suboptimal management. While existing literature focuses on therapeutic strategies, this study is the first to develop a machine learning (ML)‐based diagnostic ...
Furong Kang, Mei Yan, Yingbin Yue, Xuemei Wang, Yu Liu   +4 more
wiley   +1 more source

Accuracy of Diagnostic Investigations in Monitoring Hepatitis B Virus Infection: Strengths, Limitations, and Emerging Biomarkers. [PDF]

Int J Mol Sci
Bozomitu LI, Lupu A, Lupu VV, Gimiga N, Anton Paduraru DT, Mîndru DE, Mihai M, Anton C, Anton E, Mitrea M, Adam-Raileanu A, Forna L.   +11 more
europepmc   +1 more source

Association of IFN‐γ +874 T/A Polymorphism With COVID‐19 Susceptibility, Severity, and Inflammatory Response: A Case–Control Study From Southern Iran

Journal of Clinical Laboratory Analysis, EarlyView.
Graphical abstract illustrating the association between IFN‐γ +874 T/A polymorphism and COVID‐19 outcomes. TA and AA genotypes are linked to increased susceptibility, higher inflammatory markers (notably IL‐6), greater disease severity, and longer hospitalization.
Nasir Arefinia, Bahman Aghcheli, Seyed Mohammad Ali Hashemi, Zohreh‐al‐sadat Ghoreshi, Emad Behboudi   +4 more
wiley   +1 more source

Characteristics and immune dynamics of peripheral blood immune cells and cytokines in individuals with chronic hepatitis B virus infection. [PDF]

Sci Rep
Xiao L, Dong Z, He Y, Fan J, Duan H, Jiang X, Wei C, Ma T, Zhang Y.   +8 more
europepmc   +1 more source

Rapid maternal death surveillance and response during a hepatitis E virus outbreak in Madani, Al Jazera state, Sudan

International Journal of Gynecology &Obstetrics, EarlyView.
Mawda Alshaarany, Benjamin Black, Gillian Burkhadt, Noor Rijnberg, Abrar Abdelsalam Zakria Sharif, Maura Daly, Gautam Harigovind, Ali Almohammed   +7 more
wiley   +1 more source