This study integrates scRNA‐seq, multiplex immunofluorescence, and clinical data to identify HLA‐DR⁺tumor cells uniquely enriched in Hepatocellular carcinoma (HCC) with hepatitis B virus (HBV). These cells express MHC II, associate with PD‐L1, recruit and exhaust CD8⁺T cells, predict poor survival, and serve as potential biomarkers for immunotherapy ...
Jun‐Qing Chang+17 more
wiley +1 more source
EPIDEMIOLOGICAL CHARACTERISTICS OF CHRONIC VIRAL HEPATITIS IN THE RUSSIAN FEDERATION IN 1999–2009
. The information concerning incidence, prevalence and morbidity of chronic viral hepatitis (CVH) in the territories of the Russian Federation for the period 1999–2009 is presented in the analytical review.
S. L. Mukomolov, I. A. Levakova
doaj +1 more source
COVID-19 Mid-term Impact on Hepatocellular Carcinoma in Patients With Hepatitis C Chronic Infection. [PDF]
Guler-Margaritis S+11 more
europepmc +1 more source
Factors associated with spontaneous clearance of chronic hepatitis C virus infection [PDF]
Background & Aims: Spontaneous clearance of chronic hepatitis C virus (HCV) infection (CHC) is rare. We conducted a retrospective case-control study to identify rates and factors associated with spontaneous clearance of CHC.
Aitken, Celia+11 more
core +2 more sources
Magnetite Micro/Nanorobots for Efficient Targeted Alleviation of Inflammatory Bowel Disease
Improved reactive oxygen species scavenging capacities of functionalized micro/nanorobots (MNRs) are useful for the treatment of inflammatory bowel disease (IBD). MNRs can break the harmful bacteria in IBD, thereby eliminating inflammation and restoring the intestinal barrier function.
Ying Feng+5 more
wiley +1 more source
Prevalence and Pattern of Resistance in NS5A/NS5B in Hepatitis C Chronic Patients Genotype 3 Examined at a Public Health Laboratory in the State of São Paulo, Brazil. [PDF]
de Torres Santos AP+9 more
europepmc +1 more source
Vitamin D as One of Predicators of the Stable Viral Response to Antiviral Therapy in Patients with Chronis Hepatitis С [PDF]
Chronic hepatitis C (CHC) it is not exceptionally medical problem but a significant social and economic threat, taking into account the unfavorable consequences of this disease: cirrhosis and hepatocellular carcinoma.
Androsova, O. (Olga)+3 more
core
Dynamics of cell population structure in liver biopsy of the patients with chronic hepatitis viral infection [PDF]
The cell population analysis of liver biopsies from the patients with both chronic hepatitis, chronic viral hepatitis C (HCV) and chronic viral hepatitis B (HBV) included the comparative evaluation of the specific part of non-parenchymal elements ...
Filimonova, Galina+3 more
core +3 more sources
TMCO3 as a downstream target of ALKBH5 is found, which regulates its expression in an m6A‐dependent manner, and then a new phosphorylation site on TMCO3 is identified and determines the specific mechanism of TMCO3 with AKT. Moreover, the combined treatment of targeting the TMCO3 and inhibition of AKT in mice models with HCC achieves great results ...
Xinxin Li+8 more
wiley +1 more source
КЛИНИКО-ЛАБОРАТОРНАЯ ХАРАКТЕРИСТИКА ХРОНИЧЕСКИХ ГЕПАТИТОВ И ЦИРРОЗОВ ПЕЧЕНИ РАЗЛИЧНОЙ ЭТИОЛОГИИ
The review of literature discusses the clinical and biochemical changes in patients with chronic hepatitis C, chronic hepatitis of alcoholic etiology, chronic hepatitis combined genesis (HCV + alcohol) and cirrhosis in the outcome of hepatitis, liver ...
А. Р. Билалова+1 more
doaj +1 more source