Results 131 to 140 of about 1,321,964 (375)
Mathematical Model and Analysis of Transmission Dynamics of Hepatitis B Virus [PDF]
arXiv, 2017 Hepatitis B is a potentially life-threatening liver infection caused by the hepatitis B virus (HBV). In this paper, the transmission dynamics of hepatitis B is formulated with a mathematical model with considerations of different classes of individuals, namely immunized, susceptible, latent,infected and recovered class.
arxiv
Advanced Science, EarlyView.Macrophage GHSR‐Foxo1 axis regulates CCl4‐induced liver fibrosis by promoting inflammation and TGF‐β1‐mediated HSC activation. GHSR activates PKA‐dependent phosphorylation of Foxo1 at serine 273, promoting macrophage pro‐inflammatory polarization to enhance the production of pro‐inflammatory cytokines that damage hepatocytes, thereby inducing liver ...
Da Mi Kim +9 more
wiley +1 more source
Perturbation of a globally stable equilibrium: application on an age-structured model [PDF]
arXiv, 2015 In this manuscript we consider an age structured epidemic system modelling the dynamics of transmission of immunizing disease like Hepatitis B virus. Our model takes into account age as well as two classes of infected individuals (chronic carriers and acute infected human).
arxiv
Health-Related Quality of Life in Portuguese Patients with Chronic Hepatitis C [PDF]
, 2016 INTRODUCTION: Chronic hepatitis C virus (HCV) infection impacts multiple health and psychosocial dimensions and encompasses a significant overall burden as it progresses to advanced stages of hepatic disease.
Pedroto, I., Rei, A., Rocha, M.
core +1 more source
The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
Advanced Science, EarlyView.This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen +6 more
wiley +1 more source
Asthenia in Children with Chronic Viral Hepatitis
Zdorovʹe Rebenka, 2015 In the article results of own researches concerning peculiarities of the course of asthenic syndrome in school-aged children with chronic hepatitis B, C and mixed forms are provided. It is established that chronic hepatitis C as well as a mixed hepatitis
I.S. Lembryk
doaj +1 more source
Non cell autonomous upregulation of CDKN2 transcription linked to progression of chronic hepatitis C disease [PDF]
, 2013 Chronic hepatitis C virus infection (C-HC) is associated with higher mortality arising from hepatic and extrahepatic disease. This may be due to accelerated biological aging; however, studies in C-HC have thus far been based solely on telomere length as ...
Barclay, Stephen +7 more
core +2 more sources
CXCL13 Expression Promotes CAR T Cell Antitumor Activity and Potentiates Response to PD‐1 Blockade
Advanced Science, EarlyView.This study demonstrates that engineering CAR T cells to express CXCL13 enhances their antitumor efficacy and significantly improves responsiveness to PD‐1 immune checkpoint blockade. CXCL13 promotes T cell persistence, and resistance to early exhaustion via the AKT‐mTOR pathway.
Yang Zhou +15 more
wiley +1 more source
Aktualʹnaâ Infektologiâ, 2014 The use of combination antiviral therapy enables to achieve sustained virologic response in patients with chronic hepatitis C, but in some patients side effects occur during treatment.
D.V. Dontsov +7 more
doaj +1 more source
Renal function changes in chronic hepatitis B patients [PDF]
arXivThe best way to treat chronic hepatitis B is with pegylated interferon alone or with oral antiviral drugs. There is limited research comparing the renal safety of entecavir and tenofovir when used with pegylated interferon. This study will compare changes in renal function in chronic hepatitis B patients treated with pegylated interferon and either ...
arxiv