Results 161 to 170 of about 1,321,964 (375)
Combination Therapy for Chronic Hepatitis B Using Capsid Recycling Inhibitor [PDF]
arXivIn this paper, we investigate the dynamics of hepatitis B virus infection taking into account the implementation of combination therapy through mathematical modeling. This model is established considering the interplay between uninfected cells, infected cells, capsids, and viruses. Three drugs are considered for specific roles (i) pegylated interferon (
arxiv
Modeling the dynamics of Hepatitis C Virus with combined antiviral drug therapy: Interferon and Ribavirin [PDF]
arXiv, 2011 A mathematical modeling of Hepatitis C Virus (HCV) dynamics has been presented in this paper. The proposed model, which involves four coupled ordinary differential equations, describes the interaction of target cells (hepatocytes), infected cells, infectious virions and non-infectious virions.
arxiv
Australian Journal of Social Issues, EarlyView.ABSTRACT Hearing loss is a poignant issue in many Aboriginal and Torres Strait Islander communities and, without sufficient support, it can also contribute to disabling life experiences. The National Disability Insurance Scheme (NDIS) is intended to provide support to eligible people experiencing disability, however, to effectively serve this ...
Hannah Lack +4 more
wiley +1 more source
Model Based Framework for Estimating Mutation Rate of Hepatitis C Virus in Egypt [PDF]
arXiv, 2013 Hepatitis C virus (HCV) is a widely spread disease all over the world. HCV has very high mutation rate that makes it resistant to antibodies. Modeling HCV to identify the virus mutation process is essential to its detection and predicting its evolution.
arxiv
, 2012 American Indian/Alaska Natives (AI/AN) patients at an urban residential chemical dependency treatment center participated in a viral hepatitis prevention project.
Brucker, Rachel +8 more
core
Australian Journal of Social Issues, EarlyView.ABSTRACT This qualitative study aimed to understand how migration experiences shape wellbeing and quality of life (QoL) for Asian‐born men who have sex with men (MSM) who are living with HIV in Australia, and to identify relevant support needs. Drawing from intersectionality theory, this paper reports findings from semi‐structured interviews with Asian‐
Thomas Norman +9 more
wiley +1 more source
Understanding Hepatitis B Virus Infection through Hepatocyte Proliferation and Capsid Recycling [PDF]
arXivProliferation of uninfected as well as infected hepatocytes and recycling of DNA-containing capsids are two major mechanisms playing significant roles in the clearance of hepatitis B virus (HBV) infection. In this study, the temporal dynamics of this infection are investigated through two in silico bio-mathematical models considering both ...
arxiv
Influence of Intracellular Delay on the Dynamics of Hepatitis C Virus [PDF]
arXiv, 2014 In this paper we present a delay induced model for hepatitis C virus incorporating the healthy and infected hepatocytes as well as infectious and noninfectious virions. The model is mathematically analyzed and characterized, both for the steady states and the dynamical behavior of the model.
arxiv
Application of humanized mice in the safety experiments of antibody drugs
Animal Models and Experimental Medicine, EarlyView.The graphical abstract of this review highlights the critical role of humanized mice in the safety evaluation of antibody drugs. First, the inherent immunogenicity of antibody drugs can lead to the production of antidrug antibodies and hypersensitivity reactions on repeated administration.
Zhimin Sun +9 more
wiley +1 more source
Journal of Global Antimicrobial ResistanceOBJECTIVE: This study aims to investigate the Hepatitis C Virus (HCV) genotypes, changes in genotype distribution, and the effects of migration among chronic hepatitis C patients who presented at a university hospital in Diyarbakır over a decade ...
Esra Yenihal +3 more
doaj