Results 11 to 20 of about 20,388,994 (310)

Clinical and epidemiological characteristic of chronic hepatitis C in the republic of Tyva

open access: yesЖурнал инфектологии, 2023
Aim: To assess the current epidemiological situation and establish the dominant clinical profile of patients with chronic hepatitis C, taking into account the stage of the disease and the molecular genetic characteristics of the virus in the Republic of ...
A. A. Saryglar   +4 more
doaj   +1 more source

Management of chronic hepatitis C [PDF]

open access: yesPostgraduate Medical Journal, 2005
AbstractHepatitis C virus (HCV) infection is transmitted primarily through percutaneous exposure to blood, and most infections are associated with injection drug use. Progression to chronic HCV occurs in 55% to 86% of infected people, and persistent infection is a major cause of cirrhosis, end stage liver disease, and hepatocellular carcinoma.
V, Lo Re, J R, Kostman
openaire   +2 more sources

A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C [PDF]

open access: yes, 2012
Background: To perform a comprehensive study on the relationship between vitamin D metabolism and the response to interferon-α-based therapy of chronic hepatitis C.
Jörg Bojunga   +66 more
core   +2 more sources

Tracking Virus-Specific CD4+ T Cells during and after Acute Hepatitis C Virus Infection [PDF]

open access: yes, 2007
Background. CD4+ T cell help is critical in maintaining antiviral immune responses and such help has been shown to be sustained in acute resolving hepatitis C.
Paul Klenerman   +175 more
core   +2 more sources

Chronic Hepatitis C in the Pandemic

open access: yesKlimik Dergisi/Klimik Journal, 2021
Corona virus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, affected all the world and has been a major cause for significant morbidity and mortality. COVID-19 represents with pulmonary manifestations, but in more than half of the cases, other organs, especially hepatic involvement, are observed ...
Süda Tekin   +3 more
openaire   +3 more sources

Soluble serum CD81 is elevated in patients with chronic hepatitis C and correlates with alanine aminotransferase serum activity [PDF]

open access: yes, 2012
Aim: Cellular CD81 is a well characterized hepatitis C virus (HCV) entry factor, while the relevance of soluble exosomal CD81 in HCV pathogenesis is poorly defined.
Kronenberger Bernd   +26 more
core   +2 more sources

Lipoprotein Receptors and Lipid Enzymes in Hepatitis C Virus Entry and Early Steps of Infection

open access: yesScientifica, 2012
Viruses are obligate intracellular agents that depend on host cells for successful propagation, hijacking cellular machineries to their own profit. The molecular interplay between host factors and invading viruses is a continuous coevolutionary process ...
Eve-Isabelle Pécheur
doaj   +1 more source

Prevalence of hepatitis C virus infection in patients with cardiomyopathy

open access: yesAnnals of Hepatology, 2009
Chronic hepatitis C can be associated with extrahepatic manifestations; thus, we explored the association of this viral infection with dilated cardiomyopathy in a group of sixty-three patients with a cardiac ejection fraction of less than 40% determined ...
Vijaya Boyella;   +5 more
doaj   +1 more source

Response to combination therapy with interferon alfa-2a and ribavirin in chronic hepatitis C according to a TNF-alpha promoter polymorphism [PDF]

open access: yes, 2003
Background. Tumor necrosis factor-alpha (TNF-alpha) is involved in the pathogenesis of chronic active hepatitis C. Polymorphisms in the promoter region of the TNF-alpha gene can alter the TNF-alpha expression and modify the host immune response.
Konig, A.   +8 more
core   +1 more source

Genetic analyses reveal a role for vitamin D insufficiency in HCV-associated hepatocellular carcinoma development [PDF]

open access: yes, 2013
Background: Vitamin D insufficiency has been associated with the occurrence of various types of cancer, but causal relationships remain elusive. We therefore aimed to determine the relationship between genetic determinants of vitamin D serum levels and ...
Jörg Bojunga   +127 more
core   +3 more sources

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