Results 191 to 200 of about 1,321,964 (375)
Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu+11 more
wiley +1 more source
MRI quantification of liver fibrosis using diamagnetic susceptibility: An ex-vivo feasibility study [PDF]
In chronic liver disease, liver fibrosis develops as excessive deposition of extracellular matrix macromolecules, predominantly collagens, progressively form fibrous scars that disrupt the hepatic architecture, and fibrosis, iron, and fat are interrelated.
arxiv
Hepatitis C and ageing: a community brief [PDF]
Executive summary: An estimated 226,700 people in Australia are living with chronic hepatitis C. While the numbers of people estimated to have been infected with hepatitis C has reduced over the past 15 years, the number of people with hepatitis C ...
Jack Wallace, Jacqui Richmond
core
Liver pathology in rural south-west Cameroon [PDF]
In a prospective study, 102 hospital patients with liver disease were evaluated in West Cameroon, Africa. Blood donors, pregnant women and patients without liver disease served as controls.
Bianchi, L.+3 more
core
Cp*Co(III)‐catalyzed C–H functionalization of bioactive heterocyclic motifs
Directed carbon–hydrogen bond functionalization of biologically active scaffolds is attractive as it enables the selective modification of sophisticated structures, enhancing the efficiency of drug development by adopting diverse functional groups. This review summarizes recent advances in cobalt‐catalyzed C–H functionalizations of bioactive motifs ...
Yeongmi Park+3 more
wiley +1 more source
NAFLD‐related hepatocellular carcinoma: The growing challenge
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah+2 more
wiley +1 more source
Recent advances of nanomaterials in imaging liver fibrosis
Schematic summary on the latest strategies of liver fibrosis imaging based on various nanomaterials. Abstract Liver fibrosis is a pathological process resulting from prolonged exposure to various injury factors. It is characterized by the abnormal proliferation and activation of hepatic stellate cells and excessive deposition of extracellular matrix ...
Jin Cui+11 more
wiley +1 more source
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou+13 more
wiley +1 more source
Autoimmune and neoplastic thyroid diseases associated with hepatitis C chronic infection. [PDF]
Fallahi P+5 more
europepmc +1 more source