Results 271 to 280 of about 20,261,505 (305)

Selective [9‐15N] Guanosine for NMR Studies of Large RNAs

ChemBioChem, Accepted Article.
RNAs regulate various cellular processes using malleable 3D structures, and understanding the factors that control RNA structure and dynamics is critical for understanding their mechanisms of action. To mitigate factors that have limited studies of large, functionally relevant RNAs by solution NMR spectroscopy, we have extended a recently described 2H ...
Solomon K. Attionu, Rita Dill, Michael F. Summers, David A. Case, Jan Marchant, Theodore Kwaku Dayie   +5 more
wiley   +1 more source

Engineering of small ribozymes acting on RNA: What is needed to make a new function work with an existing catalyst?

ChemBioChem, Accepted Article.
The engineering of nucleic acids has been a longstanding objective in research, with the field gaining significant attention following the discovery of ribozymes in the early 1980s. Numerous nucleic acid catalysts have been developed to catalyze a wide range of reactions, and the structures of ribozymes have been modified to allow allosteric regulation
Sabine Müller, Constanze Ebermann
wiley   +1 more source

Development and Initial Use of a New Inflammatory Bowel Disease Clinical Database Integrating Both Eastern and Western Clinical Characteristics

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Background The increasing incidence of inflammatory bowel disease (IBD) presents significant medical and societal challenges. A well‐designed IBD database is crucial for both epidemiological studies and clinical management. However, inconsistencies between regional databases hinder cross‐institutional and international research, especially ...
Jingshuang Yan, Rongrong Ren, Ruqi Chang, Wanyue Dan, Xiaohan Zhang, Fei Pan, Bin Yan, Hongzhe Lee, Ni Josie, Gang Sun, Lihua Peng, Gary D. Wu, Yunsheng Yang   +12 more
wiley   +1 more source

Harnessing Viral Proteases for Cellular and Molecular Engineering

Chemistry–Methods, EarlyView.
Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui, Tien‐Hung Lan, Yubin Zhou   +2 more
wiley   +1 more source

Epidemiology of hepatitis C in central Portugal. Prevalence of anti-HCV in the population of the Coimbra District.

, 1994
Alexandra F. Santos, Armando Carvalho, Daniela Bento, R Sá, J. Tomaz, Vítor Rodrigues, L Pais, Aurélia F. Porto   +7 more
openalex   +1 more source

Virological techniques for the diagnosis and monitoring of hepatitis B and C

Annals of Hepatology, 2009
Stéphane Chevaliez, Jean-Michel Pawlotsky, Prof., MD, PhD   +1 more
doaj  

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National treatment programme of hepatitis C in Egypt: Hepatitis C virus model of care

Journal of Viral Hepatitis, 2017
Mohamed El-kassas, Imam Waked
exaly   +2 more sources

Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose.

Annals of Internal Medicine, 2004
BACKGROUND Treatment with pegylated interferon (peginterferon) and ribavirin for 48 weeks is more effective than conventional interferon and ribavirin in patients with chronic hepatitis C.
S. Hadziyannis, H. Sette, T. Morgan, V. Balan, M. Diago, P. Marcellin, G. Ramadori, H. Bodenheimer, D. Bernstein, M. Rizzetto, S. Zeuzem, P. Pockros, A. Lin, A. Ackrill   +13 more
semanticscholar   +1 more source

Binding of hepatitis C virus to CD81.

Science, 1998
Chronic hepatitis C virus (HCV) infection occurs in about 3 percent of the world's population and is a major cause of liver disease. HCV infection is also associated with cryoglobulinemia, a B lymphocyte proliferative disorder.
P. Pileri, Y. Uematsu, S. Campagnoli, G. Galli, F. Falugi, R. Petracca, A. Weiner, M. Houghton, D. Rosa, G. Grandi, S. Abrignani   +10 more
semanticscholar   +1 more source

Global epidemiology of hepatitis C virus infection.

Lancet. Infectious Diseases (Print), 2005
C. Shepard, L. Finelli, M. Alter
semanticscholar   +1 more source