Results 21 to 30 of about 477,291 (156)

Association of TM6SF2 rs58542926 T/C gene polymorphism with hepatocellular carcinoma: a meta-analysis

BMC Cancer, 2019
Background Hepatocellular carcinoma (HCC) is the sixth-most common malignancy worldwide. Multiple previous studies have assessed the relationship between TM6SF2 gene polymorphism and the risk of developing HCC, with discrepant conclusions reached.
Shan Tang, Jing Zhang, Ting-Ting Mei, Hai-Qing Guo, Xin-Huan Wei, Wen-Yan Zhang, Ya-Li Liu, Shan Liang, Zuo-Peng Fan, Li-Xia Ma, Wei Lin, Yi-Rong Liu, Li-Xia Qiu, Hai-Bin Yu   +13 more
doaj   +1 more source

Prognosis and therapeutic benefits prediction based on NK cell marker genes through single-cell RNA-seq with integrated bulk RNA-seq analysis for hepatocellular carcinoma

Frontiers in Oncology, 2023
Tumor-infiltrating immune cells greatly participate in regulating tumorigenesis and metastasis of hepatocellular carcinoma (HCC). Natural killer cell, as an important role of innate immunity, plays an indispensable role in antitumor immunity and regulate
Yao Yang, Shaopin She, Liying Ren, Bigeng Zhao, Dongbo Chen, Hongsong Chen   +5 more
doaj   +1 more source

The burden of hepatitis C virus in the world, China, India, and the United States from 1990 to 2019

Frontiers in Public Health, 2023
Background and aimHepatitis C virus infection can lead to an enormous health burden worldwide. Investigating the changes in HCV-related burden between different countries could provide inferences for disease management.
Jia Yang, Jin-Lei Qi, Xiao-Xiao Wang, Xiao-He Li, Rui Jin, Bai-Yi Liu, Hui-Xin Liu, Hui-Ying Rao   +7 more
doaj   +1 more source

HBV pregenome RNA as a predictor of spontanous HBeAg seroconversion in HBeAg-positive chronic hepatitis B patients

BMC Gastroenterology, 2023
Background Previous studies have indicated that HBV pregenome RNA (HBV pgRNA) could predict HBeAg seroconversion among the chronic hapatitis B (CHB) patients treated with pegylated interferon (Peg-IFN) or nucleos(t)ide analogues (NAs).
Guangjun Song, Ruifeng Yang, Qian Jin, Juan Liu, Huiying Rao, Bo Feng, Yandi Xie   +6 more
doaj   +1 more source

Hepatitis C Virus Exploits Death Receptor 6-mediated Signaling Pathway to Facilitate Viral Propagation

Scientific Reports, 2017
The life cycle of hepatitis C virus (HCV) is highly dependent on host proteins for virus propagation. By transcriptome sequencing analysis, we identified host genes that were highly differentially expressed in HCV-infected cells.
Trang T. D. Luong, Giao V. Q. Tran, Dong-Jo Shin, Yun-Sook Lim, Soon B. Hwang   +4 more
doaj   +1 more source

Hepatitis B, C, and delta in the general population in Mayotte: hepatitis B as a major public health concern

BMC Infectious Diseases, 2022
Background Located in southwestern Indian Ocean, Mayotte is a French territory, with a very specific demographic, social and health context. To date, epidemiological data on infections by hepatitis B (HBV), C (HCV), and delta (HDV) viruses in Mayotte ...
Cécile Brouard, Fanny Parenton, Hassani Youssouf, Stéphane Chevaliez, Emmanuel Gordien, Maxime Jean, Mathias Bruyand, Sophie Vaux, Florence Lot, Marc Ruello, Unono Wa Maore group   +10 more
doaj   +1 more source

A signature based on NKG2D ligands to predict the recurrence of hepatocellular carcinoma after radical resection

Cancer Medicine, 2023
Introduction Due to the high recurrence, the HCC prognosis remains poor. Yet, the biomarkers for predicting the recurrence of high‐risk patients are currently lacking.
Dongbo Chen, Jie Gao, Liying Ren, Pu Chen, Yao Yang, Shaoping She, Yong Xie, Weijia Liao, Hongsong Chen   +8 more
doaj   +1 more source

Identification of the viral and cellular microRNA interactomes during SARS-CoV-2 infection

Cell Reports, 2023
Summary: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has had a tremendous impact worldwide. Mapping virus-host interactions is critical to understand disease progression.
Nicolas Fossat, Emma A. Lundsgaard, Rui Costa, Lizandro R. Rivera-Rangel, Louise Nielsen, Lotte S. Mikkelsen, Santseharay Ramirez, Jens Bukh, Troels K.H. Scheel   +8 more
doaj   +1 more source

Analysis of Hepatitis C Virus Particle Heterogeneity in Immunodeficient Human Liver Chimeric fah-/- MiceSummary

Cellular and Molecular Gastroenterology and Hepatology, 2017
Background & Aims: Hepatitis C virus (HCV) is a leading cause of chronic liver diseases and the most common indication for liver transplantation in the United States.
Ursula Andreo, Ype P. de Jong, Margaret A. Scull, Jing W. Xiao, Koen Vercauteren, Corrine Quirk, Michiel C. Mommersteeg, Sonia Bergaya, Arjun Menon, Edward A. Fisher, Charles M. Rice   +10 more
doaj   +1 more source

The epidemiological profile of chronic hepatitis C with advanced hepatic fibrosis regarding virus genotype in Taiwan: A nationwide study

Journal of the Formosan Medical Association, 2021
Background/Purpose: This study aims at investigating the epidemiological profile of chronic hepatitis C (CHC) regarding hepatitis C virus (HCV) genotype in Taiwan.
Grace Hui-Min Wu, Wen-Wen Yang, Chia-Ling Liu, Raoh-Fang Pwu, Rong-Nan Chien, Po-Chang Lee, Shih-Chung Chen, Ding-Shinn Chen, Sheng-Nan Lu   +8 more
doaj   +1 more source