Results 301 to 310 of about 20,131,715 (394)

Highly replicating hepatitis C virus variants emerge in immunosuppressed patients causing severe disease. [PDF]

open access: yesNat Commun
Rothhaar P   +29 more
europepmc   +1 more source

Drug Repositioning of Pegbing® for Essential Thrombocythemia: Insights from PK/PD Modeling and Extrapolation

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pegbing® (peginterferon alfa‐2b), a pegylated interferon‐alpha, is approved for the treatment of chronic hepatitis B (CHB) and C. One of its adverse effects is platelet (PLT) suppression. It is currently being repurposed for the treatment of essential thrombocythemia (ET), a rare myeloproliferative disorder characterized by abnormally elevated PLT ...
Weizhe Jian   +7 more
wiley   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff   +6 more
wiley   +1 more source

Barriers and facilitators along the Hepatitis C reinfection journey: Qualitative interview study

open access: yes
Stuart A   +7 more
europepmc   +1 more source

Determinants of hepatitis C virus treatment completion among Los Angeles County residents. [PDF]

open access: yesBMC Infect Dis
Hernandez-Tamayo C   +18 more
europepmc   +1 more source

Health and Economic Impact of Periodic Hepatitis C Virus Testing Among People Who Inject Drugs [PDF]

open access: gold
Lin Zhu   +9 more
openalex   +1 more source

Maternal Gestational Low‐Grade Inflammation and the Risk of Anorexia Nervosa in Daughters

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Prenatal exposures have been suggested to have a programming effect on neural and metabolic development, which may affect the risk of eating disorders. We investigated the association between prospectively measured maternal gestational high‐sensitivity C‐reactive protein (hs‐CRP), an established inflammatory biomarker, and subsequent
Emma Saure   +6 more
wiley   +1 more source

Decentralised Hepatitis C Management: A Simplified, Integrated Model of Care in a Primary Health Centre in Pakistan, August 2022-June 2023. [PDF]

open access: yesJ Viral Hepat
Mazzilli S   +8 more
europepmc   +1 more source

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