Results 111 to 120 of about 612,801 (299)
Arquivos de Gastroenterologia, 2015 BackgroundThe hepatitis C virus has been recognized as the leading cause of chronic liver disease in the world. Host genetic factors have been implicated in the persistence of hepatitis C virus infection. Single nucleotide polymorphisms at positions -607
Kemper Nunes dos SANTOS +4 more
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Host neutralizing responses and pathogenesis of hepatitis C virus infection. [PDF]
, 2008 International audienceThe recent development of novel model systems for the early steps of hepatitis C virus (HCV) infection has rapidly advanced our knowledge of antibody-mediated virus neutralization in patients with acute and chronic hepatitis C. This
Baumert, Thomas, +2 more
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Advanced Science, EarlyView.The TopCas platform utilizes an engineered DNA‐RNA chimeric circular crRNA to establish topology‐gated control over CRISPR‐Cas12a activity, enabling target‐triggered self‐catalytic amplification (preamplification‐free). This system seamlessly integrates highly sensitive molecular diagnostics with conditionally controlled gene editing, demonstrating ...
Shun Zhang +7 more
wiley +1 more source
Hepatology, EarlyView., 2022 Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo +14 more
wiley +1 more source
Interferons and hepatitis C virus
Swiss Medical Weekly, 2012 Interferons are not only the first line of defence against viral infections such as hepatitis C virus infections, but they also have important roles during the chronic phase of viral infections. For over 20 years now, recombinant interferon alpha has been used for the treatment of chronic hepatitis C.
openaire +4 more sources
Advanced Science, EarlyView.ABSTRACT This paper is a formal response to the comments raised by Yiquan Wang et al. and Peikai Sun et al. on our published work entitled “GLM7–A Novel Composite Glycolipid Index Derived from Routine Health Indicators for Enhanced Diagnosis and Prediction of Multimorbidity”. We address all the comments in this response.
Zhihua Wang, Suowen Xu
wiley +1 more source
Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis
Hepatology, EarlyView., 2022 EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu +16 more
wiley +1 more source
SAGE Open MedicineBackground: Hepatitis B and C viruses are major global health problems with a high mortality rate, mostly due to serious liver diseases such as liver cirrhosis, liver failure, and hepatocellular carcinoma. The objective of this study was to determine the
Solomon Tesfaye +4 more
doaj +1 more source
Bioinformatics Techniques used in Hepatitis C Virus Research
Journal of Pure and Applied Microbiology, 2017 Hepatitis C is widely spread and induces life threatening situations. Researchers from various fields have developed vaccine, but they are not that effective because of the variation in genotype of Hepatitis virus and also not much affordable.
Vikas Kaushik +2 more
doaj +1 more source
Liver pathology in rural south-west Cameroon [PDF]
, 2017 In a prospective study, 102 hospital patients with liver disease were evaluated in West Cameroon, Africa. Blood donors, pregnant women and patients without liver disease served as controls.
Bianchi, L. +3 more
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