Results 121 to 130 of about 1,173,658 (399)

Seroprevalence of hepatitis B, C, and its associated risk factors among clinically suspected patients attending poly and Maraki Health Centers, Gondar City, North West Ethiopia

SAGE Open Medicine
Background: Hepatitis B and C viruses are major global health problems with a high mortality rate, mostly due to serious liver diseases such as liver cirrhosis, liver failure, and hepatocellular carcinoma. The objective of this study was to determine the
Solomon Tesfaye, Adefework Alemu, Endalkachew Bizualem, Daniel Mehabie, Amir Alelign   +4 more
doaj   +1 more source

ANALYSIS OF POLYMORPHISMS IN THE INTERLEUKIN 18 GENE PROMOTOR (-137 G/C AND -607 C/A) IN PATIENTS INFECTED WITH HEPATITIS C VIRUS FROM THE BRAZILIAN AMAZON

Arquivos de Gastroenterologia, 2015
BackgroundThe hepatitis C virus has been recognized as the leading cause of chronic liver disease in the world. Host genetic factors have been implicated in the persistence of hepatitis C virus infection. Single nucleotide polymorphisms at positions -607
Kemper Nunes dos SANTOS, Marcella Kelly Costa de ALMEIDA, Amanda Alves FECURY, Carlos Araújo da COSTA, Luísa Caricio MARTINS   +4 more
doaj   +1 more source

Hepatitis C virus infection [PDF]

, 2014
Hepatitis C virus (HCV) often causes persistent infection, and is an important factor in the etiology of fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). There are no preventive or therapeutic vaccines available against HCV.
Kwon, Young-Chan, Ray, Ranjit, Ray, Ratna B.   +2 more
core  

Virus de l'hépatite C et gouttelettes lipidiques [PDF]

, 2007
Hepatitis C virus and lipid ...
Hourioux, Christophe, Roingeard, Philippe   +1 more
core   +2 more sources

Risk of Late Relapse or Reinfection With Hepatitis C Virus After Achieving a Sustained Virological Response: A Systematic Review and Meta-analysis

Clinical Infectious Diseases, 2016
Sustained virological response is durable in patients treated for hepatitis C virus. Recurrence rates are generally low but increase in patient populations with risk factors for reinfection.
Bryony Simmons, J. Saleem, A. Hill, R. Riley, G. Cooke   +4 more
semanticscholar   +1 more source

Polysaccharide Adjuvants as Innate Immune Trainers: Bridging Pattern Recognition Receptor (PRR) Activation and Metabolic Reprogramming for Synthetic Vaccine Design

Advanced Science, EarlyView.
Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon, May Thazin Phoo, Yubin Kim, Jinsung Ahn, April Kim, Jutaek Nam, Soo‐Hong Lee, James J. Moon, Sejin Son   +8 more
wiley   +1 more source

Prevalence and associated factors of Hepatitis C virus and human immunodeficiency virus infections among voluntary counseling and testing clients attending private health facilities in Bahir Dar city, North West Ethiopia 2014

BMC Research Notes, 2019
Objective Although incredible progress has been made in treatment and prevention of Hepatitis C virus and human immunodeficiency virus infections, the epidemic continues to spread in developing nations.
Zena Ameha, Senait Tadesse, Abate Assefa, Belay Tessema   +3 more
doaj   +1 more source

Hepatitis B virus and hepatitis C virus infection in healthcare workers.

World Journal of Hepatology, 2016
Approximately 3 million healthcare workers per year receive an injury with an occupational instrument, with around 2000000 exposures to hepatitis B virus (HBV) and 1000000 to hepatitis C virus (HCV).
N. Coppola, S. de Pascalis, Lorenzo Onorato, Federica Calò, C. Sagnelli, E. Sagnelli   +5 more
semanticscholar   +1 more source

Blocking Lysine Crotonylation and Aerobic Glycolysis as Targeting Strategy Against mpox Virus Replication

Advanced Science, EarlyView.
Wei et al. report that MPXV infection induces aerobic glycolysis, a process mediated by the viral protein I3 through lysine crotonylation at its K102 residue. The acetyltransferase MYST1 catalyzes the crotonylation of I3 to inhibit the ubiquitin‐mediated degradation of WDR26.
Pengjun Wei, Zongzheng Zhao, Ruoqi Xu, Qin Yan, Liangzi Jiang, Fuxiao Geng, Yang Gu, Tianjiao Wang, Jing Zhou, Xiao Li, Qin Yan, Chun Lu, Wan Li   +12 more
wiley   +1 more source

Optimizing Interferon Alfa Based Therapy for Chronic Hepatitis C [PDF]

, 2011
The hepatitis C virus was first discovered in 1989 as the major cause of chronic non-A non-B hepatitis. The hepatitis C virus is a single stranded RNA virus that belongs to the family of flaviviruses.
Roomer, R. (Robert)
core