Results 181 to 190 of about 1,173,658 (399)
Myeloid p38 activation maintains macrophage–liver crosstalk and BAT thermogenesis through IL‐12–FGF21 axis
Hepatology, EarlyView., 2022 Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract
Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...María Crespo, Ivana Nikolic, Alfonso Mora, Elena Rodríguez, Luis Leiva‐Vega, Aránzazu Pintor‐Chocano, Daniel Horrillo, Lourdes Hernández‐Cosido, Jorge L. Torres, Eva Novoa, Rubén Nogueiras, Gema Medina‐Gómez, Miguel Marcos, Magdalena Leiva, Guadalupe Sabio +14 morewiley +1 more sourceInosine Triphosphate Pyrophosphatase Dephosphorylates Ribavirin Triphosphate and Reduced Enzymatic Activity Potentiates Mutagenesis in Hepatitis C Virus [PDF]
, 2018 Kristina Nystrôm, Paulina H. Wanrooij, J. Waldenström, Ludmila Adamek, Sofia Brunet, Joanna Said, Staffan Nilsson, Megan Wind‐Rotolo, Kristoffer Hellstrand, Heléne Norder, Ka‐Wei Tang, Martin Lagging +11 moreopenalex +1 more sourceGlobal prevalence and genotype distribution of hepatitis C virus infection in 2015: a modelling study.
The Lancet Gastroenterology and Hepatology, 2017 S. Blach, S. Zeuzem, M. Manns, I. Altraif, Ann-Sofi Duberg, D. Muljono, I. Waked, S. Alavian, Mei‐Hsuan Lee, F. Negro, F. Abaalkhail, A. Abdou, Maheeba Abdulla, A. Rached, I. Aho, U. Akarca, I. Ghazzawi, S. Kaabi, Faryal Al Lawati, Khalid Al Namaani, Y. A. Serkal, Said A. Al-Busafi, Layla Al-Dabal, S. Aleman, A. Alghamdi, A. Aljumah, H. Al-Romaihi, M. Andersson, V. Arendt, P. Arkkila, A. Assiri, O. Baatarkhuu, A. Bane, Z. Ben‐Ari, C. Bergin, F. Bessone, F. Bihl, A. Bizri, M. Blachier, A. Blasco, C. Mello, P. Bruggmann, C. Brunton, F. Calinas, H. Chan, A. Chaudhry, H. Cheinquer, Chien-Jen Chen, R. Chien, M. Choi, P. Christensen, W. Chuang, V. Chulanov, L. Cisneros, M. Clausen, M. Cramp, A. Craxì, E. Croes, O. Dalgard, J. Daruich, V. Ledinghen, G. Dore, M. El-Sayed, G. Ergör, G. Esmat, C. Estes, K. Falconer, E. Farag, M. L. Ferraz, P. Ferreira, R. Flisiak, S. Fraňková, I. Gamkrelidze, E. Gane, J. García-Samaniego, A. Khan, I. Gountas, A. Goldiş, M. Gottfredsson, J. Grebely, M. Gschwantler, M. Pessoa, J. Gunter, B. Hajarizadeh, O. Hajelssedig, S. Hamid, W. Hamoudi, A. Hatzakis, S. Himatt, H. Hofer, I. Hrstic, Y. Hui, B. Hunyady, R. Idilman, W. Jafri, R. Jahis, N. Janjua, P. Jarčuška, A. Jēruma, J. Jónasson, Y. Kamel, J. Kao, S. Kaymakoğlu, D. Kershenobich, J. Khamis, Young Sik Kim, L. Kondili, Z. Koutoubi, M. Krajden, H. Krarup, M. Lai, W. Laleman, W. Lao, D. Lavanchy, P. Lázaro, H. Leleu, O. Lesi, L. A. Lesmana, Michael Li, V. Liakina, Y. Lim, B. Lukšić, A. Mahomed, M. Maimets, M. Makara, A. Malu, R. Marinho, P. Marotta, S. Mauss, M. Memon, M. Correa, N. Méndez-Sánchez, S. Merat, Ammal M. Metwally, R. Mohamed, Christophe Moreno, F. Mourad, B. Müllhaupt, K. Murphy, H. Nde, R. Njouom, D. Nonković, S. Norris, S. Obekpa, S. Oguche, S. Olafsson, M. Oltman, O. Omede, C. Omuemu, O. Opare-Sem, A. Øvrehus, S. Owusu-Ofori, T. Oyunsuren, G. Papatheodoridis, K. Pasini, K. Peltekian, R. Phillips, N. Pimenov, H. Poustchi, N. Prabdial-Sing, H. Qureshi, A. Ramji, D. Razavi-Shearer, K. Razavi-Shearer, B. Redae, H. Reesink, E. Ridruejo, S. Robbins, L. Roberts, S. Roberts, W. Rosenberg, F. Roudot-thoraval, S. Ryder, R. Safadi, O. Sagalova, R. Salupere, F. Sanai, J. Ávila, V. Saraswat, R. Sarmento-Castro, C. Sarrazin, J. Schmelzer, I. Schréter, C. Seguin-Devaux, Samir R. Shah, A. Sharara, Manik Sharma, A. Shevaldin, G. Shiha, W. Sievert, M. Sonderup, K. Souliotis, D. Speičienė, J. Sperl, P. Stärkel, R. Stauber, C. Stedman, D. Struck, T. Su, V. Sypsa, S. Tan, J. Tanaka, A. Thompson, I. Tolmane, K. Tomasiewicz, J. Valantinas, P. Damme, A. J. Meer, I. Thiel, H. Vlierberghe, A. Vince, W. Vogel, H. Wedemeyer, N. Weis, V. Wong, C. Yaghi, A. Yosry, M. Yuen, E. Yunihastuti, Aasim Yusuf, E. Zuckerman, H. Razavi +221 moresemanticscholar +1 more sourceSerum Bile Acids Are Useful Indicators of Intrahepatic Recurrence After Initial Curative Hepatectomy for Hepatocellular Carcinoma
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Aim
Bile acids accumulation in hepatocytes causes liver damage and contributes to the development of hepatocellular carcinoma. However, the association between serum bile acid levels and postoperative intrahepatic recurrence in hepatocellular carcinoma remains unclear.Tomoaki Bekki, Masahiro Ohira, Yuki Imaoka, Seiichi Simizu, Tomoyuki Abe, Shintaro Kuroda, Hiroyuki Tahara, Kentaro Ide, Tsuyoshi Kobayashi, Hideki Ohdan +9 morewiley +1 more sourceMacrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis
Hepatology, EarlyView., 2022 EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the Xiaoqin Wu, Xiude Fan, Megan R. McMullen, Tatsunori Miyata, Adam Kim, Vai Pathak, Jianguo Wu, Le Z. Day, Josiah E. Hardesty, Nicole Welch, Jaividhya Dasarathy, Daniela S. Allende, Arthur J. McCullough, Jon M. Jacobs, Daniel M. Rotroff, Srinivasan Dasarathy, Laura E. Nagy +16 morewiley +1 more sourceCirculating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness
Hepatology, EarlyView., 2022 Abstract Background and Aims
Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.Vineesh Indira Chandran, Charlotte Wilhelmina Wernberg, Mette Munk Lauridsen, Maria Kløjgaard Skytthe, Sofie Marchsteiner Bendixen, Frederik Tibert Larsen, Camilla Dalby Hansen, Lea Ladegaard Grønkjær, Majken Storm Siersbæk, Tina Di Caterino, Sönke Detlefsen, Holger Jon Møller, Lars Grøntved, Kim Ravnskjaer, Søren Kragh Moestrup, Maja Sofie Thiele, Aleksander Krag, Jonas Heilskov Graversen +17 morewiley +1 more source
