Results 181 to 190 of about 849,024 (375)

Annexin, a Protein for All Seasons: From Calcium Dependent Membrane Metabolism to RNA Recognition

open access: yesBioEssays, EarlyView.
Annexins are an important protein family traditionally well known to bind to phospholipids and to interact with various proteins in a calcium dependent way. More recently, it has been established that a feature common to the family is also to bind to RNA having a role in translation. In bies70019 article, Vedeler et al.
Anni Vedeler   +2 more
wiley   +1 more source

Health related quality of life assessment in patients with hepatitis: a case of Pakistan [PDF]

open access: yes
The intention of this study is to dig out the demographic, medical, economic and psychosocial factors that affect the health related quality of life of the hepatitis B and C patient in district Sargodha.
Abbas, Faisal   +3 more
core   +1 more source

Chronic Viral Hepatitis: Etiology, Pathogenesis of Liver Damage and Mechanisms of Persistence [PDF]

open access: yes, 2004
Chronic hepatotropic viruses commonly evade the antiviral defence systems of the body and cause a long - lasting persistent infection. The prolonged nature of the infection ensures that every infected person has ample opportunity to transmit the virus to
Setiabudi, I. (Irwan)
core  

α‐Azaaryl carbonyl derivatives in stereodivergent catalytic reactions

open access: yesBulletin of the Korean Chemical Society, EarlyView.
This review highlights recent progress in the catalytic synthesis of chiral azaarenes, focusing on α‐azaaryl carbonyl derivatives as versatile precursors. By leveraging chiral Lewis acid catalysis, stereodivergent reactions with diverse electrophiles enable precise construction of multi‐stereogenic azaarenes, offering new opportunities for advanced ...
Ilwoo Song   +3 more
wiley   +1 more source

NAFLD‐related hepatocellular carcinoma: The growing challenge

open access: yesHepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah   +2 more
wiley   +1 more source

Cp*Co(III)‐catalyzed C–H functionalization of bioactive heterocyclic motifs

open access: yesBulletin of the Korean Chemical Society, EarlyView.
Directed carbon–hydrogen bond functionalization of biologically active scaffolds is attractive as it enables the selective modification of sophisticated structures, enhancing the efficiency of drug development by adopting diverse functional groups. This review summarizes recent advances in cobalt‐catalyzed C–H functionalizations of bioactive motifs ...
Yeongmi Park   +3 more
wiley   +1 more source

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

open access: yesHepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou   +13 more
wiley   +1 more source

Hepatitis C virus infection and autoimmune diseases

open access: yesInternational Journal of General Medicine, 2012
Marino Paroli,1 Gino Iannucci,2 Daniele Accapezzato21Department of Biotechnology and Medical-Surgical Sciences, 2Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, ItalyAbstract: Hepatitis C virus (HCV) infection is ...
Paroli M, Iannucci G, Accapezzato D
doaj  

Recent advances of nanomaterials in imaging liver fibrosis

open access: yesBMEMat, EarlyView.
Schematic summary on the latest strategies of liver fibrosis imaging based on various nanomaterials. Abstract Liver fibrosis is a pathological process resulting from prolonged exposure to various injury factors. It is characterized by the abnormal proliferation and activation of hepatic stellate cells and excessive deposition of extracellular matrix ...
Jin Cui   +11 more
wiley   +1 more source

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