Results 231 to 240 of about 849,024 (375)

Development and Recent Advances in SLIPT‐PM: A Chemogenetic Platform for Manipulating Signaling at the Plasma Membrane

ChemBioChem, Accepted Article.
Upon cell stimulation, mammalian cells activate various signaling proteins and lipids by recruiting their upstream regulators to the inner leaflet of the plasma membrane (PM), which in turn determines their cellular response. Therefore, artificially inducing protein translocation to the PM is an effective strategy for dissecting cell signaling networks
Shuya Ohira, Akinobu Nakamura, Kenta Terai, Shinya Tsukiji   +3 more
wiley   +1 more source

Attacking the public health crisis of hepatocellular carcinoma at its roots

Hepatology, EarlyView., 2022
Abstract As the third most common cause of cancer‐related death worldwide with significant mortality rates in the United States, hepatocellular carcinoma has strong association with cirrhosis and chronic hepatitis B virus (HBV) with a growing at‐risk population from the rise in chronic liver disease from alcohol use and nonalcoholic fatty liver disease.
Hannah M. Lee, Steven D. Lidofsky, Tamar H. Taddei, Lisa J. Townshend‐Bulson   +3 more
wiley   +1 more source

Autoantibodies to apolipoprotein A-I in hepatitis C virus infection: a role in disease progression? [PDF]

Front Immunol
Bridge SH, Pagano S, Lodge JK, Shawa IT, Marin-Crespo P, Cramp ME, Sheridan DA, Taylor-Robinson SD, Vuilleumier N, Neely RDG, Bassendine MF.   +10 more
europepmc   +1 more source

Significance of IgM antibody to hepatitis C virus in patients with chronic hepatitis C [PDF]

, 1992
S. Brillanti, C. Masci, Piero Ricci, Mario Miglioli, Luigi Barbara   +4 more
openalex   +1 more source

Reflections and insights into the evolution of restrictive eligibility criteria for cancer clinical trials in China and beyond

Cancer Communications, EarlyView.
Huiyao Huang, Huilei Miao, Jinling Tang, Ning Li   +3 more
wiley   +1 more source

Harnessing Viral Proteases for Cellular and Molecular Engineering

Chemistry–Methods, EarlyView.
Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui, Tien‐Hung Lan, Yubin Zhou   +2 more
wiley   +1 more source

Health disparities in chronic liver disease

Hepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian, Marina Serper, Norah Terrault, Lauren D. Nephew   +3 more
wiley   +1 more source

Disparities in Linkage to Care Among Children With Hepatitis C Virus in the United States. [PDF]

Pediatrics
Curtis MR, Munroe S, Biondi BE, Ciaranello AL, Linas BP, Epstein RL.   +5 more
europepmc   +1 more source

Analysis of a new hepatitis C virus type and its phylogenetic relationship to existing variants

, 1992
Shiu‐Wan Chan, F. McOmish, Edward C. Holmes, B. C. Dow, J F Peutherer, E. A. C. Follett, P.L. Yap, Peter Simmonds   +7 more
openalex   +1 more source

Seroprevalence of hepatitis C virus nucleocapsid antibodies in patients with cryptogenic chronic liver disease [PDF]

, 1992
Jonathan Brown, Spyros P. Dourakis, Peter Karayiannis, Robert Goldin, Joe Chiba, Hiroyoshi Ohba, Tatsuo Miyamura, Howard C. Thomas   +7 more
openalex   +1 more source