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Hepatitis C Virus Infection

New England Journal of Medicine, 2001
Hepatitis C virus (HCV) infects an estimated 170 million persons worldwide and thus represents a viral pandemic, one that is five times as widespread as infection with the human immunodeficiency virus type 1 (HIV-1). The institution of blood-screening measures in developed countries has decreased the risk of transfusion-associated hepatitis to a ...
Georg M. Lauer, Bruce D. Walker
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Hepatitis C virus

2003
Publisher Summary This chapter focuses on hepatitis C virus (HCV), causes viral hepatitis, called non-A, non-B (NANB) hepatitis that spread predominantly via transfusion of blood, blood products, and intravenous drug abuse. The high morbidity and mortality due to HCV infection has provided impetus for ongoing research into biology, epidemiology ...
George J. Dawson, A. Scott Muerhoff
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Hepatitis C virus and the brain

Journal of Viral Hepatitis, 2012
Summary.  Hepatitis C virus (HCV) is an enveloped, positive‐strand RNA virus of the family Flaviviridae that primarily infects hepatocytes, causing acute and chronic liver disease. HCV is also associated with a variety of extrahepatic symptoms including central nervous system (CNS) abnormalities, cognitive dysfunction, fatigue and depression.
Jane A. McKeating, Nicola F. Fletcher
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Hepatitis C Virus

Clinics in Liver Disease, 2005
Chronic infection with hepatitis C virus (HCV) affects approximately 170 million people worldwide and is the most frequent indication for liver transplantation in the United States and Europe. It is estimated that up to four million persons in the United States have been infected with HCV, and analysis of existing data on the current prevalence and ...
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Hepatitis C Virus

1998
Hepatitis C virus - structure, protein products and processing of the polyprotein precursor, M. Houghton et al variability of hepatitis C virus genome, P. Simmonds development of screening and confirmation tests for antibodies to hepatitis C virus, A.-M. Courouce and C. Janot detection of hepatitis C virus RNA - application to diagnostics and research,
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Global epidemiology of hepatitis C virus infection.

Lancet. Infectious Diseases (Print), 2005
C. Shepard, L. Finelli, M. Alter
semanticscholar   +1 more source

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

Nature, 2005
E. Meylan   +6 more
semanticscholar   +1 more source

Hepatitis C Virus

2010
Infection with hepatitis C virus (HCV) has become a global health problem with a prevalence estimated by the World Health Organization of 2%, representing 123 million people. In developed countries, HCV infection is the most common form of chronic viral hepatitis and up to 20% of those chronically infected will develop cirrhosis and 1–4% of these will ...
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