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Hepatitis Delta Virus

Lancet, The, 2011
Hepatitis delta virus (HDV) is a small, defective RNA virus that can infect only individuals who have hepatitis B virus (HBV); worldwide more than 15 million people are co-infected. There are eight reported genotypes of HDV with unexplained variations in their geographical distribution and pathogenicity.
Heiner Wedemeyer, Phillip M Harrison
exaly   +4 more sources

Hepatitis B virus and hepatitis delta virus

1992
Hepatitis B virus (HBV) may cause acute and chronic infection of the liver. Acute hepatitis B infection may cause serious icteric hepatitis or even fulminant hepatitis, though the infection may be anicteric and asymptomatic in a high proportion of cases.
T J, Harrison, G M, Dusheiko
openaire   +2 more sources

Pathobiology of hepatitis delta virus

Journal of Hepatology, 1993
Early observations in humans and infectivity studies in the chimpanzee suggested a direct cytotoxic effect as the major pathogenetic factor in delta hepatitis. Data acquired in liver transplant patients, as well as additional experimental and clinical evidence, have modified this view and indicate instead that liver damage depends on several factors ...
Negro F, RIZZETTO, Mario
openaire   +3 more sources

The Hepatitis Delta Virus: Replication and Pathogenesis [PDF]

open access: yesJournal of Hepatology, 2016
Hepatitis delta virus (HDV) is a defective virus and a satellite of the hepatitis B virus (HBV). Its RNA genome is unique among animal viruses, but it shares common features with some plant viroids, including a replication mechanism that uses a host RNA polymerase.
Francesco Negro
exaly   +4 more sources

Delta Virus Hepatitis

1989
The Hepatitis Delta Virus (HVD) occupies a unique niche in humai virology. At variance with conventional animal viruses, it cannot replicate autonomously but requires the presence of the Hepatitis B Virus (HBV) to initiate infection. It behaves like a defective interfering agent, in that it ihibits the synthesis of the competent HBV helper once its ...
openaire   +2 more sources

Replication of hepatitis delta virus

Journal of Viral Hepatitis, 1996
SUMMARY. Hepatitis delta virus (HDV) is a unique viroid‐like human pathogen that is always associated with hepatitis B infection. Replication of HDV involves the transcription of genomic RNA, probably by the host RNA polymerase II, by a rolling circle mechanism followed by self‐cleavage and self‐ligation. Editing of antigenomic RNA, possibly involving
openaire   +2 more sources

Hepatitis delta: the virus and the disease

Journal of Hepatology, 1990
In general, the biological and structural properties of the hepatitis delta virus resemble those of the viroids and related satellite RNA viruses of plants. This resemblance has been strengthened by the discovery that, in analogy to the self-cleaving of some plant RNA viruses, hepatitis delta virus RNA possesses autocleaving and autoligating sites ...
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Delta Hepatitis and the Hepatitis Delta Virus

1989
Since its discovery in 1977 by Rizzetto and co-workers from Turin, Italy, the hepatitis delta virus (HDV) has become a focus of worldwide interest—interest almost equal to its worldwide importance.1, 2 The delta antigen, which first appeared to be a poorly explained finding of immunofluorescence staining in liver biopsies from Italian chronic hepatitis
openaire   +1 more source

Human Hepatitis Delta Virus

1991
In the past few years significant progress has been made in understanding the structure and replication of hepatitis delta (HDV). Some of this work has been recently reviewed (Bonino et al. 1990; Hoofnagle 1989; Taylor 1990a, b). The present chapter will emphasize those areas in which our perspective has recently changed and those questions about HDV ...
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The Structure and Replication of Hepatitis Delta Virus

Annual Review of Microbiology, 1992
Hepatitis delta virus exists in nature as a satellite of hepatitis B virus. This review emphasizes studies during the past few years that have clarified much about this satellite relationship. Many unique and intriguing features have been assigned to delta and its replication.
openaire   +2 more sources

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